NASDAQ$IOVA
Iovance Biotherapeutics Inc. · Q1 2024 earnings
Q1 2024 earnings · · Investor relations
Briefing
Iovance reported first quarter 2024 financial results and corporate updates following FDA approval and strong start for the U.S. commercial launch of Amtagvi™.
Iovance Biotherapeutics reported a net loss of $113.0 million for the first quarter of 2024, with revenue of $0.7 million from Proleukin sales. The company highlighted the strong initial demand for Amtagvi, with over 100 patients enrolled across more than 40 authorized treatment centers.
- Amtagvi U.S. launch is off to a strong start following FDA approval.
- Over 100 patients have enrolled for Amtagvi therapy across more than 40 authorized treatment centers.
- Amtagvi regulatory submissions are on track in the EU, UK, and Canada for 2024.
- Iovance is ramping up the U.S. launch throughout 2024 with additional ATCs.
Headline financials
Revenue & EPS history
Iovance · Revenue · Quarterly
$715K
Forward guidance
Iovance anticipates continued strong launch momentum for Amtagvi in the U.S. throughout 2024 and is progressing with regulatory submissions in Europe and Canada.
Tailwinds
- Strong initial demand for Amtagvi is expected to continue.
- Ramping up the U.S. launch with the authorization of additional ATCs.
- Amtagvi regulatory submissions are on track in the EU, UK, and Canada in 2024.
- Well positioned to remain the global leader in innovating, developing, and delivering TIL cell therapy for patients with cancer.
- Continue to execute across broad clinical pipeline.
Headwinds
- Future competitive or other market factors may adversely affect the commercial potential for Amtagvi or Proleukin.
- The risk that the EMA or other ex-U.S. regulatory authorities may not approve or may delay approval for our marketing authorization application submission for lifileucel in metastatic melanoma.
- The risk whether the number of patients treated and/or ATCs is an appropriate measure of commercial success and/or recognized revenue.
- The risk regarding our ability or inability to manufacture our therapies using third party manufacturers or at our own facility, including our ability to increase manufacturing capacity at such third party manufacturers and our own facility, may adversely affect our commercial launch.
- The risk that the successful development or commercialization of our products, including Amtagvi and Proleukin, may not generate sufficient revenue from product sales, and we may not become profitable in the near term, or at all
Historical earnings impact
How earnings announcements have historically affected this stock's price.
Avg. return before/after earnings
Based on 20 quarterly earnings reports · overlaid with Q1 2024
-1.0%
Avg return
Earnings day
+2.1%
Avg return
5 days after
-1.2%
Avg return
30 days after
37%
20 / 54 earnings
Positive
+36.3%
Q4 2019
Best reaction
-45.1%
Q1 2025
Worst reaction
| Quarter | Report date | Reaction (Day 0) | +5 days | +30 days |
|---|---|---|---|---|
| Q1 2026 | -13.2% | -12.7% | +3.4% | |
| Q4 2025 | +30.1% | +33.6% | +27.7% | |
| Q3 2025 | +27.9% | +46.4% | +21.5% | |
| Q1 2025 | -45.1% | -46.1% | -35.3% | |
| Q4 2024 | -19.4% | -23.0% | -32.3% | |
| Q3 2024 | -12.8% | -20.2% | -25.6% | |
| Q2 2024 | +35.3% | +46.5% | +36.6% | |
| Q1 2024 | -18.1% | -19.9% | -41.9% | |
| Q4 2023 | -8.9% | +72.3% | +67.9% | |
| Q3 2023 | -3.5% | -8.1% | +55.8% | |
| Q2 2023 | +7.8% | +0.1% | -17.7% | |
| Q1 2023 | +7.9% | +5.5% | +13.0% | |
| Q4 2022 | +1.8% | +2.5% | -14.2% | |
| Q3 2022 | +0.0% | -7.0% | -23.1% | |
| Q2 2022 | +1.2% | -0.2% | -8.8% | |
| Q1 2022 | -12.4% | -17.2% | -52.4% | |
| Q4 2021 | +10.2% | +9.4% | +20.5% | |
| Q3 2021 | +0.6% | -0.2% | -33.4% | |
| Q2 2021 | +3.2% | +2.1% | +10.1% | |
| Q1 2021 | -2.4% | -9.3% | -38.7% | |
| Q4 2020 | -5.4% | -5.3% | -27.3% | |
| Q3 2020 | +2.2% | -3.7% | +8.9% | |
| Q2 2020 | -5.3% | -8.8% | -0.7% | |
| Q1 2020 | +1.2% | +12.0% | -4.3% | |
| Q4 2019 | +36.3% | +33.3% | +29.4% | |
| Q3 2019 | -0.7% | +7.5% | +12.5% | |
| Q2 2019 | -3.5% | -8.6% | -14.6% | |
| Q1 2019 | -5.5% | -3.2% | +61.2% | |
| Q4 2018 | -1.7% | +7.8% | -9.0% | |
| Q3 2018 | -3.2% | -5.1% | +5.3% | |
| Q2 2018 | +6.9% | +6.5% | +23.3% | |
| Q1 2018 | +0.7% | +1.0% | -16.2% | |
| Q4 2017 | -8.6% | -11.8% | -21.2% | |
| Q3 2017 | -6.5% | +2.0% | +18.3% | |
| Q2 2017 | -5.1% | -4.3% | -1.7% | |
| Q1 2017 | -9.8% | -11.7% | -24.8% | |
| Q4 2016 | -1.3% | +2.7% | -10.1% | |
| Q3 2016 | +5.1% | +19.7% | +2.6% | |
| Q2 2016 | -2.1% | -1.5% | -11.1% | |
| Q1 2016 | +4.4% | — | — | |
| Q4 2015 | -5.4% | — | — | |
| Q3 2015 | — | — | — | |
| Q4 2014 | +18.7% | — | — | |
| Q1 2013 | -2.8% | — | — | |
| Q2 2013 | -2.8% | — | — | |
| Q4 2012 | +0.0% | — | — | |
| Q3 2012 | -20.0% | — | — | |
| Q2 2012 | -26.0% | — | — | |
| Q1 2012 | +2.6% | — | — | |
| Q4 2011 | -0.9% | — | — | |
| Q3 2011 | -0.8% | — | — | |
| Q2 2011 | -7.1% | — | — | |
| Q1 2011 | +6.1% | — | — | |
| Q4 2010 | +0.0% | — | — | |
| Q3 2010 | -4.5% | — | — | |
| Q2 2010 | — | — | — | |
| Q1 2010 | — | — | — |
Discussion
Share your read of this quarter. Sign-in carries your eToro identity.
Join the conversation
Sign in with eToro to post your read of this quarter and vote on others'.
Sign in with eToro