NASDAQ$TNGX

Tango Therapeutics Inc · Q1 2026 earnings

Q1 2026 earnings · · Investor relations

Briefing

Tango Therapeutics reported Q1 2026 collaboration revenue of $0 with a net loss of $45.5M and diluted loss per share of $0.32.

For the quarter ended March 31, 2026, Tango recognized no collaboration revenue versus $12.5 million in Q1 2025 as prior GSK-related revenue rolled off. Net loss was $45.5 million compared with $28.0 million, with diluted loss per share of $0.32 versus $0.21. R&D expense rose to $42.8 million on synthetic-lethality program advancement.

  • Collaboration revenue fell to $0 from $12.5M year over year.
  • Net loss widened to $45.5M; diluted EPS was a loss of $0.32.
  • R&D expense of $42.8M reflects active oncology pipeline work.
  • Cash and investments support continued clinical trials per MD&A.
  • Lead programs target MTAP-deleted and other synthetic-lethality tumors.

Headline financials

Total Revenue

$0.00

Previous: $5.39M-100.0%
EPS (adj)

-$0.32

Previous: -$0.36+11.1%
Capital Expenditures

-$2K

Previous: -$51K+96.1%
Net Income

-$45.5M

Previous: -$39.9M-14.1%
Operating Income

-$48.8M

Previous: -$42.5M-14.7%

Revenue & EPS history

Tango Therapeutics · Revenue · Quarterly

$0

Q1 2026-100%vs Q1 2025
Beat estimate in 6 of 13 quarters(46%)
ActualEstimate

Forward guidance

Tango does not issue EPS or revenue guidance in the 10-Q and expects continued losses while advancing TNG462 and other targeted oncology candidates.

Tailwinds

  • Strong cash balance supports multi-program clinical execution.
  • Pipeline progress on synthetic-lethality targets continues.

Headwinds

  • Absence of collaboration revenue increased net loss year over year.
  • R&D spend growth pressures cash runway.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 18 quarterly earnings reports · overlaid with Q1 2026

Historical avgQ1 2026

+0.6%

Avg return

Earnings day

+6.7%

Avg return

5 days after

+25.8%

Avg return

30 days after

58%

11 / 19 earnings

Positive

+36.4%

Q4 2025

Best reaction

-45.4%

Q3 2024

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+8.6%-12.1%+31.7%
Q4 2025+36.4%+33.6%+75.1%
Q3 2025+0.2%-1.7%+23.6%
Q1 2025+17.1%+31.6%+315.8%
Q4 2024-6.5%-21.0%-36.9%
Q3 2024-45.4%-34.7%-34.7%
Q2 2024-1.8%-5.7%+20.9%
Q1 2024-0.8%-6.9%-12.1%
Q4 2023-9.7%-14.4%-17.4%
Q3 2023+3.8%-12.1%+6.6%
Q2 2023+1.2%+120.9%+113.5%
Q1 2023+6.4%+4.4%-0.3%
Q4 2022-9.4%-5.3%-21.6%
Q3 2022-5.3%+6.7%-1.3%
Q2 2022+22.4%+32.8%-8.1%
Q1 2022-7.6%+1.2%-3.8%
Q4 2021+0.3%+6.8%+1.3%
Q3 2021+0.4%+5.2%-10.7%
Q2 2021+1.1%-2.2%+49.4%

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