NASDAQ$XERS
Xeris Biopharma Holdings Inc · Q4 2025 earnings
Q4 2025 earnings · · Before market open · Investor relations
Briefing
XERS reported Q4 2025, revenue of $86M, net income of $11.1M, diluted EPS of $0.06.
For Q4 2025, XERS reported revenue of $86M, net income of $11.1M, diluted EPS was $0.06. Management discusses segment performance, capital allocation, and macro risks in the quarterly filing.
- Revenue $86M.
- Net income $11.1M.
- Diluted EPS $0.06.
Headline financials
Revenue & EPS history
Xeris Biopharma · Revenue · Quarterly
$86M
Revenue by segment
Xeris Biopharma · $41.7M total across 3 segments · Q3 2023
- Gvoke$17.7M+29.8%42.5%
- Keveyis$15.9M+18.7%38.0%
- Recorlev$8.1M+221.3%19.4%
Forward guidance
2026 total revenue $375M–$390M (>30% growth at midpoint).
Tailwinds
- Q4 revenue record $86M.
- Q4 net income $11.1M vs loss prior year.
Headwinds
- XP-8121 Phase 3 start costs.
- Product concentration in endocrine portfolio.
Historical earnings impact
How earnings announcements have historically affected this stock's price.
Avg. return before/after earnings
Based on 20 quarterly earnings reports · overlaid with Q4 2025
-0.8%
Avg return
Earnings day
+2.1%
Avg return
5 days after
+4.5%
Avg return
30 days after
40%
12 / 30 earnings
Positive
+33.5%
Q1 2020
Best reaction
-21.8%
Q3 2025
Worst reaction
| Quarter | Report date | Reaction (Day 0) | +5 days | +30 days |
|---|---|---|---|---|
| Q1 2026 | +4.1% | -1.9% | -3.1% | |
| Q4 2025 | -2.0% | -5.1% | -1.3% | |
| Q3 2025 | -21.8% | -24.6% | -34.0% | |
| Q1 2025 | +15.2% | +9.4% | +2.2% | |
| Q4 2024 | +9.5% | +16.4% | +17.0% | |
| Q3 2024 | -2.4% | -6.2% | +9.2% | |
| Q2 2024 | +8.9% | +19.2% | +17.8% | |
| Q1 2024 | -4.9% | +2.7% | +25.9% | |
| Q4 2023 | -20.8% | -26.9% | -33.8% | |
| Q3 2023 | -14.9% | -21.2% | +2.5% | |
| Q2 2023 | -5.6% | -8.4% | -14.1% | |
| Q1 2023 | +22.1% | +20.8% | +22.9% | |
| Q4 2022 | -18.3% | -20.9% | +23.5% | |
| Q3 2022 | +0.0% | -5.3% | -3.3% | |
| Q2 2022 | +7.1% | +11.2% | +7.1% | |
| Q1 2022 | -15.1% | +23.5% | +5.6% | |
| Q4 2021 | +9.3% | +8.1% | -4.5% | |
| Q3 2021 | +6.1% | +26.5% | +13.3% | |
| Q2 2021 | -18.9% | -18.9% | -4.6% | |
| Q1 2021 | +3.3% | +7.8% | +18.6% | |
| Q4 2020 | -8.1% | +1.9% | -9.7% | |
| Q3 2020 | -0.9% | -3.1% | -26.1% | |
| Q2 2020 | -1.8% | +25.1% | +43.6% | |
| Q1 2020 | +33.5% | +62.8% | +100.0% | |
| Q4 2019 | -10.9% | -21.9% | -2.5% | |
| Q3 2019 | -10.1% | -8.2% | -1.9% | |
| Q2 2019 | -1.4% | +5.9% | +5.9% | |
| Q1 2019 | +13.3% | +13.3% | -22.8% | |
| Q4 2018 | -5.8% | -10.4% | -6.2% | |
| Q3 2018 | +5.8% | -9.3% | -13.0% | |
| Q2 2017 | — | — | — | |
| Q1 2017 | — | — | — | |
| Q4 2017 | — | — | — | |
| Q3 2017 | — | — | — |
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