EURONEXT-PAR$VALN

Valneva SE · Q3 2025 earnings

Q3 2025 earnings · · Before market open · Investor relations

Briefing

Valneva nine-month revenue up 9% to €127M; debt refinanced ahead of Lyme Phase 3 readout

Valneva SE reported unaudited nine-month 2025 results through September 30, 2025, with total revenues of €127.0 million (+8.9% YoY) and product sales of €119.4 million (+6.2%). The company posted a net loss of €65.2 million compared with net profit of €24.7 million in the prior-year period, which included €90.8 million of one-time proceeds from a Priority Review Voucher sale. Adjusted EBITDA was a loss of €37.7 million versus a €48.6 million profit last year. Operating cash burn improved materially to €28.4 million from €76.7 million. IXIARO/JESPECT sales rose 12.5% to €74.3 million, IXCHIQ contributed €7.6 million, and cash stood at €143.5 million after October debt refinancing with Pharmakon Advisors. Management confirmed 2025 product sales guidance of €155–170 million and total revenue of €165–180 million.

  • Nine-month total revenues were €127.0 million (+8.9% YoY); product sales reached €119.4 million (+6.2%).
  • Net loss was €65.2 million versus €24.7 million net profit in 9M 2024, which included a €90.8M PRV sale gain.
  • Operating cash burn fell to €28.4 million from €76.7 million; cash was €143.5 million at September 30.
  • IXIARO/JESPECT sales rose 12.5% to €74.3 million; IXCHIQ sales reached €7.6 million despite U.S. license suspension.
  • Lyme vaccine Phase 3 VALOR trial on track for H1 2026 readout; 2025 product sales guidance confirmed at €155–170 million.

Headline financials

Total Revenue

€127M

No prior period
Cash and cash equivalents

€144M

No prior period
Adjusted EBITDA

-€37.7M

No prior period
Operating cash used

€28.4M

No prior period
Net Income

-€65.2M

No prior period
Operating Income

-€53.9M

No prior period
Cash & Equivalents

€143M

No prior period

Revenue & EPS history

Valneva · Revenue · Quarterly

€127M

Q3 2025
Beat estimate in 4 of 10 quarters(40%)
ActualEstimate

Revenue by segment

Valneva · €120M total across 4 segments · Q3 2025

  • IXIARO/JESPECT (Japanese encephalitis)
    €74.3M
  • DUKORAL
    €21.5M
  • Third-party distribution
    €16.1M
  • IXCHIQ
    €7.6M

Forward guidance

Valneva confirmed 2025 guidance for product sales of €155–170 million and total revenues of €165–180 million, with R&D investments of €80–90 million partially offset by grants and tax credits.

Tailwinds

  • Commercial business expected to remain cash flow positive
  • Operating cash burn reduced substantially versus prior year
  • Lyme Phase 3 VALOR data expected in H1 2026 with Pfizer regulatory submissions targeted for 2026

Headwinds

  • Nine-month net loss of €65.2 million absent prior-year PRV gain
  • IXCHIQ U.S. license suspension and traveler segment restrictions weighed on chikungunya sales

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 14 quarterly earnings reports · overlaid with Q3 2025

Historical avgQ3 2025

+1.5%

Avg return

Earnings day

+0.8%

Avg return

5 days after

+0.5%

Avg return

30 days after

44%

7 / 16 earnings

Positive

+40.7%

Q1 2023

Best reaction

-16.1%

Q2 2021

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-5.2%-3.3%-10.0%
Q3 2025+0.4%+0.5%-7.2%
H1 2025+29.2%+35.6%+8.0%
Q1 2025+4.0%-0.4%-4.9%
Q1 2024-5.0%-1.1%+11.7%
Q4 2023-10.6%-1.5%-4.3%
Q3 2023+5.3%+2.6%-13.5%
Q2 2023-4.8%-8.0%-19.1%
Q1 2023+40.7%+28.9%+33.6%
Q4 2022-4.5%-10.3%-3.1%
Q3 2022+5.4%+9.4%+5.7%
Q2 2022-0.5%-2.3%-19.5%
Q1 2022+2.1%-3.0%-7.9%
Q4 2021-8.7%-7.6%-13.6%
Q2 2021-16.1%-11.2%+63.3%
Q1 2021-7.1%-15.7%-10.8%

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