NASDAQ$VTYX

Ventyx Biosciences Inc · Q1 2024 earnings

Q1 2024 earnings · · Investor relations

Briefing

Reported financial results for the first quarter ended March 31, 2024.

Ventyx Biosciences reported a net loss of $38.6 million for the first quarter of 2024. As of March 31, 2024, the company's cash, cash equivalents, and marketable securities totaled $302.6 million, expected to fund operations into at least the second half of 2026. Phase 2a trials of CNS-Penetrant NLRP3 Inhibitor VTX3232 are expected to initiate in H2 2024.

  • Phase 2a trials of CNS-Penetrant NLRP3 Inhibitor VTX3232 to initiate in H2 2024 in patients with early Parkinson’s disease and in participants with obesity with certain additional cardiovascular risk factors
  • Cash, cash equivalents and marketable securities of $302.6 million as of March 31, 2024 are expected to fund planned operations into at least the second half of 2026
  • Topline Phase 2 data for TYK2 inhibitor VTX958 in Crohn’s disease expected early in the second half of this year.
  • Initiated partnering efforts for S1P1R modulator VTX002 to support a pivotal Phase 3 trial.

Headline financials

Total Revenue

$0.00

No prior period
EPS (adj)

-$0.62

Previous: -$0.68+8.8%
R&D Expenses

$33.7M

No prior period
G&A Expenses

$8.02M

No prior period
Total Operating Expenses

$41.8M

No prior period
Interest Income

$3.23M

No prior period
Capital Expenditures

-$175K

Previous: $60K-391.7%
Net Income

-$38.6M

Previous: -$38.9M+0.9%
Operating Income

-$41.8M

Previous: -$42.6M+1.8%
Gross Profit

-$408K

No prior period
R&D Expense

$33.7M

No prior period
Stock-Based Comp

$6.54M

Previous: $6.57M-0.4%

Revenue & EPS history

Ventyx Biosciences · Revenue · Quarterly

$0

Q1 2024

Forward guidance

Ventyx is focused on advancing its pipeline, including initiating Phase 2a trials for VTX3232 in Parkinson's disease and obesity, and planning for a pivotal Phase 3 trial for VTX002 in ulcerative colitis.

Tailwinds

  • Initiating Phase 2a trials of VTX3232 in Parkinson’s disease and obesity in H2 2024.
  • Evaluating VTX3232 in preclinical rodent models of diet-induced obesity.
  • Evaluating VTX2735 in cardiovascular diseases.
  • Planning for a pivotal Phase 3 trial for VTX002 in UC, supported by a partner or other source of non-dilutive financing.
  • Expect to meet with EMA for a Scientific Advice meeting regarding VTX002.

Headwinds

  • Potential delays in the commencement, enrollment and completion of clinical trials.
  • Dependence on third parties in connection with product manufacturing, research and preclinical and clinical testing.
  • Disruptions in the supply chain, including raw materials needed for manufacturing and animals used in research, delays in site activations and enrollment of clinical trials.
  • Unexpected adverse side effects or inadequate efficacy of Ventyx’s product candidates that may limit their development, regulatory approval and/or commercialization, or may result in recalls or product liability claims.
  • The use of capital resources by Ventyx sooner than expected.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 8 quarterly earnings reports · overlaid with Q1 2024

Historical avgQ1 2024

+4.2%

Avg return

Earnings day

+7.1%

Avg return

5 days after

+13.8%

Avg return

30 days after

56%

10 / 18 earnings

Positive

+34.4%

Q2 2022

Best reaction

-11.9%

Q3 2023

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025
Q3 2025-5.7%+2.5%-6.0%
Q2 2025+18.4%+20.5%+6.8%
Q1 2025+7.0%+1.8%+113.2%
Q4 2024+9.0%+4.2%-16.1%
Q3 2024-5.6%-10.0%+34.2%
Q2 2024+5.6%-0.5%+10.9%
Q1 2024-7.9%-6.3%-26.4%
Q4 2023+32.6%+45.0%-6.5%
Q3 2023-11.9%
Q2 2023+1.9%
Q1 2023-11.6%
Q4 2022-8.3%
Q3 2022-9.1%
Q2 2022+34.4%
Q1 2022+10.6%
Q2 2021+9.3%
Q4 2021+9.3%
Q3 2021-1.7%
Q1 2021
Q4 2020
Q3 2020
Q2 2020
Q1 2020

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