NASDAQ$FOLD
Amicus Therapeutics Inc · Q4 2024 earnings
Q4 2024 earnings · · Before market open · Investor relations
Briefing
Amicus Therapeutics reported strong revenue growth in Q4 2024, driven by Galafold and Pombiliti + Opfolda sales.
Amicus Therapeutics reported Q4 2024 revenue of $149.7 million, a 30% increase year-over-year. Net income for the quarter was $14.7 million, a significant improvement from a loss of $33.8 million in Q4 2023. Non-GAAP net income was $29.2 million, with a non-GAAP EPS of $0.10. The company continues to expand its commercial presence for Pombiliti + Opfolda and anticipates achieving positive GAAP net income during H2 2025.
- Q4 2024 revenue grew 30% YoY to $149.7 million.
- Galafold sales increased by 20% to $127.5 million in Q4.
- Pombiliti + Opfolda sales surged 162% YoY, reaching $22.2 million.
- Q4 GAAP net income was $14.7 million, reversing a prior-year loss.
Headline financials
Revenue & EPS history
Amicus Therapeutics · Revenue · Quarterly
$150M
Revenue by segment
Amicus Therapeutics · $100M total across 1 segment · Q3 2023
- Galafold$100M—100.0%
Forward guidance
Amicus Therapeutics projects total revenue growth of 17% to 24% in 2025, with continued expansion in Pombiliti + Opfolda sales and positive GAAP net income expected in the second half of 2025.
Tailwinds
- Total revenue projected to grow 17% to 24% in 2025.
- Galafold revenue expected to increase 10% to 15%.
- Pombiliti + Opfolda growth forecasted between 65% and 85%.
- Company aims to surpass $1 billion in revenue by 2028.
- Continued expansion in international markets with new regulatory approvals.
Headwinds
- Operating expenses projected between $350M and $370M in 2025.
- Potential risks related to pricing and reimbursement negotiations.
- Market conditions and foreign exchange impacts may affect revenue.
- Increased competition in the rare disease treatment market.
- Regulatory approval timelines may impact commercialization strategy.
Historical earnings impact
How earnings announcements have historically affected this stock's price.
Avg. return before/after earnings
Based on 20 quarterly earnings reports · overlaid with Q4 2024
-0.3%
Avg return
Earnings day
+0.9%
Avg return
5 days after
+1.3%
Avg return
30 days after
39%
25 / 64 earnings
Positive
+28.4%
Q3 2016
Best reaction
-16.1%
Q2 2015
Worst reaction
| Quarter | Report date | Reaction (Day 0) | +5 days | +30 days |
|---|---|---|---|---|
| Q4 2025 | +0.2% | +0.0% | +0.6% | |
| Q3 2025 | +1.6% | +0.1% | +12.3% | |
| Q2 2025 | -2.5% | +14.0% | +23.8% | |
| Q1 2025 | -13.0% | -19.4% | -21.0% | |
| Q4 2024 | -2.9% | -5.2% | -8.5% | |
| Q3 2024 | -6.5% | -8.9% | -17.1% | |
| Q2 2024 | +14.8% | +17.2% | +16.5% | |
| Q1 2024 | -9.0% | -8.0% | -0.9% | |
| Q4 2023 | -7.4% | -2.8% | -14.9% | |
| Q3 2023 | -14.8% | -12.3% | -4.2% | |
| Q2 2023 | +9.1% | +7.0% | -1.4% | |
| Q1 2023 | -4.2% | -8.1% | +5.1% | |
| Q4 2022 | -3.9% | -8.1% | -15.9% | |
| Q3 2022 | +6.5% | +11.1% | +20.5% | |
| Q2 2022 | +17.5% | +19.2% | +10.5% | |
| Q1 2022 | +7.5% | +19.5% | +40.0% | |
| Q4 2021 | +0.0% | -0.5% | +13.2% | |
| Q3 2021 | -3.8% | -4.9% | -12.6% | |
| Q2 2021 | +8.5% | +7.6% | +20.1% | |
| Q1 2021 | -1.5% | -2.7% | +8.5% | |
| Q4 2020 | -9.0% | -14.7% | -19.5% | |
| Q3 2020 | -1.3% | +7.5% | +11.8% | |
| Q2 2020 | -5.3% | -6.6% | -9.5% | |
| Q1 2020 | -1.6% | +2.5% | +8.7% | |
| Q4 2019 | -4.2% | -0.6% | -7.2% | |
| Q3 2019 | +3.2% | +7.0% | +5.8% | |
| Q2 2019 | -8.5% | -12.0% | -21.9% | |
| Q1 2019 | -4.8% | -11.7% | -13.2% | |
| Q4 2018 | +12.0% | +9.1% | +9.4% | |
| Q3 2018 | -6.0% | -10.6% | -16.3% | |
| Q2 2018 | +4.7% | +5.4% | -16.8% | |
| Q1 2018 | -4.7% | -4.0% | +11.2% | |
| Q4 2017 | -6.2% | -9.0% | -0.7% | |
| Q3 2017 | -10.4% | -8.5% | -6.6% | |
| Q2 2017 | +1.1% | -8.9% | +6.3% | |
| Q1 2017 | +1.2% | +8.4% | +27.3% | |
| Q4 2016 | +14.5% | +18.5% | +9.9% | |
| Q3 2016 | +28.4% | +49.8% | -4.6% | |
| Q2 2016 | -9.5% | +0.0% | +1.4% | |
| Q1 2016 | -9.6% | — | — | |
| Q4 2015 | -4.3% | — | — | |
| Q3 2015 | +8.9% | — | — | |
| Q2 2015 | -16.1% | — | — | |
| Q1 2015 | -1.5% | — | — | |
| Q4 2014 | -0.5% | — | — | |
| Q3 2014 | -0.5% | — | — | |
| Q2 2014 | -2.8% | — | — | |
| Q1 2014 | +0.5% | — | — | |
| Q4 2013 | +2.8% | — | — | |
| Q3 2013 | +3.9% | — | — | |
| Q2 2013 | +7.8% | — | — | |
| Q1 2013 | -1.3% | — | — | |
| Q4 2012 | +11.0% | — | — | |
| Q3 2012 | -13.3% | — | — | |
| Q2 2012 | -5.5% | — | — | |
| Q1 2012 | +6.4% | — | — | |
| Q4 2011 | -4.9% | — | — | |
| Q3 2011 | +3.9% | — | — | |
| Q2 2011 | +6.7% | — | — | |
| Q1 2011 | -1.1% | — | — | |
| Q4 2010 | -4.4% | — | — | |
| Q3 2010 | -2.5% | — | — | |
| Q2 2010 | +10.0% | — | — | |
| Q1 2010 | -1.3% | — | — |
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