NASDAQ$GPCR

Structure Therapeutics Inc · Q4 2023 earnings

Q4 2023 earnings · · Investor relations

Briefing

Reported financial results for the fourth quarter and full year ended December 31, 2023, and highlighted recent corporate achievements.

Structure Therapeutics reported its Q4 2023 financial results, highlighting a cash balance of $467.3 million, which is expected to fund operations through 2026. The company's R&D expenses were $20.0 million for the quarter, and G&A expenses were $11.0 million. The net loss for the quarter totaled $24.5 million.

  • Topline GSBR-1290 Phase 2a 12-week obesity data is expected in the latter half of the second quarter 2024.
  • Phase 2b study in obesity is expected to begin as planned in the fourth quarter 2024.
  • Year-end cash balance was $467.3 million, expected to fund operations and key clinical milestones through 2026.
  • R&D expenses for the fourth quarter of 2023 were $20.0 million.

Headline financials

Total Revenue

$1.33M

No prior period
EPS (adj)

-$0.16

Previous: -$1.17+86.3%
Research and Development Expenses

$20M

No prior period
General and Administrative Expenses

$11M

No prior period
Cash, Cash Equivalents and Short-Term Investments

$467M

No prior period
Share-Based Compensation Expense

$1.9M

No prior period
Capital Expenditures

-$1.16M

Previous: $71K-1731.7%
Net Income

-$24.5M

Previous: -$11.9M-106.3%
Operating Income

-$31.2M

Previous: -$13M-140.9%
Gross Profit

$1.05M

No prior period
R&D Expense

$20.2M

No prior period
Stock-Based Comp

$2.1M

Previous: $623K+236.8%

Revenue & EPS history

Structure Therapeutics · Revenue · Quarterly

$1.33M

Q4 2023

Forward guidance

Structure Therapeutics is focused on advancing its clinical programs, particularly GSBR-1290, and expects to achieve key clinical milestones through 2026 with its current cash reserves.

Tailwinds

  • GSBR-1290 Phase 2a 12-week obesity data on track for latter half of the second quarter 2024.
  • Phase 2b study in obesity expected to begin as planned in the fourth quarter 2024.
  • Cash balance of $467.3 million expected to fund operations and key clinical milestones through 2026.
  • Advancing development of oral small molecule programs targeting amylin, GIP, and apelin receptors.
  • Differentiated oral small molecule with scalability and manufacturing advantages.

Headwinds

  • Potential risks and uncertainties related to clinical trial results.
  • Dependence on successful development and commercialization of therapeutic candidates.
  • Impact of global pandemics, inflation, and supply chain issues on the business.
  • Risks related to protecting intellectual property.
  • Uncertainties related to regulatory approvals.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 15 quarterly earnings reports · overlaid with Q4 2023

Historical avgQ4 2023

+1.2%

Avg return

Earnings day

-1.1%

Avg return

5 days after

+9.8%

Avg return

30 days after

40%

6 / 15 earnings

Positive

+14.8%

Q4 2024

Best reaction

-11.6%

Q3 2023

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2026-2.6%-2.5%-29.1%
Q3 2025-2.0%+7.3%+3.3%
Q1 2025-4.6%-11.2%-21.2%
Q4 2024+14.8%+13.1%-0.6%
Q3 2024+1.9%-14.1%-15.5%
Q2 2024-0.8%+0.9%+8.6%
Q1 2024-8.7%-9.0%+35.3%
Q4 2023-2.5%-5.9%+15.1%
Q3 2022+11.5%+7.1%+23.4%
Q3 2023-11.6%-1.6%+7.2%
Q2 2023-1.9%-2.9%-0.1%
Q2 2022-1.9%-2.9%-0.1%
Q1 2023+8.9%+1.9%+40.2%
Q4 2022+8.9%+1.9%+40.2%
Q1 2022+8.9%+1.9%+40.2%
Q4 2021

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