NASDAQ$TECX

Tectonic Therapeutic Inc · Q4 2022 earnings

Q4 2022 earnings · · Investor relations

Briefing

AVROBIO reported financial results for the fourth quarter and year ended Dec. 31, 2022 and provided a business update.

AVROBIO reported a net loss of $25.0 million for the fourth quarter of 2022. As of Dec. 31, 2022, AVROBIO had $92.6 million in cash and cash equivalents.

  • Following positive regulatory feedback, AVROBIO plans to initiate registrational global Phase 2/3 clinical trial for Gaucher disease type 3 (GD3) in second half 2023, subject to regulatory alignment
  • Patient dosing completed in collaborator-sponsored Phase 1/2 clinical trial for cystinosis; plan to initiate late-stage clinical trial activities in second half 2023, subject to regulatory alignment
  • Plan to initiate collaborator-sponsored Phase 1/2 clinical trial for mucopolysaccharidosis type II (MPS-II), or Hunter syndrome, in 2023
  • AVROBIO expects its cash and cash equivalents as of Dec. 31, 2022, will enable AVROBIO to fund its operating expenses and capital expenditure requirements into the first quarter of 2024.

Headline financials

Total Revenue

$0.00

Previous: $0.00
EPS (adj)

-$0.57

Previous: -$0.65+12.3%
Free Cash Flow

-$23.7M

Previous: -$26.7M+11.5%
Net Income

-$25M

Previous: -$28.2M+11.3%
Operating Income

-$25.3M

Previous: -$28M+9.7%
Cash & Equivalents

$92.6M

Previous: $190M-51.2%
Total Assets

$104M

Previous: $204M-49.0%
Stock-Based Comp

$2.26M

Previous: $4.09M-44.8%

Revenue & EPS history

Tectonic · Revenue · Quarterly

$0

Q4 2022

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 17 quarterly earnings reports · overlaid with Q4 2022

Historical avgQ4 2022

-1.4%

Avg return

Earnings day

-1.0%

Avg return

5 days after

+2.9%

Avg return

30 days after

41%

7 / 17 earnings

Positive

+11.1%

Q4 2021

Best reaction

-20.3%

Q4 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025-2.4%+14.5%+22.6%
Q3 2025+1.5%-0.7%+4.9%
Q1 2025-0.9%+3.5%-13.4%
Q4 2024+1.0%-11.8%+11.0%
Q3 2024-2.0%+6.5%+14.8%
Q1 2024+0.0%-0.8%-7.0%
Q4 2023+0.8%-2.3%-1.6%
Q3 2023-9.9%-13.2%-7.2%
Q2 2023+0.6%-1.9%+4.5%
Q1 2023-4.5%-4.5%+82.1%
Q4 2022-20.3%-14.6%-23.6%
Q3 2022-1.5%+12.1%+19.7%
Q2 2022+5.0%+5.9%-12.9%
Q1 2022-7.3%-1.2%+30.5%
Q4 2021+11.1%+12.5%-20.8%
Q3 2021-1.0%-3.8%-40.7%
Q2 2021+6.5%-17.0%-13.5%

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