NASDAQ$BCRX
BioCryst Pharmaceuticals Inc · Q4 2024 earnings
Q4 2024 earnings · · Before market open · Investor relations
Briefing
BioCryst reported strong revenue growth and reduced losses in Q4 2024.
BioCryst Pharmaceuticals posted total revenue of $131.5 million in Q4 2024, a 40.8% increase year-over-year. ORLADEYO sales grew 36.6% to $124.2 million. The company's GAAP net loss improved to $26.8 million from $61.7 million in the prior year quarter. Non-GAAP operating profit reached $16.8 million, compared to a loss of $26.2 million in Q4 2023.
- Total revenue rose 40.8% year-over-year to $131.5 million.
- ORLADEYO net revenue grew 36.6% to $124.2 million.
- GAAP net loss narrowed to $26.8 million from $61.7 million.
- Non-GAAP operating profit of $16.8 million versus a $26.2 million loss last year.
Headline financials
Revenue & EPS history
BioCryst · Revenue · Quarterly
$132M
Forward guidance
BioCryst raised its FY 2025 ORLADEYO revenue guidance to $535-$550 million, up from the previous range of $515-$535 million. The company expects positive EPS and cash flow in the second half of 2025.
Tailwinds
- ORLADEYO revenue guidance raised to $535-$550 million.
- Total revenue projected between $560-$575 million for FY 2025.
- Sustained revenue growth expected to outpace expenses.
- Non-GAAP operating expenses forecasted at $425-$435 million.
- Targeting positive EPS and cash flow in 2H 2025.
Headwinds
- Operating expenses expected to rise due to cost of goods sold and distribution costs.
- Higher incentive compensation may impact short-term profitability.
- Net losses remain despite improvement in profitability metrics.
- Continued investment in pipeline programs may limit near-term cash flow improvements.
- Regulatory approvals for expanded ORLADEYO indications could take longer than expected.
Historical earnings impact
How earnings announcements have historically affected this stock's price.
Avg. return before/after earnings
Based on 20 quarterly earnings reports · overlaid with Q4 2024
-0.3%
Avg return
Earnings day
+3.1%
Avg return
5 days after
+5.6%
Avg return
30 days after
41%
26 / 64 earnings
Positive
+26.0%
Q2 2022
Best reaction
-38.0%
Q3 2012
Worst reaction
| Quarter | Report date | Reaction (Day 0) | +5 days | +30 days |
|---|---|---|---|---|
| Q1 2026 | -2.2% | -5.0% | -7.0% | |
| Q4 2025 | +4.8% | +15.1% | +23.6% | |
| Q3 2025 | -5.4% | -3.1% | +7.2% | |
| Q1 2025 | +23.7% | +11.6% | +23.6% | |
| Q4 2024 | -10.0% | -6.5% | -15.3% | |
| Q3 2024 | -16.3% | -7.7% | -13.0% | |
| Q2 2024 | +12.1% | +8.7% | +17.9% | |
| Q1 2024 | +18.2% | +19.6% | +52.6% | |
| Q4 2023 | +2.8% | -1.6% | -9.8% | |
| Q3 2023 | +5.4% | +5.9% | +7.3% | |
| Q2 2023 | +9.4% | +1.0% | +4.7% | |
| Q1 2023 | +14.9% | +15.2% | +13.3% | |
| Q4 2022 | -4.2% | -10.8% | -20.4% | |
| Q3 2022 | -10.0% | -6.8% | -2.9% | |
| Q2 2022 | +26.0% | +29.6% | +26.2% | |
| Q1 2022 | -10.7% | -15.5% | +2.7% | |
| Q4 2021 | -6.0% | -6.4% | -9.9% | |
| Q3 2021 | -23.3% | -19.3% | -24.4% | |
| Q2 2021 | +8.3% | -6.5% | -3.7% | |
| Q1 2021 | +22.8% | +13.7% | +52.5% | |
| Q4 2020 | -8.7% | -0.6% | -12.4% | |
| Q3 2020 | -4.4% | -4.4% | +42.9% | |
| Q2 2020 | -5.7% | -5.9% | -13.1% | |
| Q1 2020 | -0.8% | +40.3% | +5.6% | |
| Q4 2019 | +17.1% | -19.9% | -44.4% | |
| Q3 2019 | +1.5% | -5.9% | +31.5% | |
| Q2 2019 | -2.1% | -0.4% | +10.6% | |
| Q1 2019 | +1.7% | -1.0% | -54.0% | |
| Q4 2018 | -3.0% | -7.5% | +0.2% | |
| Q3 2018 | +0.8% | -2.9% | +12.9% | |
| Q2 2018 | +9.2% | +24.8% | +31.1% | |
| Q1 2018 | -4.1% | -1.1% | +10.4% | |
| Q4 2017 | -1.6% | -0.4% | -5.5% | |
| Q3 2017 | -3.1% | -0.6% | -5.8% | |
| Q2 2017 | -12.0% | -11.2% | -2.7% | |
| Q1 2017 | -12.4% | -13.4% | -14.7% | |
| Q4 2016 | +13.7% | +39.9% | +54.6% | |
| Q3 2016 | +19.4% | +36.6% | +40.9% | |
| Q2 2016 | +2.7% | +22.8% | +4.2% | |
| Q1 2016 | -5.3% | — | — | |
| Q4 2015 | -12.0% | — | — | |
| Q3 2015 | -7.6% | — | — | |
| Q2 2015 | -14.1% | — | — | |
| Q1 2015 | +9.2% | — | — | |
| Q4 2014 | -0.1% | — | — | |
| Q3 2014 | +8.1% | — | — | |
| Q2 2014 | -1.4% | — | — | |
| Q1 2014 | +4.6% | — | — | |
| Q4 2013 | -6.0% | — | — | |
| Q3 2013 | +13.2% | — | — | |
| Q2 2013 | -9.1% | — | — | |
| Q1 2013 | -2.7% | — | — | |
| Q4 2012 | -1.6% | — | — | |
| Q3 2012 | -38.0% | — | — | |
| Q2 2012 | -1.2% | — | — | |
| Q1 2012 | -0.5% | — | — | |
| Q4 2011 | +0.2% | — | — | |
| Q3 2011 | -2.0% | — | — | |
| Q2 2011 | -18.0% | — | — | |
| Q1 2011 | +3.0% | — | — | |
| Q4 2010 | -2.6% | — | — | |
| Q3 2010 | -3.2% | — | — | |
| Q2 2010 | -5.1% | — | — | |
| Q1 2010 | +2.1% | — | — |
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