NASDAQ$MIRM

Mirum Pharmaceuticals Inc · Q4 2024 earnings

Q4 2024 earnings · · After market close · Investor relations

Briefing

Mirum Pharmaceuticals reported its fourth quarter and full-year 2024 financial results, highlighting significant growth in product sales and progress in its clinical pipeline.

Mirum Pharmaceuticals reported strong financial performance in Q4 2024, with total revenue reaching $99.4 million and a net loss of $23.79 million. The company also provided positive full-year 2025 guidance, expecting continued revenue growth and positive cash flow.

  • Total net product sales for 2024 reached $336.4 million, exceeding expectations.
  • The VISTAS study for volixibat in PSC is expected to complete enrollment in the second half of 2025, with topline data anticipated in 2026.
  • CTEXLI (chenodiol) received US approval for cerebrotendinous xanthomatosis.
  • The company ended 2024 with $292.8 million in cash, cash equivalents, and investments, indicating a strong financial position.

Headline financials

Total Revenue

$99.4M

Previous: $69.6M+42.9%
EPS (adj)

-$1.85

Previous: -$0.66-180.3%
R&D Expenses

$44M

Previous: $30.9M+42.3%
SG&A Expenses

$56.8M

Previous: $46.2M+23.1%
Total Operating Expenses

$124M

Previous: $102M+21.0%
Interest Income

$3.2M

Previous: $3.78M-15.1%
Interest Expense

$3.58M

Previous: -$3.56M+200.4%
Income Tax Provision

-$576K

No prior period
Stock-Based Compensation

$13.3M

No prior period
Intangible Amortization

$5.89M

No prior period
Net Income

-$23.8M

Previous: -$33.1M+28.2%
Operating Income

-$24.2M

Previous: -$30.1M+19.5%

Revenue & EPS history

Mirum Pharmaceuticals · Revenue · Quarterly

$99.4M

Q4 2024+42.9%vs Q4 2023
Beat estimate in 12 of 15 quarters(80%)
ActualEstimate

Revenue by segment

Mirum Pharmaceuticals · $29.1M total across 1 segment · Q1 2023

  • Net Product Sales
    $29.1M

Forward guidance

Mirum Pharmaceuticals expects continued revenue growth in 2025, with global net product sales projected to be between $420 million and $435 million, and anticipates achieving positive cash flow.

Tailwinds

  • Expected continued revenue growth in 2025.
  • Anticipated global net product sales of approximately $420 million to $435 million in 2025.
  • Expectation of positive cash flow in 2025.
  • VISTAS study in primary sclerosing cholangitis (PSC) expected to complete enrollment in second half 2025.
  • Expect to initiate Phase 2 study for MRM-3379 in Fragile X Syndrome (FXS) in 2025.

Headwinds

  • No specific negative forward guidance was provided in the report.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q4 2024

Historical avgQ4 2024

+1.7%

Avg return

Earnings day

+0.3%

Avg return

5 days after

+2.9%

Avg return

30 days after

59%

16 / 27 earnings

Positive

+26.4%

Q2 2022

Best reaction

-16.2%

Q3 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+4.0%+0.2%-11.7%
Q4 2025-15.1%-19.2%-18.6%
Q3 2025-1.4%-1.8%-3.5%
Q1 2025+9.9%+9.8%+12.5%
Q4 2024-7.0%-10.5%-9.0%
Q3 2024+5.6%+6.9%+1.6%
Q2 2024+1.8%+14.3%+5.0%
Q1 2024-0.3%-4.4%-3.2%
Q4 2023-3.0%-3.1%-15.2%
Q3 2023+5.6%+5.6%+12.6%
Q2 2023+6.1%+2.1%+6.1%
Q1 2023-8.3%-7.9%-7.9%
Q4 2022-1.1%-4.7%+5.1%
Q3 2022-16.2%-19.7%-24.1%
Q2 2022+26.4%+18.0%+7.4%
Q1 2022+7.1%-4.4%+7.0%
Q4 2021+3.3%+1.5%+29.5%
Q3 2021+0.1%-1.2%-7.9%
Q2 2021+0.5%-4.0%+23.0%
Q1 2021-1.4%-6.3%-10.8%
Q4 2020+6.0%+14.3%+10.2%
Q3 2020+11.6%+16.9%+48.0%
Q2 2020+13.0%+15.3%-4.3%
Q1 2020+0.1%+6.2%+10.8%
Q4 2019+8.1%-10.5%+25.7%
Q3 2019-0.1%+4.0%+22.6%
Q2 2019-9.0%-10.3%-31.5%
Q1 2019
Q4 2018
Q3 2018

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