NASDAQ$RVMD

REVOLUTION Medicines Inc · Q4 2024 earnings

Q4 2024 earnings · · After market close · Investor relations

Briefing

Revolution Medicines reported a larger net loss despite strong cash reserves.

Revolution Medicines reported no revenue in Q4 2024, reflecting the termination of its Sanofi collaboration. The company posted a net loss of $194.6 million, driven by increased R&D expenses of $188.1 million. Cash, cash equivalents, and marketable securities reached $2.3 billion following an $823 million public equity offering. The company continues advancing its RAS(ON) inhibitors, with multiple Phase 3 trials underway.

  • Net loss widened to $194.6 million from $161.5 million in Q4 2023.
  • No revenue was reported, down from $742,000 in Q4 2023.
  • R&D expenses increased to $188.1 million due to clinical trial expansions.
  • Cash reserves grew to $2.3 billion following a successful equity offering.

Headline financials

Total Revenue

$0.00

Previous: $742K-100.0%
EPS (adj)

-$1.12

Previous: -$1.14+1.8%
R&D Expenses

$188M

Previous: $148M+26.7%
G&A Expenses

$28.2M

Previous: $32.2M-12.5%
Cash & Marketable Sec.

$2.29B

Previous: $1.85B+23.5%
Total Liabilities

$293M

Previous: $236M+24.5%
Capital Expenditures

-$1.22M

Previous: -$2.32M+47.3%
Net Income

-$195M

Previous: -$162M-20.4%
Operating Income

-$216M

Previous: -$180M-20.2%
Gross Profit

-$3.39M

Previous: -$2.12M-60.1%
R&D Expense

$186M

No prior period

Revenue & EPS history

Revolution Medicines · Revenue · Quarterly

$0

Q4 2024-100%vs Q4 2023
Beat estimate in 3 of 14 quarters(21%)
ActualEstimate

Forward guidance

Revolution Medicines expects a GAAP net loss between $840 million and $900 million for FY 2025, with sufficient cash reserves projected to fund operations into the second half of 2027.

Tailwinds

  • Strong cash position of $2.3 billion following a successful equity raise.
  • Ongoing Phase 3 trials for daraxonrasib in pancreatic and lung cancer.
  • Plans to initiate two additional registrational trials in pancreatic cancer in 2025.
  • Advancing multiple RAS(ON) inhibitor combination therapies.
  • Exploring potential commercial launch strategies, including U.S. field teams.

Headwinds

  • No reported revenue, marking a decline from Q4 2023.
  • Expected net loss of up to $900 million in 2025.
  • High R&D spending continues to drive financial losses.
  • Uncertainty regarding future partnerships outside the U.S.
  • Potential regulatory and competitive risks in the oncology market.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q4 2024

Historical avgQ4 2024

+0.1%

Avg return

Earnings day

+0.2%

Avg return

5 days after

+6.7%

Avg return

30 days after

42%

11 / 26 earnings

Positive

+11.7%

Q3 2020

Best reaction

-11.7%

Q2 2021

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+2.6%-2.1%+1.4%
Q4 2025-0.9%-2.7%-10.4%
Q3 2025+3.5%+8.0%+34.2%
Q2 2025-4.7%-3.8%+10.4%
Q1 2025+11.4%+6.1%+9.1%
Q4 2024-3.5%-6.3%-7.8%
Q3 2024+4.1%+6.8%-15.3%
Q2 2024-3.0%-0.7%-3.3%
Q1 2024-3.7%-4.4%+3.8%
Q4 2023+3.0%+0.2%+6.7%
Q3 2023-3.0%-11.1%+8.2%
Q2 2023-0.1%+1.2%+8.3%
Q1 2023+3.5%+6.3%+10.6%
Q4 2022+10.0%+4.6%-11.5%
Q3 2022-4.1%+8.1%+17.8%
Q2 2022+0.5%+4.2%-11.1%
Q1 2022-6.4%-7.8%+15.4%
Q4 2021-6.4%-12.7%+29.1%
Q3 2021-1.7%-2.5%-24.4%
Q2 2021-11.7%-5.6%+9.7%
Q1 2021+7.1%+8.2%+10.7%
Q4 2020-9.2%-1.1%+1.8%
Q3 2020+11.7%+10.7%+17.4%
Q2 2020+6.9%-3.8%+8.3%
Q1 2020-1.3%+0.8%+4.9%
Q4 2019-2.5%+4.2%+49.6%
Q3 2019
Q2 2019
Q1 2019
Q4 2018

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