NASDAQ$ZLAB

Zai Lab Limited-ADR · Q4 2021 earnings

Q4 2021 earnings · · Investor relations

Briefing

Zai Lab reported strong growth and execution in all areas of the business, expanded its portfolio of assets, and achieved regulatory milestones.

Zai Lab reported strong financial results for the year ended December 31, 2021. The company expanded its portfolio of potential first-in-class and/or best-in-class assets and made meaningful advances with its global pipeline. Commercial execution is gaining strong momentum for marketed products, including ZEJULA's inclusion in the NRDL for first-line ovarian cancer maintenance treatment.

  • Expanded portfolio with potential first-in-class and/or best-in-class assets.
  • Advanced global pipeline of 11 assets, including proof of concept for ZL-1102.
  • Deepened gastric and lung cancer franchises with four additional drug candidates.
  • Achieved additional regulatory submissions and approvals, including first non-oncology approval with NUZYRA®.

Headline financials

Total Revenue

$44.2M

Previous: $49M-9.8%
EPS (adj)

-$2.24

Previous: -$0.04-6300.0%
Capital Expenditures

$6.38M

Previous: $5.3M+20.4%
Free Cash Flow

-$159M

Previous: -$49.6M-221.1%
Net Income

-$704M

Previous: -$269M-162.0%
Operating Income

-$700M

Previous: -$302M-132.0%
Gross Profit

$22.5M

Previous: $42.1M-46.7%
Cash & Equivalents

$964M

Previous: $442M+118.1%
Total Assets

$1.61B

Previous: $1.3B+24.1%
Stock-Based Comp

$12.6M

Previous: $4.43M+184.9%

Revenue & EPS history

Zai Lab · Revenue · Quarterly

$44.2M

Q4 2021-9.8%vs Q4 2020
Beat estimate in 8 of 11 quarters(73%)
ActualEstimate

Revenue by segment

Zai Lab · $52M total across 3 segments · Q3 2023

  • ZEJULA
    $41.6M+6.1%
  • NUZYRA
    $5.5M+266.7%
  • VYVGART franchise
    $4.9M

Forward guidance

Zai Lab has set strategic priorities for 2022, including expediting medicines to patients, investing in R&D, and leveraging its position in China to accelerate revenue growth and source innovation.

Tailwinds

  • Expedite bringing medicines to patients by accelerating data readouts and regulatory filings.
  • File the NDA for efgartigimod in China in mid-2022.
  • Initiate a registrational study in China for bemarituzumab in first-line advanced gastric and GEJ cancer.
  • Move ZL-1102 into full global development and submit up to two INDs for compounds with global rights in 2022.
  • Accelerate growing revenue base and source innovation internally and externally.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q4 2021

Historical avgQ4 2021

-0.1%

Avg return

Earnings day

+0.3%

Avg return

5 days after

-0.5%

Avg return

30 days after

45%

13 / 29 earnings

Positive

+26.0%

Q1 2024

Best reaction

-11.2%

Q2 2023

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-5.9%-7.0%-20.9%
Q4 2025+1.7%-8.6%-7.2%
Q3 2025-6.4%-11.3%-21.4%
Q1 2025+2.5%+0.9%+34.4%
Q4 2024-2.0%-3.1%+6.3%
Q3 2024-3.7%-13.0%-14.1%
Q2 2024-5.6%-7.8%+11.3%
Q1 2024+26.0%+29.0%+19.9%
Q4 2023-0.9%+0.5%-23.7%
Q3 2023+7.4%+0.9%-1.5%
Q2 2023-11.2%-5.4%+3.5%
Q1 2023+1.4%-9.3%-24.2%
Q4 2022-0.6%+7.3%-10.5%
Q3 2022+1.9%+23.9%+18.7%
Q2 2022-5.0%-6.2%-8.0%
Q1 2022-2.1%+30.0%+5.6%
Q4 2021-4.0%-26.0%-19.6%
Q3 2021+0.7%-2.3%-22.3%
Q2 2021+0.6%+0.9%+0.4%
Q1 2021-5.1%-3.3%+8.3%
Q4 2020+0.3%-7.0%-9.6%
Q4 2019-1.4%-2.7%+17.0%
Q1 2020-8.7%+3.1%+18.3%
Q2 2019+4.3%+4.1%-4.0%
Q1 2019+3.7%+6.7%-9.7%
Q4 2018+10.4%+10.4%+1.6%
Q3 2018+6.7%+13.6%+13.1%
Q4 2017-5.3%-8.8%+22.8%
Q3 2017-2.2%-0.6%+0.3%
Q2 2017
Q1 2017
Q4 2016
Q3 2016
Q2 2016
Q1 2016

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