NASDAQ$RYTM

Rhythm Pharmaceuticals Inc · Q3 2025 earnings

Q3 2025 earnings · · Before market open · Investor relations

Briefing

Rhythm Pharmaceuticals reported Q3 2025 revenue of $51.3M, a net loss of $52.9M.

For Q3 2025, Rhythm Pharmaceuticals reported Revenue was $51.3M, net loss was $52.9M. The filing discusses operating performance, liquidity, and outlook in MD&A.

  • Revenue $51.3M for Q3 2025.
  • Net loss $52.9M.
  • MD&A covers liquidity, capital allocation, and sector-specific risks.

Headline financials

Total Revenue

$51.3M

Previous: $33.3M+54.3%
EPS (adj)

-$0.82

Previous: -$0.73-12.3%
Net Income

-$52.9M

Previous: -$43.6M-21.2%
Operating Income

-$52.7M

Previous: -$43.9M-20.0%

Revenue & EPS history

Rhythm Pharmaceuticals · Revenue · Quarterly

$51.3M

Q3 2025+54.3%vs Q3 2024
Beat estimate in 6 of 16 quarters(38%)
ActualEstimate

Forward guidance

Outlook focuses on cash runway, pipeline milestones, and cost discipline toward profitability.

Tailwinds

  • Cash and equivalents support operations into upcoming milestones.
  • Collaboration, licensing, or product pipeline progress noted in MD&A.

Headwinds

  • Ongoing operating losses and R&D spend pressure near-term earnings.
  • Financing, dilution, or partnership timing may affect liquidity.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 19 quarterly earnings reports · overlaid with Q3 2025

Historical avgQ3 2025

+3.1%

Avg return

Earnings day

+2.4%

Avg return

5 days after

+5.4%

Avg return

30 days after

53%

18 / 34 earnings

Positive

+40.8%

Q2 2022

Best reaction

-15.7%

Q2 2021

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q2 2025———
Q1 2026+8.2%+10.3%+2.5%
Q4 2025-0.9%-9.7%-23.5%
Q3 2025-7.7%-11.8%-7.1%
Q1 2025+2.9%-6.0%+8.6%
Q4 2024+4.5%+2.7%+7.4%
Q3 2024+18.2%+27.1%+9.1%
Q2 2024-1.1%+2.8%+9.6%
Q1 2024-11.3%-10.8%-9.6%
Q4 2023-7.5%-5.7%-16.9%
Q3 2023+1.2%+5.1%+40.3%
Q2 2023+36.3%+37.0%+45.8%
Q1 2023-8.4%-17.4%-15.0%
Q4 2022+0.1%-9.8%-26.6%
Q3 2022-2.5%+15.5%+15.7%
Q2 2022+40.8%+62.6%+103.5%
Q1 2022-12.5%-32.1%-46.0%
Q4 2021+21.3%+21.7%+51.2%
Q3 2021+14.4%+14.9%-24.0%
Q2 2021-15.7%-17.5%-22.1%
Q1 2021-0.1%+2.6%-10.5%
Q4 2020+3.2%+0.2%-17.9%
Q3 2020+8.8%+7.9%+51.2%
Q2 2020-2.4%-1.8%+55.2%
Q1 2020+7.1%+8.7%+10.9%
Q4 2019+3.0%-5.4%-22.1%
Q3 2019+0.6%-1.3%+5.3%
Q2 2019-4.7%-2.9%+11.7%
Q1 2019-0.7%-1.0%-2.4%
Q4 2018+5.8%+8.2%+1.6%
Q3 2018-12.3%-15.3%-13.1%
Q2 2018-1.3%-2.8%-5.9%
Q1 2018+17.8%+21.2%+29.9%
Q4 2017+6.9%-16.3%-24.0%
Q3 2017-5.7%+1.3%+10.1%
Q2 2017———
Q1 2017———
Q4 2016———
Q3 2016———
Q2 2016———
Q1 2016———
Q4 2015———
Q3 2015———
Q2 2015———
Q1 2015———
Q4 2014———
Q3 2014———
Q2 2014———
Q1 2014———

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