NASDAQ$QSI
Quantum-Si Inc · Q4 2025 earnings
Q4 2025 earnings · · After market close · Investor relations
Briefing
Quantum-Si reported Q4 2025 financial results for its next-gen protein sequencing platform.
Quantum-Si reported fourth-quarter and full-year 2025 results for its single-molecule protein sequencing technology, including collaboration revenue, operating expenses, and commercialization milestones.
- Protein sequencing platform commercialization.
- Collaboration and grant revenue streams.
- R&D and instrument placement progress.
- Cash runway and burn rate.
- Life-science tools TAM expansion story.
Headline financials
Revenue & EPS history
Quantum-Si · Revenue · Quarterly
$451K
Forward guidance
2026 milestones focus on instrument placements and partnership revenue.
Tailwinds
- First-mover in accessible protein sequencing.
- Partnerships with pharma and academia.
- Large addressable market in proteomics.
Headwinds
- Early commercial stage with limited revenue.
- Technology adoption risk.
- High cash burn until scale.
Historical earnings impact
How earnings announcements have historically affected this stock's price.
Avg. return before/after earnings
Based on 20 quarterly earnings reports · overlaid with Q4 2025
-4.1%
Avg return
Earnings day
-4.3%
Avg return
5 days after
+1.5%
Avg return
30 days after
39%
9 / 23 earnings
Positive
+14.5%
Q3 2023
Best reaction
-39.5%
Q2 2023
Worst reaction
| Quarter | Report date | Reaction (Day 0) | +5 days | +30 days |
|---|---|---|---|---|
| Q1 2026 | -4.5% | -8.3% | +1.0% | |
| Q4 2025 | -4.3% | -2.3% | -21.1% | |
| Q3 2025 | -8.5% | -12.2% | -20.0% | |
| Q1 2025 | +0.0% | -0.3% | +12.2% | |
| Q4 2024 | +6.2% | -0.8% | -10.8% | |
| Q3 2024 | -20.8% | -26.6% | +81.0% | |
| Q2 2024 | -2.8% | -4.8% | +4.5% | |
| Q1 2024 | -5.6% | +1.7% | -17.8% | |
| Q4 2023 | +6.3% | -7.5% | +13.2% | |
| Q3 2023 | +14.5% | +29.0% | +26.6% | |
| Q2 2023 | -39.5% | -34.8% | -31.9% | |
| Q1 2023 | -13.5% | -15.3% | -1.8% | |
| Q4 2022 | -12.5% | -26.4% | -27.8% | |
| Q3 2022 | +3.2% | +26.8% | -7.6% | |
| Q2 2022 | -6.0% | +9.7% | -14.4% | |
| Q1 2022 | -14.9% | -9.1% | +3.0% | |
| Q4 2019 | +6.2% | -3.8% | +12.5% | |
| Q4 2021 | +6.8% | -9.5% | +13.1% | |
| Q3 2021 | +1.2% | +1.4% | -21.5% | |
| Q2 2021 | +1.9% | +4.4% | +14.2% | |
| Q2 2020 | +1.9% | +4.4% | +14.2% | |
| Q1 2021 | -7.6% | -18.7% | +28.5% | |
| Q4 2020 | -1.1% | +5.0% | -13.8% | |
| Q3 2020 | — | — | — | |
| Q1 2020 | — | — | — |
Discussion
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