NASDAQ$VTGN
Vistagen Therapeutics Inc · Q4 2021 earnings
Q4 2021 earnings · · Investor relations
Briefing
VistaGen reported financial results for fiscal year 2021 and provided a corporate update.
VistaGen Therapeutics reported sublicense revenue of $1.1 million for the year ended March 31, 2021, stemming from their collaboration agreement with EverInsight Therapeutics. The company's cash and cash equivalents stood at approximately $103.1 million as of March 31, 2021. Net loss for the fiscal year was approximately $17.9 million.
- Reached consensus with the FDA on key aspects of Phase 3 clinical trials of PH94B for acute treatment of anxiety in adults with SAD.
- Entered into a strategic licensing and collaboration agreement with EverInsight Therapeutics for clinical development and commercialization of PH94B in Greater China, South Korea and Southeast Asia, receiving a $5 million upfront payment.
- Reported positive preclinical data differentiating the mechanism of action of PH94B and PH10 from benzodiazepines.
- Raised $127.5 million gross proceeds from partnering and corporate finance transactions.
Headline financials
Revenue & EPS history
Vistagen · Revenue · Quarterly
$442K
Revenue by segment
Vistagen · $1.27M total across 1 segment · Q4 2026
- Sublicense and other revenue$1.27M—100.0%
Forward guidance
VistaGen anticipates topline data from PALISADE-1 in mid-2022 and expects to launch PALISADE-2 later this year. The company also expects to prepare for and initiate several exploratory Phase 2A clinical trials of PH94B in additional anxiety disorders, advance preparations necessary to initiate a U.S. multi-center Phase 2B clinical trial of PH10 as a potential rapid-onset, stand-alone treatment for major depressive disorder, and initiate a Phase 1B clinical trial of AV-101 with probenecid.
Tailwinds
- Topline data from PALISADE-1 expected in mid-2022.
- Launch of PALISADE-2 expected later this year.
- Initiation of Phase 2A clinical trials of PH94B in additional anxiety disorders.
- Advancement of preparations for a Phase 2B clinical trial of PH10 for major depressive disorder.
- Initiation of a Phase 1B clinical trial of AV-101 with probenecid.
Headwinds
- Delays in launching and/or conducting planned clinical trials, including delays due to the impact of the COVID-19 pandemic.
- Fluctuating costs of materials and other resources required to conduct planned clinical and non-clinical trials.
- Impact of general economic, industry or political conditions in the United States or internationally.
- Adverse healthcare reforms and changes of laws and regulations.
- Manufacturing and marketing risks, including unavailability of or delays in delivery of raw materials for manufacture of CNS drug candidates and difficulty in initiating or conducting clinical trials.
Historical earnings impact
How earnings announcements have historically affected this stock's price.
Avg. return before/after earnings
Based on 19 quarterly earnings reports · overlaid with Q4 2021
+2.5%
Avg return
Earnings day
+0.0%
Avg return
5 days after
+1.1%
Avg return
30 days after
39%
23 / 59 earnings
Positive
+94.1%
Q4 2012
Best reaction
-24.0%
Q3 2023
Worst reaction
| Quarter | Report date | Reaction (Day 0) | +5 days | +30 days |
|---|---|---|---|---|
| Q4 2026 | +19.2% | +17.1% | — | |
| Q3 2026 | -3.5% | -7.0% | +7.0% | |
| Q2 2026 | +0.0% | +18.4% | +11.8% | |
| Q1 2026 | +8.1% | +7.3% | +30.0% | |
| Q4 2025 | +7.0% | +5.7% | -3.9% | |
| Q3 2025 | +4.2% | +0.0% | -5.3% | |
| Q2 2025 | +1.3% | -5.5% | -16.1% | |
| Q1 2025 | -2.7% | -2.7% | -5.3% | |
| Q4 2024 | +0.3% | -4.3% | +6.3% | |
| Q3 2024 | +4.7% | -1.0% | -23.9% | |
| Q2 2024 | -16.6% | +3.2% | +51.0% | |
| Q1 2024 | -8.8% | -10.8% | -4.3% | |
| Q4 2023 | +6.5% | +19.5% | +7.1% | |
| Q3 2023 | -24.0% | -28.0% | -44.0% | |
| Q2 2023 | +45.5% | +45.5% | +9.1% | |
| Q1 2023 | -5.9% | -5.9% | +23.5% | |
| Q4 2022 | -3.9% | -10.8% | -85.3% | |
| Q3 2022 | -7.4% | -1.2% | -26.5% | |
| Q2 2022 | +0.4% | -7.7% | -21.0% | |
| Q1 2022 | +2.2% | +0.0% | +11.4% | |
| Q4 2021 | +10.9% | +19.4% | -5.6% | |
| Q3 2021 | -5.0% | -1.0% | +16.9% | |
| Q2 2021 | +2.9% | +5.9% | +8.8% | |
| Q1 2021 | -7.3% | -14.6% | -25.6% | |
| Q4 2020 | +1.9% | +1.9% | +76.9% | |
| Q3 2020 | -12.2% | -10.8% | -45.9% | |
| Q2 2020 | +0.9% | +0.0% | -58.9% | |
| Q1 2020 | -12.7% | -7.3% | +100.0% | |
| Q4 2019 | -5.3% | -2.7% | -30.7% | |
| Q3 2019 | -2.9% | -16.1% | -26.4% | |
| Q2 2019 | -3.3% | -0.9% | -19.3% | |
| Q1 2019 | -3.1% | +2.3% | +8.6% | |
| Q4 2018 | +1.5% | +3.0% | -2.3% | |
| Q3 2018 | +3.4% | +8.6% | +9.5% | |
| Q2 2018 | -1.3% | -3.7% | +125.0% | |
| Q1 2018 | +0.0% | +5.2% | -6.4% | |
| Q4 2017 | +2.2% | -3.3% | +11.5% | |
| Q3 2017 | -10.2% | -19.3% | -28.8% | |
| Q2 2017 | +2.4% | -1.1% | -6.1% | |
| Q1 2017 | +6.3% | +7.8% | +28.5% | |
| Q4 2016 | -9.9% | -4.2% | -8.8% | |
| Q3 2016 | +0.0% | — | — | |
| Q2 2016 | +0.0% | — | — | |
| Q1 2016 | -9.2% | — | — | |
| Q4 2015 | -6.3% | — | — | |
| Q3 2015 | +0.0% | — | — | |
| Q2 2015 | +0.0% | — | — | |
| Q1 2015 | +0.0% | — | — | |
| Q4 2014 | -1.5% | — | — | |
| Q3 2014 | +0.0% | — | — | |
| Q2 2014 | -8.6% | — | — | |
| Q4 2013 | +0.0% | — | — | |
| Q1 2014 | +0.0% | — | — | |
| Q3 2013 | +0.0% | — | — | |
| Q2 2013 | +0.0% | — | — | |
| Q1 2013 | +94.1% | — | — | |
| Q4 2012 | +94.1% | — | — | |
| Q3 2012 | +1.8% | — | — | |
| Q2 2012 | +0.0% | — | — | |
| Q2 2011 | — | — | — | |
| Q4 2011 | — | — | — | |
| Q3 2010 | — | — | — | |
| Q1 2010 | — | — | — | |
| Q4 2010 | — | — | — |
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