NASDAQ$ERAS

Erasca Inc · Q4 2021 earnings

Q4 2021 earnings · · Investor relations

Briefing

Reported financial results for the fourth quarter of 2021 and provided business updates.

Erasca reported its Q4 2021 financial results, highlighting a strong cash position of $459.2 million and progress in its clinical programs, including ERAS-007, ERAS-601, and ERAS-801.

  • Initiated three HERKULES clinical trials in 2021 evaluating ERAS-007.
  • Entered into a clinical trial collaboration and supply agreement with Lilly for cetuximab.
  • Nominated ERAS-3490, a highly CNS-penetrant KRAS G12C inhibitor.
  • Received IND clearance of ERAS-801 for the treatment of patients with recurrent glioblastoma multiforme.

Headline financials

EPS (adj)

-$0.26

Previous: -$2.70+90.4%
Capital Expenditures

$5.83M

No prior period
Free Cash Flow

-$28.3M

No prior period
Net Income

-$30.5M

Previous: -$61.9M+50.8%
Operating Income

-$31M

Previous: -$67M+53.6%
Cash & Equivalents

$459M

No prior period
Total Assets

$501M

No prior period
Stock-Based Comp

$2.88M

No prior period

Revenue & EPS history

Erasca · Revenue · Quarterly

$0

Q3 2025-100%vs Q3 2024

Forward guidance

Erasca expects its current cash, cash equivalents, and investments balance to fund operations into 2024.

Tailwinds

  • Potential therapeutic benefits of product candidates, including ERAS-007, ERAS-601, ERAS-801, and ERAS-3490.
  • Expected timing of the IND filing for ERAS-3490.
  • Ability to continue to successfully execute on the business plan in 2022.
  • Planned advancement of the development pipeline.
  • Anticipated timing of data readouts for clinical trials and other upcoming development milestones.

Headwinds

  • Approach to the discovery and development of product candidates based on a singular focus on shutting down the RAS/MAPK pathway.
  • Potential delays in the commencement, enrollment, and completion of clinical trials and preclinical studies.
  • Dependence on third parties in connection with manufacturing, research, and preclinical and clinical testing.
  • Unexpected adverse side effects or inadequate efficacy of product candidates.
  • Inability to realize any benefits from current licenses and acquisitions and any future licenses, acquisitions, or collaborations.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 17 quarterly earnings reports · overlaid with Q4 2021

Historical avgQ4 2021

+1.1%

Avg return

Earnings day

+1.0%

Avg return

5 days after

+1.3%

Avg return

30 days after

58%

11 / 19 earnings

Positive

+11.0%

Q3 2022

Best reaction

-10.1%

Q1 2024

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+3.3%+1.0%+32.1%
Q4 2025-4.3%-7.8%+16.1%
Q3 2025-4.2%+7.9%+35.8%
Q1 2025-4.0%-5.8%+9.3%
Q4 2024+6.0%-8.2%+25.0%
Q3 2024-8.4%-14.1%-15.4%
Q2 2024+8.3%+16.7%+27.9%
Q1 2024-10.1%-12.8%+8.9%
Q4 2023+4.0%+9.1%-4.5%
Q3 2023-8.6%-1.8%-15.0%
Q2 2023+10.6%-3.2%-0.8%
Q1 2023-1.0%-3.8%-5.6%
Q4 2022-2.7%-5.8%-3.8%
Q3 2022+11.0%+20.7%-19.1%
Q2 2022+2.5%+4.4%-10.8%
Q1 2022+2.8%+9.4%-4.6%
Q4 2021+9.1%+8.1%-9.7%
Q3 2021+2.2%-3.1%-28.9%
Q2 2021+4.8%+8.9%-12.3%
Q1 2021
Q4 2020
Q3 2020
Q2 2020
Q1 2020

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