NASDAQ$RYTM

Rhythm Pharmaceuticals Inc · Q1 2026 earnings

Q1 2026 earnings · · Investor relations

Briefing

Rhythm Pharmaceuticals reported Q1 2026 total revenues of $60.1M (+84% YoY) and a net loss of $55.6M.

For the three months ended March 31, 2026, Rhythm posted total revenues of $60.1 million versus $32.7 million, reflecting Imcivree uptake, while the net loss was $55.6 million as R&D and SG&A scaled with commercial expansion. The rare-disease biotech continues investing in label expansions and geographic launches.

  • Total revenues $60.1M (+84% YoY).
  • Net loss $55.6M as commercial and R&D spend increased.
  • Imcivree rare obesity franchise drives top-line growth.
  • Operating loss before interest reflects investment in launch markets.
  • Cash runway and pipeline indications remain key investor topics.

Headline financials

Total Revenue

$60.1M

Previous: $32.7M+83.8%
EPS (adj)

-$0.83

Previous: -$0.81-2.5%
Net Income

-$55.6M

Previous: -$49.5M-12.4%

Revenue & EPS history

Rhythm Pharmaceuticals · Revenue · Quarterly

$60.1M

Q1 2026+83.8%vs Q1 2025
Beat estimate in 6 of 15 quarters(40%)
ActualEstimate

Forward guidance

Commercial-stage biotech; outlook tied to Imcivree patient adds and pipeline readouts rather than EPS guidance.

Tailwinds

  • Strong double-digit revenue growth on therapy adoption.

Headwinds

  • Continued operating losses until scale improves.
  • Regulatory and reimbursement risks in rare disease.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q1 2026

Historical avgQ1 2026

+3.1%

Avg return

Earnings day

+2.4%

Avg return

5 days after

+5.4%

Avg return

30 days after

53%

18 / 34 earnings

Positive

+40.8%

Q2 2022

Best reaction

-15.7%

Q2 2021

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+8.2%+10.3%+2.5%
Q4 2025-0.9%-9.7%-23.5%
Q3 2025-7.7%-11.8%-7.1%
Q1 2025+2.9%-6.0%+8.6%
Q4 2024+4.5%+2.7%+7.4%
Q3 2024+18.2%+27.1%+9.1%
Q2 2024-1.1%+2.8%+9.6%
Q1 2024-11.3%-10.8%-9.6%
Q4 2023-7.5%-5.7%-16.9%
Q3 2023+1.2%+5.1%+40.3%
Q2 2023+36.3%+37.0%+45.8%
Q1 2023-8.4%-17.4%-15.0%
Q4 2022+0.1%-9.8%-26.6%
Q3 2022-2.5%+15.5%+15.7%
Q2 2022+40.8%+62.6%+103.5%
Q1 2022-12.5%-32.1%-46.0%
Q4 2021+21.3%+21.7%+51.2%
Q3 2021+14.4%+14.9%-24.0%
Q2 2021-15.7%-17.5%-22.1%
Q1 2021-0.1%+2.6%-10.5%
Q4 2020+3.2%+0.2%-17.9%
Q3 2020+8.8%+7.9%+51.2%
Q2 2020-2.4%-1.8%+55.2%
Q1 2020+7.1%+8.7%+10.9%
Q4 2019+3.0%-5.4%-22.1%
Q3 2019+0.6%-1.3%+5.3%
Q2 2019-4.7%-2.9%+11.7%
Q1 2019-0.7%-1.0%-2.4%
Q4 2018+5.8%+8.2%+1.6%
Q3 2018-12.3%-15.3%-13.1%
Q2 2018-1.3%-2.8%-5.9%
Q1 2018+17.8%+21.2%+29.9%
Q4 2017+6.9%-16.3%-24.0%
Q3 2017-5.7%+1.3%+10.1%
Q2 2017
Q1 2017
Q4 2016
Q3 2016
Q2 2016
Q1 2016
Q4 2015
Q3 2015
Q2 2015
Q1 2015
Q4 2014
Q3 2014
Q2 2014
Q1 2014

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