NASDAQ$TECX

Tectonic Therapeutic Inc · Q1 2022 earnings

Q1 2022 earnings · · Investor relations

Briefing

AVROBIO reported financial results for the first quarter of 2022 and provided a business update.

AVROBIO reported a net loss of $29.8 million for the first quarter of 2022. The company's cash and cash equivalents are expected to fund operating expenses and capital expenditure requirements into the first quarter of 2024.

  • Phase 1/2 collaborator-sponsored clinical trial in cystinosis is now fully enrolled.
  • New interim cystinosis clinical data to be presented at the 25th annual meeting of the American Society of Gene and Cell Therapy (ASGCT).
  • Multiple regulatory interactions planned in 2022 to inform clinical development strategies for cystinosis, Gaucher disease type 3, Hunter syndrome and Pompe disease programs
  • Strong balance sheet with cash runway into Q1 2024.

Headline financials

Total Revenue

$0.00

No prior period
EPS (adj)

-$0.68

No prior period
Net Loss Per Share

-$0.68

No prior period
Capital Expenditures

$32K

No prior period
Free Cash Flow

-$28M

No prior period
Net Income

-$29.8M

No prior period
Operating Income

-$29.4M

No prior period
Cash & Equivalents

$162M

No prior period
Total Assets

$175M

No prior period
Stock-Based Comp

$3.38M

No prior period

Revenue & EPS history

Tectonic · Revenue · Quarterly

$0

Q1 2022

Forward guidance

AVROBIO plans to engage with regulatory agencies to discuss clinical development and regulatory strategy, with the intent of initiating company-sponsored clinical trials in 2023, subject to regulatory alignment.

Tailwinds

  • AVR-RD-04 in cystinosis: Plan to engage in 2022 with regulatory agencies to discuss clinical development and regulatory strategy with the intent of initiating a company-sponsored clinical trial in 2023, subject to regulatory alignment
  • AVR-RD-02 in Gaucher disease type 1: Plan to provide an interim clinical data update in 2022
  • AVR-RD-06 in Gaucher disease type 3: Plan to engage with regulatory agencies on a Phase 2/3 clinical development strategy with aim to initiate a trial in 2023, subject to regulatory alignment
  • AVR-RD-05 in Hunter syndrome: Collaborators at the University of Manchester plan to initiate a Phase 1/2 clinical trial in 2023, subject to regulatory alignment
  • AVR-RD-03 in Pompe disease: Plan to engage with regulatory agencies on clinical development strategy and plan to initiate a clinical trial in 2023, subject to regulatory alignment

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 17 quarterly earnings reports · overlaid with Q1 2022

Historical avgQ1 2022

-1.4%

Avg return

Earnings day

-1.0%

Avg return

5 days after

+2.9%

Avg return

30 days after

41%

7 / 17 earnings

Positive

+11.1%

Q4 2021

Best reaction

-20.3%

Q4 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025-2.4%+14.5%+22.6%
Q3 2025+1.5%-0.7%+4.9%
Q1 2025-0.9%+3.5%-13.4%
Q4 2024+1.0%-11.8%+11.0%
Q3 2024-2.0%+6.5%+14.8%
Q1 2024+0.0%-0.8%-7.0%
Q4 2023+0.8%-2.3%-1.6%
Q3 2023-9.9%-13.2%-7.2%
Q2 2023+0.6%-1.9%+4.5%
Q1 2023-4.5%-4.5%+82.1%
Q4 2022-20.3%-14.6%-23.6%
Q3 2022-1.5%+12.1%+19.7%
Q2 2022+5.0%+5.9%-12.9%
Q1 2022-7.3%-1.2%+30.5%
Q4 2021+11.1%+12.5%-20.8%
Q3 2021-1.0%-3.8%-40.7%
Q2 2021+6.5%-17.0%-13.5%

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