EURONEXT-PAR$VALN

Valneva SE · Q1 2025 earnings

Q1 2025 earnings · · Investor relations

Briefing

Valneva Q1 2025: €49.2M revenue (+50%) but net loss €9.2M without PRV gain

Valneva reported first quarter 2025 total revenues of €49.2 million, up 50.3% year over year, driven by product sales of €48.6 million (+51.2%). IXIARO/JESPECT sales rose 65.5% to €27.5 million as prior-year supply constraints eased, DUKORAL grew 9.4% to €12.3 million, and IXCHIQ chikungunya vaccine sales reached €3.0 million. The company posted a net loss of €9.2 million versus a €58.9 million net profit in Q1 2024, which included €90.8 million from the Priority Review Voucher sale. Adjusted EBITDA was a €0.6 million loss compared with €73.0 million profit a year ago. Operating cash burn improved 71% to €8.1 million, and cash stood at €153.0 million at March 31. Valneva confirmed 2025 guidance for product sales of €170–180 million and total revenues of €180–190 million.

  • Total revenues €49.2M (+50%); product sales €48.6M (+51%).
  • IXIARO/JESPECT €27.5M (+66%); DUKORAL €12.3M (+9%); IXCHIQ €3.0M.
  • Net loss €9.2M vs €58.9M profit prior year (prior year included €90.8M PRV gain).
  • Operating cash burn €8.1M, down 71% YoY; cash €153.0M at quarter end.
  • 2025 product sales guidance €170–180M confirmed; Lyme Phase 3 data expected year-end.

Headline financials

Total Revenue

€49.2M

Previous: €35.6M+38.3%
Adjusted EBITDA

-€600K

No prior period
Operating cash used

€8.1M

No prior period
Gross margin ex-IXCHIQ

62.7%

No prior period
Net Income

-€9.2M

No prior period
Operating Income

-€6M

No prior period
Cash & Equivalents

€153M

No prior period

Revenue & EPS history

Valneva · Revenue · Quarterly

€49.2M

Q1 2025+38.3%vs Q1 2024
Beat estimate in 4 of 10 quarters(40%)
ActualEstimate

Revenue by segment

Valneva · €48.6M total across 4 segments · Q1 2025

  • IXIARO/JESPECT
    €27.5M
  • DUKORAL
    €12.3M
  • Third-party distribution
    €5.8M
  • IXCHIQ
    €3M

Forward guidance

Valneva confirmed FY2025 product sales of €170–180M, total revenues €180–190M, R&D spend €90–100M, and targeting >50% lower operating cash burn versus 2024.

Tailwinds

  • Double-digit commercial sales growth with improving IXIARO supply
  • Multiple IXCHIQ regulatory wins including Brazil endemic-country approval

Headwinds

  • IXCHIQ use restricted in elderly populations in U.S., France and EU pending safety reviews
  • Net loss expected until PRV-related prior-year comparison laps

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 14 quarterly earnings reports · overlaid with Q1 2025

Historical avgQ1 2025

+1.5%

Avg return

Earnings day

+0.8%

Avg return

5 days after

+0.5%

Avg return

30 days after

44%

7 / 16 earnings

Positive

+40.7%

Q1 2023

Best reaction

-16.1%

Q2 2021

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-5.2%-3.3%-10.0%
Q3 2025+0.4%+0.5%-7.2%
H1 2025+29.2%+35.6%+8.0%
Q1 2025+4.0%-0.4%-4.9%
Q1 2024-5.0%-1.1%+11.7%
Q4 2023-10.6%-1.5%-4.3%
Q3 2023+5.3%+2.6%-13.5%
Q2 2023-4.8%-8.0%-19.1%
Q1 2023+40.7%+28.9%+33.6%
Q4 2022-4.5%-10.3%-3.1%
Q3 2022+5.4%+9.4%+5.7%
Q2 2022-0.5%-2.3%-19.5%
Q1 2022+2.1%-3.0%-7.9%
Q4 2021-8.7%-7.6%-13.6%
Q2 2021-16.1%-11.2%+63.3%
Q1 2021-7.1%-15.7%-10.8%

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