NASDAQ$GHRS

GH Research PLC · Q4 2025 earnings

Q4 2025 earnings · · Investor relations

Briefing

GH Research reported Q4 2025 revenue of $12.0M, a net loss of $28.0M, diluted EPS of $-0.55.

For Q4 2025, GH Research reported Revenue was $12.0M, net loss was $28.0M, diluted EPS was $-0.55. Management discusses segment trends, liquidity, and outlook in the quarterly filing.

  • Revenue $12.0M for Q4 2025.
  • Net loss $28.0M.
  • Diluted EPS $-0.55.

Headline financials

Total Revenue

$12M

Previous: $0.00
EPS (adj)

-$0.55

Previous: -$0.17-223.5%
MADRS Reduction

-15.5

No prior period
Remission Rate Day 8

57.5%

No prior period
R&D Expenses

$38.8M

No prior period
G&A Expenses

$22M

No prior period
6-Month Remission Rate

73.0%

No prior period
Net Income

-$28M

Previous: -$8.8M-218.1%
Operating Income

$0.00

Previous: -$12.9M+100.0%

Revenue & EPS history

GH Research · Revenue · Quarterly

$12M

Q4 2025

Forward guidance

Outlook emphasizes path to profitability, liquidity, and cost discipline.

Tailwinds

  • Restructuring and operating initiatives.
  • Cash runway and strategic partnerships.

Headwinds

  • Operating losses and financing needs.
  • Demand and competitive uncertainty.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 10 quarterly earnings reports · overlaid with Q4 2025

Historical avgQ4 2025

+0.7%

Avg return

Earnings day

+1.4%

Avg return

5 days after

+0.3%

Avg return

30 days after

55%

6 / 11 earnings

Positive

+24.4%

Q3 2021

Best reaction

-19.3%

Q2 2024

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+1.3%+0.2%-3.7%
Q3 2025-1.2%+4.6%+9.6%
Q4 2025-4.8%-10.2%-21.6%
Q2 2025+2.2%+10.2%+19.3%
Q4 2024-2.9%-14.4%+0.8%
Q2 2024-19.3%-21.6%-37.8%
Q1 2024+4.5%+7.1%+25.9%
Q2 2023-5.8%+1.2%-5.0%
Q1 2023+8.2%+6.9%+24.6%
Q4 2021+1.1%+7.5%-15.6%
Q3 2021+24.4%+24.4%+7.1%
Q1 2021
Q4 2020
Q3 2020
Q2 2020
Q1 2020

Discussion

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