NASDAQ$SLP
Simulations Plus Inc · Q4 2025 earnings
Q4 2025 earnings · · After market close · Investor relations
Briefing
Simulations Plus reported fiscal Q4 2025 revenue of $17.5M with adjusted diluted EPS of $0.10.
Fourth-quarter revenue decreased 6% to $17.5 million and the company posted a GAAP net loss of $0.7 million; adjusted net income was $2.0 million ($0.10 adjusted EPS). Full-year revenue grew 13% to $79.2 million with adjusted EPS of $1.03. Management reaffirmed fiscal 2026 revenue guidance of $79–$82 million and adjusted EPS of $1.03–$1.10.
- Q4 revenue $17.5M; adjusted EPS $0.10.
- FY25 revenue $79.2M (+13%); adjusted EPS $1.03.
- FY26 revenue guide $79M–$82M; adjusted EPS $1.03–$1.10.
- FDA approval of REDEMPLO highlighted for Arrowhead peer context — SLP cites cautious pharma spend.
Headline financials
Revenue & EPS history
Simulations Plus · Revenue · Quarterly
$17.5M
Revenue by segment
Simulations Plus · $15.6M total across 2 segments · Q4 2023
- Software$9.3M+57.6%59.6%
- Services$6.3M+8.6%40.4%
Forward guidance
Simulations Plus reaffirmed fiscal 2026 revenue of $79–$82 million and adjusted diluted EPS of $1.03–$1.10, assuming stable pharma and biotech spending.
Tailwinds
- FY25 revenue grew 13% with adjusted EPS $1.03.
- Cloud and AI workflow investments for FY26.
- Investor Day planned Jan. 2026 for product vision.
Headwinds
- Q4 revenue down 6% YoY on cautious customer spend.
- FY25 GAAP loss included $77.2M impairment.
- Low single-digit growth assumed at guidance midpoint.
Historical earnings impact
How earnings announcements have historically affected this stock's price.
Avg. return before/after earnings
Based on 20 quarterly earnings reports · overlaid with Q4 2025
+0.7%
Avg return
Earnings day
+1.1%
Avg return
5 days after
+4.7%
Avg return
30 days after
60%
39 / 65 earnings
Positive
+23.2%
Q2 2024
Best reaction
-24.2%
Q3 2018
Worst reaction
| Quarter | Report date | Reaction (Day 0) | +5 days | +30 days |
|---|---|---|---|---|
| Q2 2026 | +3.9% | +12.7% | +28.4% | |
| Q1 2026 | +8.5% | +3.4% | -28.1% | |
| Q4 2025 | +14.2% | +14.8% | +6.5% | |
| Q3 2025 | -0.5% | +1.3% | +9.8% | |
| Q2 2025 | +7.8% | +7.3% | +39.9% | |
| Q1 2025 | -3.1% | -2.9% | +22.3% | |
| Q4 2024 | -9.6% | -9.8% | -8.6% | |
| Q3 2024 | -13.6% | -15.8% | -13.4% | |
| Q2 2024 | +23.2% | +28.0% | +21.0% | |
| Q1 2024 | -8.2% | -12.2% | -15.3% | |
| Q4 2023 | -16.2% | -14.9% | -0.4% | |
| Q3 2023 | -3.5% | +4.3% | +16.3% | |
| Q2 2023 | -0.3% | +2.2% | -3.7% | |
| Q1 2023 | -6.1% | -4.4% | +14.7% | |
| Q4 2022 | -12.7% | -10.6% | -11.1% | |
| Q3 2022 | +8.5% | +7.4% | +31.1% | |
| Q2 2022 | +6.9% | +2.6% | -10.4% | |
| Q1 2022 | +4.7% | +1.4% | -14.8% | |
| Q4 2021 | +16.9% | +28.3% | +29.6% | |
| Q3 2021 | -17.4% | -18.6% | -13.2% | |
| Q2 2021 | -2.5% | +0.7% | -12.5% | |
| Q1 2021 | -13.6% | -13.5% | +0.2% | |
| Q4 2020 | -8.4% | -13.5% | -11.5% | |
| Q3 2020 | +1.0% | +0.8% | +6.5% | |
| Q2 2020 | +4.4% | +10.2% | +16.8% | |
| Q1 2020 | +9.1% | +6.8% | +11.5% | |
| Q4 2019 | +3.7% | +5.5% | +0.1% | |
| Q3 2019 | +10.4% | +12.8% | +34.4% | |
| Q2 2019 | +11.8% | +8.1% | +17.4% | |
| Q1 2019 | -7.1% | -5.3% | -4.5% | |
| Q4 2018 | +0.3% | -0.2% | -6.0% | |
| Q3 2018 | -24.2% | -23.4% | -22.5% | |
| Q2 2018 | +9.8% | +10.1% | +24.5% | |
| Q1 2018 | +1.9% | +5.2% | +1.3% | |
| Q4 2017 | -4.5% | -4.2% | -2.1% | |
| Q3 2017 | +5.8% | +8.5% | +8.5% | |
| Q2 2017 | -2.2% | +0.0% | +9.4% | |
| Q1 2017 | +4.2% | +4.7% | +1.6% | |
| Q4 2016 | +2.9% | +4.6% | +10.9% | |
| Q3 2016 | +0.5% | +3.2% | +5.4% | |
| Q2 2016 | -0.8% | — | — | |
| Q1 2016 | +1.5% | — | — | |
| Q4 2015 | +4.6% | — | — | |
| Q3 2015 | +12.6% | — | — | |
| Q2 2015 | +0.7% | — | — | |
| Q1 2015 | -0.9% | — | — | |
| Q4 2014 | -2.0% | — | — | |
| Q3 2014 | +5.7% | — | — | |
| Q2 2014 | +1.0% | — | — | |
| Q1 2014 | +6.3% | — | — | |
| Q4 2013 | -6.1% | — | — | |
| Q3 2013 | +2.8% | — | — | |
| Q2 2013 | +1.0% | — | — | |
| Q1 2013 | -1.6% | — | — | |
| Q4 2012 | +0.9% | — | — | |
| Q3 2012 | -0.7% | — | — | |
| Q3 2011 | -0.7% | — | — | |
| Q2 2012 | +1.1% | — | — | |
| Q1 2012 | +2.0% | — | — | |
| Q1 2011 | +2.0% | — | — | |
| Q4 2011 | +2.0% | — | — | |
| Q2 2011 | +2.0% | — | — | |
| Q4 2010 | +3.1% | — | — | |
| Q3 2010 | +0.8% | — | — | |
| Q2 2009 | -0.9% | — | — |
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