NYSE$IQV

IQVIA Holdings Inc. · Q4 2025 earnings

Q4 2025 earnings · · Before market open · Investor relations

Briefing

IQVIA reported Q4 2025 revenue of $4.36B, net income of $514M, and adjusted diluted EPS of $3.42.

Fourth-quarter revenue of $4.36 billion increased 10.3% reported (8.1% constant currency). R&D Solutions revenue grew 9.9% to $2.33 billion and TAS revenue grew 9.8% to $1.82 billion. GAAP net income was $514 million ($2.99 diluted EPS); adjusted diluted EPS was $3.42. R&D contracted backlog reached $32.7 billion with a 1.18x quarterly book-to-bill.

  • Q4 revenue $4.36B (+10.3% YoY); R&DS $2.33B, TAS $1.82B.
  • GAAP EPS $2.99; adjusted EPS $3.42.
  • 2026 revenue guide $17.15B–$17.35B; adjusted EPS $12.55–$12.85.
  • Q4 free cash flow $561M; full-year FCF $2.05B (99% of adjusted net income).

Headline financials

Total Revenue

$4.36B

Previous: $3.96B+10.3%
EPS (adj)

$3.42

Previous: $3.12+9.6%
Book-to-bill ratio

1.18

No prior period
R&D Solutions contracted backlog

$32.7B

No prior period
Operating Cash Flow

$735M

No prior period
Adjusted EBITDA

$1.05B

Previous: $996M+5.0%
Net Income

$514M

Previous: $437M+17.6%
Operating Income

$627M

Previous: $626M+0.2%

Revenue & EPS history

IQVIA · Revenue · Quarterly

$4.36B

Q4 2025+10.3%vs Q4 2024
Beat estimate in 12 of 15 quarters(80%)
ActualEstimate

Revenue by segment

IQVIA · $3.74B total across 3 segments · Q3 2023

  • Research & Development Solutions
    $2.12B+7.2%
  • Technology & Analytics Solutions
    $1.43B+2.2%
  • Contract Sales & Medical Solutions
    $183M+0.0%

Forward guidance

Management discusses IQVIA's outlook, including capital deployment, operating priorities, and key risks, alongside any formal guidance in the earnings materials.

Tailwinds

  • IQVIA cites execution on strategic priorities and demand in core markets.
  • Liquidity and balance sheet capacity support continued investment and returns.

Headwinds

  • Macro, rates, and input costs may pressure margins or volumes.
  • Segment mix and non-recurring items can affect sequential comparability.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q4 2025

Historical avgQ4 2025

+1.4%

Avg return

Earnings day

+1.6%

Avg return

5 days after

+1.9%

Avg return

30 days after

65%

37 / 57 earnings

Positive

+12.5%

Q2 2018

Best reaction

-10.7%

Q4 2025

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+7.7%+10.9%+13.9%
Q4 2025-10.7%-9.9%-13.8%
Q3 2025+0.3%-0.4%+6.6%
Q2 2025-0.4%+1.1%-1.6%
Q1 2025-4.0%-2.2%-3.2%
Q4 2024+2.2%-2.2%-6.7%
Q3 2024-3.2%-1.5%-7.0%
Q2 2024+6.3%+6.7%+10.0%
Q1 2024-4.1%-1.6%-5.9%
Q4 2023+12.2%+10.8%+17.4%
Q3 2023+5.3%+9.7%+20.0%
Q2 2023-2.1%-3.1%-0.5%
Q1 2023-0.9%-2.3%+5.0%
Q4 2022+0.8%-1.4%-14.4%
Q3 2022+1.4%+6.1%+11.3%
Q2 2022+0.5%-0.4%+8.3%
Q1 2022+6.1%+5.0%+6.7%
Q4 2021-3.2%-4.8%-6.9%
Q3 2021+2.1%+1.8%+6.6%
Q2 2021-0.8%+0.2%+4.5%
Q1 2021+6.1%+7.0%+9.1%
Q4 2020+4.9%+4.8%+1.6%
Q3 2020+3.2%+2.1%+3.4%
Q2 2020+2.9%+3.4%+0.4%
Q1 2020+8.5%+3.5%+10.9%
Q4 2019+2.5%+1.6%-26.6%
Q3 2019-3.8%-2.4%-2.7%
Q2 2019+2.1%+1.6%-2.3%
Q1 2019-2.0%-0.1%-2.2%
Q4 2018+7.6%+7.3%+7.4%
Q3 2018-3.5%-5.3%-8.4%
Q2 2018+12.5%+8.2%+11.7%
Q1 2018-0.7%+0.2%+2.6%
Q4 2017+1.5%+1.7%+5.6%
Q3 2017+6.1%+6.5%+2.7%
Q2 2017-1.3%-1.0%+4.4%
Q1 2017-3.7%-2.0%+3.0%
Q4 2016-2.7%-4.1%+0.5%
Q3 2016+0.8%+4.1%+3.3%
Q2 2016+3.3%+4.2%+0.3%
Q1 2016-5.9%
Q4 2015+3.6%
Q3 2015-6.2%
Q2 2015+2.6%
Q1 2015-4.9%
Q4 2014+4.3%
Q3 2014+0.9%
Q2 2014-3.1%
Q1 2014+0.4%
Q4 2011+7.5%
Q4 2013+7.5%
Q3 2012+0.1%
Q3 2013+0.1%
Q2 2012+0.8%
Q2 2013+0.8%
Q1 2012+5.0%
Q4 2012+5.0%
Q1 2013

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