NASDAQ$ONC

BeiGene Ltd-ADR · Q4 2022 earnings

Q4 2022 earnings · · Investor relations

Briefing

BeiGene's Q4 2022 financial results were reported, featuring revenue growth driven by BRUKINSA and tislelizumab.

BeiGene reported strong fourth quarter and full year 2022 financial results, with product revenue reaching $339.0 million for the quarter and $1.3 billion for the year, representing a 72.3% and 97.9% increase, respectively, compared to the prior-year periods. The growth was primarily driven by increased sales of BRUKINSA and tislelizumab.

  • Product revenue increased by 72.3% in Q4 2022, reaching $339.0 million.
  • BRUKINSA product revenue increased by 101% in Q4 2022, totaling $176.1 million.
  • Tislelizumab product revenue increased by 88% in Q4 2022, amounting to $102.2 million.
  • Net loss for Q4 2022 was $445.3 million, an improvement compared to the prior year period.

Headline financials

Total Revenue

$380M

Previous: $214M+77.6%
EPS (adj)

-$4.29

Previous: -$6.16+30.4%
R&D Expenses

$446M

Previous: $430M+3.6%
SG&A Expenses

$329M

Previous: $307M+7.3%
Capital Expenditures

$121M

Previous: $115M+5.5%
Free Cash Flow

-$440M

Previous: -$623M+29.4%
Net Income

-$445M

Previous: -$586M+24.0%
Operating Income

-$469M

Previous: -$572M+18.0%
Gross Profit

$307M

Previous: $165M+85.3%
Cash & Equivalents

$4.54B

Previous: $6.62B-31.5%
Total Assets

$6.38B

Previous: $8.65B-26.2%
Stock-Based Comp

$78.1M

Previous: $63M+24.0%

Revenue & EPS history

BeiGene · Revenue · Quarterly

$380M

Q4 2022+77.6%vs Q4 2021
Beat estimate in 9 of 14 quarters(64%)
ActualEstimate

Revenue by segment

BeiGene · $176M total across 1 segment · Q4 2022

  • BRUKINSA
    $176M+101.0%

Forward guidance

BeiGene anticipates several milestones in 2023, including regulatory submissions and approvals for BRUKINSA and tislelizumab, as well as data readouts from ongoing clinical trials for various drug candidates. The company also expects to continue expanding its manufacturing capabilities and advancing its collaboration programs.

Tailwinds

  • Submission of sNDA in the U.S. and EU for BRUKINSA in R/R CLL/SLL in the first half of 2023.
  • NMPA review of sNDA for first-line CLL/SLL and WM in China, with a decision expected in the first half of 2023.
  • Continue to support review by regulatory authorities of BeiGene's applications for tislelizumab.
  • Announce final analysis data from pivotal trials in extensive-stage small cell lung cancer and first-line gastric cancer in 2023.
  • Initiate global pivotal trial in first-line CLL in combination with BRUKINSA in the second half of 2023.

Headwinds

  • The COVID-19 pandemic is expected to continue to have a negative impact on operations.
  • Uncertainty remains regarding the future impact of the pandemic both globally and specifically in China due to outbreaks and restrictions and potential impact on clinical, manufacturing and commercial operations.
  • Clinical results for drug candidates may not support further development or marketing approval.
  • Actions of regulatory agencies may affect the initiation, timing and progress of clinical trials and marketing approval.
  • BeiGene's reliance on third parties to conduct drug development, manufacturing, commercialization, and other services.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q4 2022

Historical avgQ4 2022

-0.1%

Avg return

Earnings day

+0.1%

Avg return

5 days after

-2.0%

Avg return

30 days after

40%

16 / 40 earnings

Positive

+15.9%

Q4 2023

Best reaction

-9.6%

Q1 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+5.3%+4.3%-9.4%
Q4 2025-8.5%-15.7%-19.6%
Q3 2025+3.4%+6.9%+0.5%
Q1 2025-3.9%-3.5%+5.8%
Q4 2024+7.5%-0.7%+3.2%
Q3 2024+1.4%-4.5%+1.4%
Q2 2024+6.8%+10.9%+11.7%
Q1 2024-2.0%-2.2%-4.9%
Q4 2023+15.9%+6.4%-0.0%
Q3 2023-0.5%+0.7%-12.6%
Q2 2023-0.3%-9.2%+1.2%
Q1 2023-5.7%-7.3%-14.2%
Q4 2022+4.2%+11.9%+2.9%
Q3 2022-0.2%+7.3%+4.2%
Q2 2022+14.6%+16.4%-1.7%
Q1 2022-9.6%-11.9%-12.9%
Q4 2021-2.5%-0.8%-10.8%
Q3 2021-2.3%-1.1%-15.9%
Q2 2021-6.3%-8.1%-2.0%
Q1 2021+2.2%+5.4%+15.7%
Q4 2020-4.4%-8.5%-3.0%
Q3 2020-3.6%-7.2%-26.8%
Q2 2020-2.9%-7.7%+5.8%
Q1 2020+1.0%+6.0%+9.6%
Q4 2019-2.3%-3.2%-21.8%
Q3 2019+2.9%+3.4%-6.5%
Q2 2019+1.6%+3.9%-7.8%
Q1 2019+14.2%+13.6%+4.3%
Q4 2018-2.1%+8.4%-5.7%
Q3 2018+1.4%-11.2%+10.4%
Q2 2018-3.7%-4.4%-4.7%
Q1 2018-5.2%+4.3%+20.9%
Q4 2017-4.8%+0.3%+11.3%
Q3 2017-5.5%-0.0%+10.4%
Q2 2017-7.3%-9.0%-7.4%
Q1 2017-1.3%+0.7%+3.9%
Q4 2016-2.8%-4.1%-3.1%
Q3 2016-4.7%+7.4%-19.5%
Q2 2016+0.8%+6.0%+11.0%
Q4 2015+5.9%
Q3 2015
Q2 2015
Q1 2015
Q4 2014
Q3 2014
Q2 2014
Q1 2014

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