NASDAQ$BCRX

BioCryst Pharmaceuticals Inc · Q3 2022 earnings

Q3 2022 earnings · · Investor relations

Briefing

BioCryst reported Q3 2022 financial results with ORLADEYO net revenue of $66.0 million and an increase in total revenues to $75.8 million.

BioCryst Pharmaceuticals reported strong Q3 2022 financial results, driven by ORLADEYO's net revenue of $66.0 million. Total revenues increased to $75.8 million, and the company is on track to more than double ORLADEYO sales in 2022 compared to 2021.

  • ORLADEYO Q3 2022 net revenue reached $66.0 million, positioning the company to more than double sales in 2022 compared to 2021.
  • Underlying patient trends remained strong, with a nine percent growth in paid patients during Q3 2022.
  • The company expanded its complement pipeline by advancing BCX10013 into clinical development and adding discovery targets.
  • BCX9930 patient screening is underway, with data expected from approximately 15 newly-enrolled patients in mid-2023.

Headline financials

Total Revenue

$75.8M

Previous: $41M+85.0%
EPS (adj)

-$0.23

Previous: -$0.33+30.3%
Free Cash Flow

-$42.5M

Previous: -$58.8M+27.7%
Net Income

-$42.5M

Previous: -$58.8M+27.7%
Operating Income

-$17.4M

Previous: -$44.6M+60.9%
Gross Profit

$72.3M

Previous: $40.4M+78.9%
Cash & Equivalents

$247M

Previous: $200M+23.7%
Total Assets

$559M

Previous: $266M+110.2%
Stock-Based Comp

$9.95M

Previous: $13M-23.6%

Revenue & EPS history

BioCryst · Revenue · Quarterly

$75.8M

Q3 2022+85%vs Q3 2021
Beat estimate in 12 of 15 quarters(80%)
ActualEstimate

Forward guidance

BioCryst expects full year 2022 net ORLADEYO revenue to be $255 million and operating expenses, not including non-cash stock compensation, to be between $365 million and $370 million.

Tailwinds

  • Full year 2022 net ORLADEYO revenue to be $255 million.
  • The company expects to bring rare disease patients many more oral therapies.
  • The company continued to see strong underlying growth fundamentals from patients and physicians in the third quarter.
  • The company expects to see further growth dynamics in the fourth quarter.
  • The company is on track to more than double ORLADEYO revenue in 2022 compared to 2021.

Headwinds

  • The ongoing COVID-19 pandemic could create challenges in all aspects of BioCryst’s business.
  • BioCryst’s ability to successfully implement its commercialization plans for, and to commercialize ORLADEYO, could take longer or be more expensive than planned.
  • The results of BioCryst’s partnerships with third parties may not meet BioCryst’s current expectations.
  • Ongoing and future preclinical and clinical development of BCX9930, BCX10013 and other product candidates may not have positive results.
  • BioCryst may not be able to enroll the required number of subjects in planned clinical trials of product candidates.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q3 2022

Historical avgQ3 2022

-0.3%

Avg return

Earnings day

+3.1%

Avg return

5 days after

+5.6%

Avg return

30 days after

41%

26 / 64 earnings

Positive

+26.0%

Q2 2022

Best reaction

-38.0%

Q3 2012

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-2.2%-5.0%-7.0%
Q4 2025+4.8%+15.1%+23.6%
Q3 2025-5.4%-3.1%+7.2%
Q1 2025+23.7%+11.6%+23.6%
Q4 2024-10.0%-6.5%-15.3%
Q3 2024-16.3%-7.7%-13.0%
Q2 2024+12.1%+8.7%+17.9%
Q1 2024+18.2%+19.6%+52.6%
Q4 2023+2.8%-1.6%-9.8%
Q3 2023+5.4%+5.9%+7.3%
Q2 2023+9.4%+1.0%+4.7%
Q1 2023+14.9%+15.2%+13.3%
Q4 2022-4.2%-10.8%-20.4%
Q3 2022-10.0%-6.8%-2.9%
Q2 2022+26.0%+29.6%+26.2%
Q1 2022-10.7%-15.5%+2.7%
Q4 2021-6.0%-6.4%-9.9%
Q3 2021-23.3%-19.3%-24.4%
Q2 2021+8.3%-6.5%-3.7%
Q1 2021+22.8%+13.7%+52.5%
Q4 2020-8.7%-0.6%-12.4%
Q3 2020-4.4%-4.4%+42.9%
Q2 2020-5.7%-5.9%-13.1%
Q1 2020-0.8%+40.3%+5.6%
Q4 2019+17.1%-19.9%-44.4%
Q3 2019+1.5%-5.9%+31.5%
Q2 2019-2.1%-0.4%+10.6%
Q1 2019+1.7%-1.0%-54.0%
Q4 2018-3.0%-7.5%+0.2%
Q3 2018+0.8%-2.9%+12.9%
Q2 2018+9.2%+24.8%+31.1%
Q1 2018-4.1%-1.1%+10.4%
Q4 2017-1.6%-0.4%-5.5%
Q3 2017-3.1%-0.6%-5.8%
Q2 2017-12.0%-11.2%-2.7%
Q1 2017-12.4%-13.4%-14.7%
Q4 2016+13.7%+39.9%+54.6%
Q3 2016+19.4%+36.6%+40.9%
Q2 2016+2.7%+22.8%+4.2%
Q1 2016-5.3%
Q4 2015-12.0%
Q3 2015-7.6%
Q2 2015-14.1%
Q1 2015+9.2%
Q4 2014-0.1%
Q3 2014+8.1%
Q2 2014-1.4%
Q1 2014+4.6%
Q4 2013-6.0%
Q3 2013+13.2%
Q2 2013-9.1%
Q1 2013-2.7%
Q4 2012-1.6%
Q3 2012-38.0%
Q2 2012-1.2%
Q1 2012-0.5%
Q4 2011+0.2%
Q3 2011-2.0%
Q2 2011-18.0%
Q1 2011+3.0%
Q4 2010-2.6%
Q3 2010-3.2%
Q2 2010-5.1%
Q1 2010+2.1%

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