NASDAQ$TRDA

Entrada Therapeutics Inc · Q1 2024 earnings

Q1 2024 earnings · · Investor relations

Briefing

Entrada Therapeutics reported financial results for Q1 2024 and provided business updates.

Entrada Therapeutics reported a net income of $23.5 million for the first quarter of 2024, a significant increase compared to the net loss of $6.7 million for the same period in 2023. The company's cash, cash equivalents, and marketable securities totaled $327.4 million as of March 31, 2024, and they anticipate their cash runway will extend through the second quarter of 2026.

  • Initiated dosing of the fourth and final cohort of Phase 1 clinical trial of ENTR-601-44 for DMD, with data readout expected in October 2024.
  • Achieved a $75 million milestone payment from Vertex for the clinical advancement of VX-670 for DM1.
  • Cash runway expected through the second quarter of 2026, with $327.4 million in cash, cash equivalents, and marketable securities as of March 31, 2024.
  • On track to submit regulatory applications in the fourth quarter of 2024 to initiate independent global Phase 2 clinical development studies for ENTR-601-44 and ENTR-601-45.

Headline financials

Total Revenue

$59.1M

Previous: $25.3M+134.0%
EPS

$0.68

Previous: -$0.21+423.8%
Capital Expenditures

-$838K

Previous: -$1.67M+49.8%
Free Cash Flow

$22.7M

Previous: -$8.34M+371.6%
Net Income

$23.5M

Previous: -$6.67M+452.1%
Operating Income

$21.1M

Previous: -$5.78M+465.3%
R&D Expense

$27.7M

No prior period
Stock-Based Comp

$3.73M

Previous: $2.76M+35.5%

Revenue & EPS history

Entrada Therapeutics · Revenue · Quarterly

$59.1M

Q1 2024+134%vs Q1 2023
Beat estimate in 9 of 11 quarters(82%)
ActualEstimate

Revenue by segment

Entrada Therapeutics · $43.7M total across 1 segment · Q3 2023

  • Collaboration revenue
    $43.7M

Forward guidance

Entrada anticipates that its cash, cash equivalents and marketable securities as of March 31, 2024, together with ongoing research support from Vertex and the clinical advancement milestone expected to be received in the second quarter of 2024, will be sufficient to extend its cash runway through the second quarter of 2026, supporting the Company's expansion and continued development of EEV therapeutic candidates targeting DMD and advance EEV-therapeutic candidates in indications beyond neuromuscular disease.

Tailwinds

  • Cash runway extended through the second quarter of 2026.
  • Ongoing research support from Vertex.
  • Clinical advancement milestone expected in Q2 2024.
  • Continued development of EEV therapeutic candidates targeting DMD.
  • Advancement of EEV-therapeutic candidates in indications beyond neuromuscular disease.

Headwinds

  • Uncertainties inherent in the identification and development of product candidates.
  • Uncertainties as to the availability and timing of results from preclinical studies and clinical trials.
  • The timing of and Entrada’s ability to submit and obtain regulatory clearance for IND or equivalent foreign applications and initiate or complete clinical trials.
  • Whether results from preclinical studies will be predictive of the results of later preclinical studies and clinical trials.
  • Whether Entrada’s cash resources will be sufficient to fund the Company’s foreseeable and unforeseeable operating expenses and capital expenditure requirements.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 17 quarterly earnings reports · overlaid with Q1 2024

Historical avgQ1 2024

-0.8%

Avg return

Earnings day

-0.8%

Avg return

5 days after

-4.5%

Avg return

30 days after

50%

11 / 22 earnings

Positive

+16.0%

Q4 2021

Best reaction

-57.1%

Q1 2026

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-57.1%-55.7%-60.3%
Q4 2025+6.5%-1.1%-0.4%
Q3 2025-2.2%+1.9%+49.9%
Q1 2025-0.2%-5.3%-6.5%
Q4 2024-0.3%-8.6%-20.5%
Q3 2024+5.0%+11.5%+14.4%
Q2 2024+11.3%+16.3%+4.6%
Q1 2024+4.1%+6.2%+17.0%
Q4 2023+5.4%+7.2%+11.8%
Q3 2023+7.9%+6.3%-14.6%
Q2 2023+9.8%+17.7%+5.0%
Q1 2023-0.3%+5.0%+22.6%
Q4 2022+1.4%+14.5%+31.4%
Q3 2022-12.9%-13.7%-19.6%
Q2 2022+0.2%-1.7%+18.3%
Q1 2022+4.9%+8.5%+67.5%
Q4 2021+16.0%+20.4%-1.0%
Q4 2020-3.6%-9.3%-43.6%
Q3 2020-3.6%-9.3%-43.6%
Q2 2021-3.6%-9.3%-43.6%
Q3 2021-3.6%-9.3%-43.6%
Q1 2021-3.6%-9.3%-43.6%
Q2 2020
Q1 2020

Discussion

Share your read of this quarter. Sign-in carries your eToro identity.

Join the conversation

Sign in with eToro to post your read of this quarter and vote on others'.

Sign in with eToro