NASDAQ$TRDA

Entrada Therapeutics Inc · Q2 2025 earnings

Q2 2025 earnings · · Before market open · Investor relations

Briefing

Entrada Therapeutics Inc reported a net loss of $43.1 million for Q2 2025 driven by increased R&D spending on its DMD programs.

The company recognized $2.0 million in collaboration revenue from its Vertex partnership in the quarter. Operating expenses rose to $48.8 million, primarily from R&D activities advancing ENTR-601-44 and ENTR-601-45. The net loss per share was $1.04 on a basic basis.

  • Collaboration revenue totaled $2.0 million, down significantly from the prior year due to completion of VX-670 research activities.
  • R&D expenses increased 18% year-over-year to $37.9 million, reflecting clinical advancement of DMD candidates.
  • Net loss of $43.1 million resulted in a basic EPS of $(1.04).
  • Cash, cash equivalents and marketable securities stood at $354.0 million, providing runway into Q2 2027.

Headline financials

Total Revenue

$1.95M

Previous: $94.7M-97.9%
EPS (adj)

-$1.04

Previous: $1.55-167.1%
Research and development expenses

$37.9M

No prior period
General and administrative expenses

$10.9M

No prior period
Interest and other income

$3.92M

No prior period
Total operating expenses

$48.8M

No prior period
Stock-based compensation expense

$5.05M

No prior period
Capital Expenditures

-$1.42M

Previous: -$1.88M+24.7%
Net Income

-$43.1M

Previous: $55M-178.3%
Operating Income

-$46.8M

Previous: $53.4M-187.7%

Revenue & EPS history

Entrada Therapeutics · Revenue · Quarterly

$1.95M

Q2 2025-97.9%vs Q2 2024
Beat estimate in 9 of 12 quarters(75%)
ActualEstimate

Revenue by segment

Entrada Therapeutics · $43.7M total across 1 segment · Q3 2023

  • Collaboration revenue
    $43.7M

Forward guidance

No explicit forward guidance provided in the filing.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 17 quarterly earnings reports

Historical avg

-0.8%

Avg return

Earnings day

-0.8%

Avg return

5 days after

-4.5%

Avg return

30 days after

50%

11 / 22 earnings

Positive

+16.0%

Q4 2021

Best reaction

-57.1%

Q1 2026

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q2 2025
Q1 2026-57.1%-55.7%-60.3%
Q4 2025+6.5%-1.1%-0.4%
Q3 2025-2.2%+1.9%+49.9%
Q1 2025-0.2%-5.3%-6.5%
Q4 2024-0.3%-8.6%-20.5%
Q3 2024+5.0%+11.5%+14.4%
Q2 2024+11.3%+16.3%+4.6%
Q1 2024+4.1%+6.2%+17.0%
Q4 2023+5.4%+7.2%+11.8%
Q3 2023+7.9%+6.3%-14.6%
Q2 2023+9.8%+17.7%+5.0%
Q1 2023-0.3%+5.0%+22.6%
Q4 2022+1.4%+14.5%+31.4%
Q3 2022-12.9%-13.7%-19.6%
Q2 2022+0.2%-1.7%+18.3%
Q1 2022+4.9%+8.5%+67.5%
Q4 2021+16.0%+20.4%-1.0%
Q2 2021-3.6%-9.3%-43.6%
Q3 2021-3.6%-9.3%-43.6%
Q4 2020-3.6%-9.3%-43.6%
Q1 2021-3.6%-9.3%-43.6%
Q3 2020-3.6%-9.3%-43.6%
Q2 2020
Q1 2020

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