NASDAQ$ARVN

Arvinas Inc. · Q1 2022 earnings

Q1 2022 earnings · · Investor relations

Briefing

Reported financial results for the first quarter ended March 31, 2022 and provided a corporate update.

Arvinas reported first quarter 2022 financial results, highlighting a productive quarter as the company prepares to initiate three planned pivotal clinical studies in the second half of 2022 for ARV-471 and bavdegalutamide.

  • Presented Phase 1 dose escalation data and interim data from the ongoing Phase 2 ARDENT expansion cohort with bavdegalutamide in metastatic castration-resistant prostate cancer (mCRPC) at the American Society of Clinical Oncology Genitourinary Cancers Symposium (ASCO GU).
  • Preparing to present data from the VERITAC Phase 2 expansion trial (200 mg and 500 mg) in the second half of 2022.
  • Preparing to discuss the potential accelerated approval path with the Food and Drug Administration (FDA) in Q2 2022 for Bavdegalutamide.
  • Initiate Phase 2 expansion trial in mCRPC for ARV-766 in the second half of 2022.

Headline financials

Total Revenue

$24.2M

Previous: $5.54M+336.9%
EPS (adj)

-$1.20

Previous: -$0.84-42.9%
R&D Expenses

$64M

Previous: $34.9M+83.4%
G&A Expenses

$20.2M

Previous: $12.3M+64.2%
Capital Expenditures

-$2.1M

Previous: -$990K-112.1%
Free Cash Flow

-$65.5M

Previous: -$42M-56.1%
Net Income

-$63.4M

Previous: -$41M-54.8%
Operating Income

-$60M

Previous: -$41.6M-44.1%
Gross Profit

$24.2M

Previous: $5.54M+336.9%
Cash & Equivalents

$62.3M

Previous: $346M-82.0%
Total Assets

$1.49B

Previous: $682M+118.3%
Stock-Based Comp

$16.6M

Previous: $10.3M+61.2%

Revenue & EPS history

Arvinas · Revenue · Quarterly

$24.2M

Q1 2022+336.9%vs Q1 2021
Beat estimate in 9 of 15 quarters(60%)
ActualEstimate

Revenue by segment

Arvinas · $30.3M total across 1 segment · Q3 2022

  • Collaboration Revenue
    $30.3M+225.8%

Forward guidance

Arvinas is focused on advancing its clinical programs and has several milestones expected in 2022.

Tailwinds

  • Present data from the VERITAC Phase 2 expansion trial (200 mg and 500 mg) (2H 2022)
  • Present safety data from the Phase 1b combination trial with palbociclib (2H 2022)
  • Initiate two Phase 3 trials in patients with metastatic breast cancer (as monotherapy and in combination) (2H 2022)
  • Initiate a Phase 1b combination trial with cyclin dependent kinase (CDK) inhibitors or other targeted therapies (2H 2022)
  • Initiate a pivotal trial in mCRPC for patients with AR T878/H875 tumor mutations (2H 2022)

Headwinds

  • The company's net loss increased due to increased research and development expenses, general and administrative expenses, and income tax expense.
  • Decrease in cash, cash equivalents, restricted cash and marketable securities was primarily related to cash used in operating activities and unrealized loss on marketable securities.
  • The company's future success depends on the successful development and commercialization of its product candidates.
  • The company may not be able to obtain marketing approval for its product candidates.
  • The company faces risks and uncertainties related to the Pfizer collaboration.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 19 quarterly earnings reports · overlaid with Q1 2022

Historical avgQ1 2022

-2.4%

Avg return

Earnings day

-2.1%

Avg return

5 days after

-0.6%

Avg return

30 days after

30%

9 / 30 earnings

Positive

+11.8%

Q1 2019

Best reaction

-24.8%

Q1 2025

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-4.4%-10.2%
Q4 2025+5.2%+4.7%-7.4%
Q3 2025+0.5%+17.3%+34.1%
Q1 2025-24.8%-27.8%-25.2%
Q4 2024-6.8%-3.5%-54.9%
Q3 2024-3.9%-2.5%-2.8%
Q2 2024-1.0%-7.0%-6.3%
Q1 2024+0.3%-2.5%-14.1%
Q4 2023-5.8%-3.1%-15.4%
Q3 2023-2.5%-11.5%+93.1%
Q2 2023+2.1%+6.8%+12.8%
Q1 2023+4.9%+3.0%-1.2%
Q4 2022-7.0%-10.8%-23.0%
Q3 2022-4.0%+17.9%-12.5%
Q2 2022+3.8%+4.5%-19.3%
Q1 2022-16.4%-22.6%-19.0%
Q4 2021-2.6%-4.4%-5.4%
Q3 2021+4.9%+1.2%-18.8%
Q2 2021-4.3%-8.9%-13.4%
Q1 2021-4.0%-9.1%-1.7%
Q4 2020-1.0%-8.0%-15.6%
Q3 2020-3.6%+4.3%+18.6%
Q2 2020-5.0%-11.1%-23.0%
Q1 2020-0.9%-6.0%-17.7%
Q4 2019-3.2%-1.8%+14.2%
Q3 2019+3.3%+17.6%+79.4%
Q2 2019-4.6%-0.2%-1.5%
Q1 2019+11.8%+11.1%+0.8%
Q4 2018-3.0%-6.9%+42.9%
Q3 2018-0.1%+7.3%-13.6%
Q2 2018
Q1 2018
Q4 2017
Q3 2017
Q2 2017
Q1 2017

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