NASDAQ$GPCR

Structure Therapeutics Inc · Q1 2024 earnings

Q1 2024 earnings · · Investor relations

Briefing

Structure Therapeutics reported financial results for the first quarter ended March 31, 2024, and highlighted recent corporate achievements.

Structure Therapeutics reported a net loss of $26.0 million for the first quarter of 2024. The company's cash, cash equivalents, and short-term investments totaled $436.4 million as of March 31, 2024, which is expected to fund operations through at least 2026.

  • Topline GSBR-1290 Phase 2a 12-week obesity data on track for June 2024
  • Phase 2b study in obesity expected to begin as planned in the fourth quarter 2024
  • Plan to initiate dosing in first-in-human Phase 1 clinical trial of oral small molecule LPA1R Antagonist, LTSE-2578, for idiopathic pulmonary fibrosis in June 2024
  • Cash, cash equivalents and short-term investments totaled $436.4 million on March 31, 2024.

Headline financials

Total Revenue

$0.00

No prior period
EPS (adj)

-$0.19

Previous: -$25.00+99.2%
Capital Expenditures

-$162K

No prior period
Free Cash Flow

-$34.2M

No prior period
Net Income

-$26M

Previous: -$18M-44.6%
Operating Income

-$32M

Previous: -$19.6M-62.9%
Gross Profit

-$659K

No prior period
R&D Expense

$20.6M

No prior period
Stock-Based Comp

$2.74M

Previous: $2.53M+8.3%

Revenue & EPS history

Structure Therapeutics · Revenue · Quarterly

$0

Q1 2024

Forward guidance

The company anticipates several milestones, including the release of Phase 2a data for GSBR-1290 in June, the initiation of a Phase 2b obesity study later in the year, and the start of a Phase 1 clinical trial for LTSE-2578 in June 2024.

Tailwinds

  • Topline GSBR-1290 Phase 2a 12-week obesity data on track for June 2024
  • Phase 2b study in obesity expected to begin as planned in the fourth quarter 2024
  • Plan to initiate dosing in first-in-human Phase 1 clinical trial of oral small molecule LPA1R Antagonist, LTSE-2578, for idiopathic pulmonary fibrosis in June 2024
  • Advancement of the Company’s GLP-1R franchise and other research programs
  • Planned timing of the Company’s data results and continued development of GSBR-1290, ANPA-0073, amylin, GIPR and next generation GLP-1R/GIPR combination candidates

Headwinds

  • Risks and uncertainties related to the preliminary nature of the results due to length of the study and sample size
  • The risks that unblinded data is not consistent with blinded data
  • The Company’s ability to advance GSBR-1290, LTSE-2578, ANPA-0073 and its other therapeutic candidates
  • The timing and results of preclinical and clinical trials
  • The impact of any data collection omissions at any of our clinical sites

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 15 quarterly earnings reports · overlaid with Q1 2024

Historical avgQ1 2024

+1.2%

Avg return

Earnings day

-1.1%

Avg return

5 days after

+9.8%

Avg return

30 days after

40%

6 / 15 earnings

Positive

+14.8%

Q4 2024

Best reaction

-11.6%

Q3 2023

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2026-2.6%-2.5%-29.1%
Q3 2025-2.0%+7.3%+3.3%
Q1 2025-4.6%-11.2%-21.2%
Q4 2024+14.8%+13.1%-0.6%
Q3 2024+1.9%-14.1%-15.5%
Q2 2024-0.8%+0.9%+8.6%
Q1 2024-8.7%-9.0%+35.3%
Q4 2023-2.5%-5.9%+15.1%
Q3 2022+11.5%+7.1%+23.4%
Q3 2023-11.6%-1.6%+7.2%
Q2 2023-1.9%-2.9%-0.1%
Q2 2022-1.9%-2.9%-0.1%
Q1 2023+8.9%+1.9%+40.2%
Q4 2022+8.9%+1.9%+40.2%
Q1 2022+8.9%+1.9%+40.2%
Q4 2021

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