NASDAQ$TNGX

Tango Therapeutics Inc · Q4 2025 earnings

Q4 2025 earnings · · Before market open · Investor relations

Briefing

TNGX reported Q4 2025 a net loss of $38.7M, diluted EPS of $-0.29.

For Q4 2025, TNGX reported net loss was $38.7M, diluted EPS was $-0.29. Management discusses segment performance, liquidity, and outlook in the earnings filing.

  • Net loss $38.7M.
  • Diluted EPS $-0.29.
  • MD&A covers capital allocation, costs, and sector risks.

Headline financials

Total Revenue

$0.00

Previous: $4.12M-100.0%
EPS (adj)

-$0.29

Previous: -$0.35+17.1%
R&D Expenses

$32.1M

No prior period
G&A Expenses

$9.76M

No prior period
Operating Expenses

$41.9M

No prior period
Net Income

-$38.7M

Previous: -$37.7M-2.7%
Operating Income

-$41.9M

Previous: -$40.9M-2.3%

Revenue & EPS history

Tango Therapeutics · Revenue · Quarterly

$0

Q4 2025-100%vs Q4 2024
Beat estimate in 6 of 13 quarters(46%)
ActualEstimate

Forward guidance

The filing discusses operating priorities, liquidity, and sector risks; numeric multi-quarter bridges vary by issuer.

Tailwinds

  • MD&A highlights strategic priorities and cash runway.
  • Pipeline, product, or segment commentary supports the narrative.

Headwinds

  • Ongoing losses or impairment charges for pre-profit names.
  • Macro, rates, or input costs may pressure margins.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 18 quarterly earnings reports · overlaid with Q4 2025

Historical avgQ4 2025

+0.6%

Avg return

Earnings day

+6.7%

Avg return

5 days after

+25.8%

Avg return

30 days after

58%

11 / 19 earnings

Positive

+36.4%

Q4 2025

Best reaction

-45.4%

Q3 2024

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+8.6%-12.1%+31.7%
Q4 2025+36.4%+33.6%+75.1%
Q3 2025+0.2%-1.7%+23.6%
Q1 2025+17.1%+31.6%+315.8%
Q4 2024-6.5%-21.0%-36.9%
Q3 2024-45.4%-34.7%-34.7%
Q2 2024-1.8%-5.7%+20.9%
Q1 2024-0.8%-6.9%-12.1%
Q4 2023-9.7%-14.4%-17.4%
Q3 2023+3.8%-12.1%+6.6%
Q2 2023+1.2%+120.9%+113.5%
Q1 2023+6.4%+4.4%-0.3%
Q4 2022-9.4%-5.3%-21.6%
Q3 2022-5.3%+6.7%-1.3%
Q2 2022+22.4%+32.8%-8.1%
Q1 2022-7.6%+1.2%-3.8%
Q4 2021+0.3%+6.8%+1.3%
Q3 2021+0.4%+5.2%-10.7%
Q2 2021+1.1%-2.2%+49.4%

Discussion

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