NASDAQ$PTCT
PTC Therapeutics, Inc · Q2 2021 earnings
Q2 2021 earnings · · Investor relations
Briefing
PTC Therapeutics' second quarter performance in 2021 showed revenue growth and pipeline advancements.
PTC Therapeutics reported a strong second quarter in 2021, with a 55% increase in total revenue compared to the same period in 2020, reaching $116.7 million. The Duchenne muscular dystrophy (DMD) franchise was a key driver, with $102 million in net product revenue, a 36% increase year-over-year. The company also raised its 2021 DMD franchise revenue guidance to $370-$390 million. Additionally, the company has multiple ongoing clinical trials, three of which are registration-directed clinical studies.
- Total revenue reached $116.7 million, a 55% increase from Q2 2020.
- DMD franchise revenue was $102 million, representing 36% growth year-over-year.
- Translarna revenue grew due to patient base expansion and geographic reach.
- Emflaza revenue increased due to new prescriptions and high compliance.
Headline financials
Revenue & EPS history
PTC Therapeutics · Revenue · Quarterly
$117M
Revenue by segment
PTC Therapeutics · $102M total across 2 segments · Q2 2021
- Translarna$52.6M+36.3%51.7%
- Emflaza$49.1M+35.6%48.3%
Forward guidance
PTC Therapeutics anticipates net product revenues for the DMD franchise for the full year 2021 to be between $370 and $390 million and continues to anticipate GAAP R&D and SG&A expense for the full year 2021 to be between $825 and $855 million.
Tailwinds
- Net product revenues for the DMD franchise for the full year 2021 to be between $370 and $390 million.
- Continue to anticipate GAAP R&D and SG&A expense for the full year 2021 to be between $825 and $855 million.
- Continue to anticipate Non-GAAP R&D and SG&A expense for the full year 2021 to be between $725 and $755 million, excluding estimated non-cash, stock-based compensation expense of $100 million.
- Progress across robust clinical pipeline with 3 ongoing registration-directed trials
- Evrysdi received approval from the Ministry of Health Labor and Welfare in Japan in June 2021.
Headwinds
- The Committee for Medicinal Products for Human Use (CHMP) imposed a clock stop in the aromatic L-amino acid decarboxylase deficiency (AADC-d) review process to allow for completion of its pre-approval inspections.
- This process is still ongoing and therefore the CHMP opinion is now expected in the fourth quarter of 2021.
- There are significant risks in the development, regulatory approval and commercialization of new products.
- significant risks in the development, regulatory approval and commercialization of new products.
- Net loss was $118.4 million for the second quarter of 2021, compared to net loss of $181.4 million for the second quarter of 2020.
Historical earnings impact
How earnings announcements have historically affected this stock's price.
Avg. return before/after earnings
Based on 20 quarterly earnings reports · overlaid with Q2 2021
-2.2%
Avg return
Earnings day
+1.2%
Avg return
5 days after
+5.8%
Avg return
30 days after
46%
26 / 57 earnings
Positive
+24.1%
Q2 2016
Best reaction
-34.0%
Q3 2016
Worst reaction
| Quarter | Report date | Reaction (Day 0) | +5 days | +30 days |
|---|---|---|---|---|
| Q1 2026 | +1.2% | +14.0% | +10.1% | |
| Q4 2025 | +1.1% | -3.1% | -6.6% | |
| Q3 2025 | -1.1% | +3.3% | +6.4% | |
| Q1 2025 | +12.8% | +27.1% | +44.0% | |
| Q4 2024 | +9.3% | +2.7% | +7.3% | |
| Q3 2024 | +2.5% | +3.3% | +11.3% | |
| Q2 2024 | -1.8% | +0.1% | -1.0% | |
| Q1 2024 | +13.3% | +27.5% | +47.6% | |
| Q4 2023 | +13.3% | +11.0% | +3.2% | |
| Q3 2023 | -20.5% | -19.5% | -6.9% | |
| Q2 2023 | -3.7% | -2.9% | -0.3% | |
| Q1 2023 | +5.6% | +5.2% | -18.3% | |
| Q4 2022 | -5.2% | -7.4% | -0.0% | |
| Q3 2022 | -15.7% | -17.3% | -12.9% | |
| Q2 2022 | +11.9% | +8.2% | +8.5% | |
| Q1 2022 | +1.5% | -7.8% | -24.9% | |
| Q4 2021 | -8.8% | -8.7% | -4.1% | |
| Q3 2021 | +7.0% | +12.4% | +7.4% | |
| Q2 2021 | -2.9% | -2.3% | +7.3% | |
| Q1 2021 | +0.3% | -1.3% | -5.6% | |
| Q4 2020 | -0.9% | -0.5% | -14.6% | |
| Q3 2020 | -0.5% | +8.4% | +22.0% | |
| Q2 2020 | -3.0% | -0.9% | -1.0% | |
| Q1 2020 | -10.3% | -7.9% | -5.3% | |
| Q4 2019 | -5.4% | +0.4% | -18.7% | |
| Q3 2019 | +1.9% | +2.4% | +16.8% | |
| Q2 2019 | +8.6% | +10.4% | +1.5% | |
| Q1 2019 | +1.4% | -1.2% | +10.5% | |
| Q4 2018 | +0.9% | -0.7% | +6.8% | |
| Q3 2018 | -12.4% | -14.9% | -13.4% | |
| Q2 2018 | +7.2% | +14.9% | +15.4% | |
| Q1 2018 | -4.7% | -2.6% | +22.8% | |
| Q4 2017 | +10.0% | +8.0% | -2.4% | |
| Q3 2017 | -1.9% | -5.2% | -11.2% | |
| Q2 2017 | -2.1% | -4.7% | +4.3% | |
| Q1 2017 | -3.8% | +6.6% | +26.3% | |
| Q4 2016 | -16.9% | -23.2% | -4.8% | |
| Q3 2016 | -34.0% | -11.2% | +74.5% | |
| Q2 2016 | +24.1% | +24.6% | +26.4% | |
| Q1 2016 | +1.7% | — | — | |
| Q4 2015 | -30.5% | — | — | |
| Q3 2015 | +4.3% | — | — | |
| Q2 2015 | +0.4% | — | — | |
| Q1 2015 | -11.2% | — | — | |
| Q4 2014 | -4.3% | — | — | |
| Q3 2014 | +3.3% | — | — | |
| Q2 2014 | -12.5% | — | — | |
| Q1 2013 | -5.7% | — | — | |
| Q1 2014 | -5.7% | — | — | |
| Q4 2013 | -8.4% | — | — | |
| Q1 2012 | -8.4% | — | — | |
| Q4 2011 | -8.4% | — | — | |
| Q3 2012 | -10.7% | — | — | |
| Q3 2013 | -10.7% | — | — | |
| Q2 2013 | +1.2% | — | — | |
| Q2 2012 | +1.2% | — | — | |
| Q4 2012 | +1.2% | — | — |
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