NASDAQ$KNSA

Kiniksa Pharmaceuticals Ltd · Q1 2024 earnings

Q1 2024 earnings · · Investor relations

Briefing

Reported first quarter financial results and portfolio execution.

Kiniksa Pharmaceuticals reported strong first quarter 2024 results, driven by an 85% year-over-year increase in ARCALYST net product revenue, reaching $78.9 million. The company has raised its full-year ARCALYST net product revenue guidance to $370 - $390 million and plans to initiate a Phase 2b trial of abiprubart in Sjögren’s Disease in the second half of 2024. Kiniksa expects to remain cash flow positive on an annual basis.

  • ARCALYST Q1 2024 net product revenue reached $78.9 million, representing 85% year-over-year growth.
  • Increased ARCALYST 2024 expected net product revenue to $370 - $390 million.
  • Planned to initiate Abiprubart Phase 2b trial in Sjögren’s Disease in 2H 2024.
  • Current operating plan expected to remain cash flow positive on an annual basis.

Headline financials

Total Revenue

$79.9M

Previous: $48.3M+65.2%
EPS

-$0.25

Previous: -$0.18-38.9%
Total Operating Expenses

$96.4M

No prior period
Collaboration Expenses

$20.8M

No prior period
Research and Development

$26.3M

No prior period
Selling, General and Administrative

$38.7M

No prior period
Non-cash Share-based Compensation

$7.2M

No prior period
Other Income, Net

$2.27M

No prior period
Provision for Income Taxes

$3.43M

No prior period
Weighted Avg Shares Basic

70.6M

No prior period
Weighted Avg Shares Diluted

70.6M

No prior period
Working Capital

$231M

No prior period
Total Shareholders' Equity

$438M

No prior period
Accumulated Deficit

-$521M

No prior period
Avg Duration of Therapy (Years)

27

No prior period
Capital Expenditures

-$84K

Previous: -$24K-250.0%
Free Cash Flow

-$17.8M

Previous: -$12.3M-44.7%
Net Income

-$17.7M

Previous: -$12.3M-44.3%
Operating Income

-$16.5M

Previous: -$11.2M-47.7%
Gross Profit

$69.3M

Previous: $41.3M+67.7%
R&D Expense

$26.3M

No prior period
Stock-Based Comp

$7.21M

Previous: $6.12M+17.8%

Revenue & EPS history

Kiniksa · Revenue · Quarterly

$79.9M

Q1 2024+65.2%vs Q1 2023
Beat estimate in 12 of 15 quarters(80%)
ActualEstimate

Revenue by segment

Kiniksa · $64.8M total across 1 segment · Q3 2023

  • ARCALYST
    $64.8M+94.0%

Forward guidance

Kiniksa expects ARCALYST net product revenue to be between $370 million and $390 million. The company plans to initiate a Phase 2b clinical trial of abiprubart in Sjögren’s Disease in the second half of 2024 and expects to remain cash flow positive on an annual basis.

Tailwinds

  • ARCALYST 2024 net product revenue will be between $370 million and $390 million.
  • Phase 2b clinical trial of abiprubart in Sjögren’s Disease planned to initiate in 2H 2024.
  • Expectation to remain cash flow positive on an annual basis within current operating plan.
  • Belief that using abiprubart to disrupt the CD40-CD154 co-stimulatory interaction is an attractive approach to address multiple autoimmune disease pathologies.
  • Belief that all product candidates offer the potential for differentiation.

Headwinds

  • Risks arising from the planned redomiciliation of principal holding company from Bermuda to the United Kingdom.
  • Delays or difficulty in enrollment of patients in, and activation or continuation of sites for, clinical trials.
  • Delays or difficulty in completing clinical trials as originally designed.
  • Potential for changes between final data and any preliminary, interim, top-line or other data from clinical trials.
  • Inability to replicate results from earlier clinical trials or studies.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q1 2024

Historical avgQ1 2024

+5.3%

Avg return

Earnings day

+5.2%

Avg return

5 days after

+7.8%

Avg return

30 days after

55%

17 / 31 earnings

Positive

+45.8%

Q3 2021

Best reaction

-16.6%

Q3 2024

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+23.5%+26.7%+16.6%
Q4 2025-4.7%-6.1%-1.3%
Q3 2025-2.9%-8.8%+4.8%
Q1 2025+20.5%+28.8%+26.6%
Q4 2024+0.5%+3.3%+19.0%
Q3 2024-16.6%-18.5%-19.1%
Q2 2024+17.8%+22.1%+22.5%
Q1 2024+4.4%+4.6%+12.1%
Q4 2023+1.2%-3.4%-5.6%
Q3 2023-3.4%+3.3%+3.1%
Q2 2023+35.2%+26.8%+18.1%
Q1 2023+24.2%+24.7%+29.0%
Q4 2022-5.6%-7.8%-19.7%
Q3 2022+8.6%+21.7%+49.3%
Q2 2022+17.3%+29.9%+14.7%
Q1 2022+5.1%-6.8%-18.4%
Q4 2021-6.8%-3.4%-7.2%
Q3 2021+45.8%+41.8%+8.8%
Q2 2021-1.4%-5.4%-10.0%
Q1 2021-9.0%-11.4%-19.4%
Q4 2020-6.3%-11.9%-28.5%
Q3 2020-5.9%-7.2%+9.6%
Q2 2020+0.8%-1.2%-14.7%
Q1 2020-7.0%-9.2%-0.6%
Q4 2019-0.7%+6.1%-29.5%
Q3 2019+15.7%+24.5%+80.8%
Q2 2019-2.4%-12.1%-9.4%
Q1 2019+8.2%+2.6%+6.5%
Q4 2018-6.1%-0.2%+20.2%
Q3 2018+11.9%+5.1%+6.2%
Q2 2018+1.7%+3.5%+78.2%
Q1 2018
Q4 2017
Q3 2017
Q2 2017
Q1 2017

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