NASDAQ$LXRX

Lexicon Pharmaceuticals Inc · Q3 2025 earnings

Q3 2025 earnings · · Before market open · Investor relations

Briefing

Lexicon Pharmaceuticals reported Q3 2025, revenue of $14.2M, net loss of $12.8M.

For Q3 2025, Lexicon Pharmaceuticals reported revenue of $14.2M, a net loss of $12.8M. Management discusses segment performance, capital allocation, and outlook in the earnings filing.

  • Revenue $14.2M.
  • Net loss $12.8M.
  • Lexicon Pharmaceuticals highlights liquidity, operations, and 2026 priorities.

Headline financials

Total Revenue

$14.2M

Previous: $1.75M+710.4%
EPS (adj)

$0.04

Previous: -$0.18+122.2%
Capital Expenditures

$0.00

Previous: -$557K+100.0%
Free Cash Flow

-$12.8M

Previous: -$65.4M+80.5%
Net Income

-$12.8M

Previous: -$64.8M+80.3%
Operating Income

-$12.2M

Previous: -$63.7M+80.9%
Gross Profit

$14.2M

Previous: $1.68M+744.1%

Revenue & EPS history

Lexicon Pharmaceuticals · Revenue · Quarterly

$14.2M

Q3 2025+710.4%vs Q3 2024
Beat estimate in 5 of 15 quarters(33%)
ActualEstimate

Revenue by segment

Lexicon Pharmaceuticals · $162K total across 2 segments · Q3 2023

  • Net Product Revenue
    $148K
  • Royalties and Other
    $14K

Forward guidance

The release discusses Lexicon Pharmaceuticals's outlook for upcoming periods, including capital allocation, operating priorities, and market risks, without relying solely on numeric EPS bridges.

Tailwinds

  • Lexicon Pharmaceuticals cites operational execution and demand trends supporting the outlook.
  • Balance sheet and liquidity actions aim to fund growth and returns.

Headwinds

  • GAAP profitability remained under pressure in Q3 2025.
  • Macro, pricing, and input-cost volatility could pressure margins.
  • Segment mix and one-time items may affect quarter-to-quarter comparability.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q3 2025

Historical avgQ3 2025

+0.4%

Avg return

Earnings day

+2.8%

Avg return

5 days after

-0.4%

Avg return

30 days after

56%

36 / 64 earnings

Positive

+30.6%

Q3 2015

Best reaction

-26.0%

Q4 2021

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+4.4%+50.0%+19.4%
Q4 2025-0.6%+1.8%-2.5%
Q3 2025+3.0%+13.0%+1.4%
Q1 2025+3.1%+22.2%+24.1%
Q4 2024+6.6%+2.7%+13.5%
Q3 2024-14.2%-22.8%-35.4%
Q2 2024-24.4%-27.1%-23.1%
Q1 2024+5.5%+7.3%+3.0%
Q4 2023+16.1%+19.8%-6.9%
Q3 2023-17.2%-14.4%+0.0%
Q2 2023-1.1%-3.7%-10.6%
Q1 2023+12.3%+43.0%+11.1%
Q4 2022+21.8%+17.3%+10.5%
Q3 2022+8.7%+13.1%-1.0%
Q2 2022+13.5%+19.4%+16.5%
Q1 2022-7.2%-9.8%-6.7%
Q4 2021-26.0%-25.3%-26.3%
Q3 2021-11.2%-9.8%-25.5%
Q2 2021+2.0%-4.7%+28.8%
Q1 2021-0.4%-3.7%-3.5%
Q4 2020-1.4%-2.6%-23.8%
Q3 2020-9.0%-9.8%+32.8%
Q2 2020+11.5%+12.6%+0.0%
Q1 2020+3.4%-7.3%-1.0%
Q4 2019-10.6%+3.5%-17.2%
Q3 2019-8.6%-8.8%+26.5%
Q2 2019-21.1%-19.9%-20.5%
Q1 2019+4.7%+20.9%-7.2%
Q4 2018+2.2%+6.3%-15.3%
Q3 2018+8.4%+8.8%+3.4%
Q2 2018-3.0%-11.8%-6.2%
Q1 2018+8.4%+17.3%+52.2%
Q4 2017+1.3%+4.5%-1.3%
Q3 2017-6.3%+0.8%+8.4%
Q2 2017-4.4%-3.7%-7.1%
Q1 2017+2.4%+2.2%-9.5%
Q4 2016+9.0%+11.0%-4.8%
Q3 2016-4.2%-3.0%-1.3%
Q2 2016+1.6%+0.6%-11.8%
Q1 2016-15.6%
Q4 2015+24.4%
Q3 2015+30.6%
Q2 2015-8.6%
Q1 2015-5.7%
Q4 2014+14.3%
Q3 2014+2.1%
Q2 2014-6.6%
Q1 2014+1.4%
Q4 2013+3.8%
Q3 2013-2.6%
Q2 2013+7.8%
Q1 2013+2.5%
Q4 2012+1.9%
Q3 2012-9.6%
Q2 2012+3.7%
Q1 2012+1.3%
Q4 2011+5.6%
Q3 2011-9.9%
Q2 2011-7.1%
Q1 2011+1.9%
Q4 2010+6.3%
Q3 2010-3.7%
Q2 2010-0.7%
Q1 2010+8.0%

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