NASDAQ$XERS

Xeris Biopharma Holdings Inc · Q4 2021 earnings

Q4 2021 earnings · · Investor relations

Briefing

Xeris Biopharma reported a net product revenue increase and completed the acquisition of Strongbridge Biopharma.

Xeris Biopharma reported a significant increase in net product revenues for both the fourth quarter and full year 2021, driven by increased demand and the acquisition of Keveyis. The company's cash position remains strong, and they anticipate achieving cash flow breakeven by year-end 2023.

  • Net product revenues increased by $14.3 million, or 201%, for Q4 2021 compared to Q4 2020.
  • Completed the acquisition of Strongbridge Biopharma, expecting $50 million in synergies by year-end 2022.
  • Gvoke prescriptions topped 29,000 in Q4 2021, growing more than 85% compared to the same period in 2020.
  • FDA approved Recorlev for the treatment of endogenous hypercortisolemia in adult patients with Cushing’s syndrome.

Headline financials

Total Revenue

$21.4M

Previous: $7.09M+202.3%
EPS (adj)

-$0.42

Previous: -$0.41-2.4%
Capital Expenditures

$131K

No prior period
Free Cash Flow

-$29.1M

No prior period
Net Income

-$50.8M

No prior period
Operating Income

-$48.3M

No prior period
Gross Profit

$16.5M

No prior period
Cash & Equivalents

$67.3M

No prior period
Total Assets

$304M

No prior period
Stock-Based Comp

$2.74M

No prior period

Revenue & EPS history

Xeris Biopharma · Revenue · Quarterly

$21.4M

Q4 2021+202.3%vs Q4 2020
Beat estimate in 8 of 16 quarters(50%)
ActualEstimate

Forward guidance

Xeris anticipates net product revenue of $105 million to $120 million for full-year 2022 and year-end 2022 cash, cash equivalents, and short-term investments in the range of $90 million to $110 million, with cash flow breakeven expected by year-end 2023.

Tailwinds

  • Net product revenue of $105 million to $120 million for full-year 2022.
  • Year-end 2022 cash, cash equivalents, and short-term investments in the range of $90 million to $110 million.
  • Cash flow breakeven by year-end 2023.
  • Double-digit net product revenues growth expected in 2022.
  • Well-capitalized with cash, cash equivalents, and short-term investments.

Headwinds

  • Expectations for growth assume full access to health care provider facilities.
  • A continuation or escalation of access restrictions or lockdown orders resulting from the ongoing COVID-19 pandemic would adversely affect financial results.
  • Reliance on third-party suppliers for Gvoke, Ogluo, Keveyis and Recorlev.
  • Failure to realize the expected benefits of the acquisition of Strongbridge Biopharma.
  • Changes in global, political, economic, business, competitive, market and regulatory forces.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q4 2021

Historical avgQ4 2021

-0.8%

Avg return

Earnings day

+2.1%

Avg return

5 days after

+4.5%

Avg return

30 days after

40%

12 / 30 earnings

Positive

+33.5%

Q1 2020

Best reaction

-21.8%

Q3 2025

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+4.1%-1.9%-3.1%
Q4 2025-2.0%-5.1%-1.3%
Q3 2025-21.8%-24.6%-34.0%
Q1 2025+15.2%+9.4%+2.2%
Q4 2024+9.5%+16.4%+17.0%
Q3 2024-2.4%-6.2%+9.2%
Q2 2024+8.9%+19.2%+17.8%
Q1 2024-4.9%+2.7%+25.9%
Q4 2023-20.8%-26.9%-33.8%
Q3 2023-14.9%-21.2%+2.5%
Q2 2023-5.6%-8.4%-14.1%
Q1 2023+22.1%+20.8%+22.9%
Q4 2022-18.3%-20.9%+23.5%
Q3 2022+0.0%-5.3%-3.3%
Q2 2022+7.1%+11.2%+7.1%
Q1 2022-15.1%+23.5%+5.6%
Q4 2021+9.3%+8.1%-4.5%
Q3 2021+6.1%+26.5%+13.3%
Q2 2021-18.9%-18.9%-4.6%
Q1 2021+3.3%+7.8%+18.6%
Q4 2020-8.1%+1.9%-9.7%
Q3 2020-0.9%-3.1%-26.1%
Q2 2020-1.8%+25.1%+43.6%
Q1 2020+33.5%+62.8%+100.0%
Q4 2019-10.9%-21.9%-2.5%
Q3 2019-10.1%-8.2%-1.9%
Q2 2019-1.4%+5.9%+5.9%
Q1 2019+13.3%+13.3%-22.8%
Q4 2018-5.8%-10.4%-6.2%
Q3 2018+5.8%-9.3%-13.0%
Q2 2017
Q1 2017
Q4 2017
Q3 2017

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