NASDAQ$DSGN

Design Therapeutics Inc · Q2 2022 earnings

Q2 2022 earnings · · Investor relations

Briefing

Reported second quarter 2022 financial results and highlighted upcoming milestones.

Design Therapeutics reported a net loss of $15.0 million for the second quarter of 2022 and holds a strong financial position with $359.4 million in cash and securities. The company is advancing its pipeline, with initial data from the Friedreich Ataxia Phase 1 trial expected in the fourth quarter of 2022.

  • Initial data from the Friedreich Ataxia Phase 1 trial of DT-216 is expected in the fourth quarter of 2022.
  • The company's GeneTAC™ program for myotonic dystrophy type-1 (DM1) has advanced.
  • Compelling preclinical data was announced in Fuchs endothelial corneal dystrophy (FECD).
  • Cash, cash equivalents and marketable securities were $359.4 million as of June 30, 2022, supporting a multi-year operating runway.

Headline financials

EPS (adj)

-$0.27

Previous: -$0.14-92.9%
Capital Expenditures

$244K

Previous: -$216K+213.0%
Free Cash Flow

-$10.7M

Previous: -$7.85M-36.8%
Net Income

-$15M

Previous: -$7.64M-96.4%
Operating Income

-$15.6M

Previous: -$7.69M-103.4%
Cash & Equivalents

$359M

Previous: $403M-10.8%
Total Assets

$368M

Previous: $405M-9.2%
Stock-Based Comp

$2.62M

Previous: $1.24M+110.5%

Revenue & EPS history

Design Therapeutics · Revenue · Quarterly

$0

Q1 2026

Forward guidance

Design Therapeutics anticipates several milestones, including initial data from the DT-216 Phase 1 trial, clinical development for the DM1 program, and advancing research in FECD.

Tailwinds

  • Initial data from the single-ascending dose portion of the Phase 1 trial for DT-216 is expected in the fourth quarter of 2022.
  • Clinical development for the DM1 program is anticipated in 2023.
  • Research in FECD is advancing throughout the second half of 2022.
  • Design's approach paves the way for disease-modifying treatments for patients with inherited genetic diseases.
  • The company is bringing forward a new class of treatments for patients living with devastating genetic diseases.

Headwinds

  • Clinical trial and patient enrollment are affected by many factors.
  • Difficulties or delays encountered with clinical trials may adversely affect Design’s ongoing Phase 1 clinical trial for DT-216.
  • Promising early research or clinical trials may not demonstrate safety and/or efficacy in later preclinical studies or clinical trials.
  • Changes in Design’s plans to develop its product candidates.
  • Reliance on third parties to successfully conduct clinical trials and preclinical studies.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 19 quarterly earnings reports · overlaid with Q2 2022

Historical avgQ2 2022

-2.2%

Avg return

Earnings day

+1.7%

Avg return

5 days after

+3.2%

Avg return

30 days after

50%

10 / 20 earnings

Positive

+15.1%

Q4 2023

Best reaction

-71.7%

Q2 2023

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+0.0%+3.8%-16.2%
Q4 2025+3.2%+0.7%+26.1%
Q3 2025+10.7%+10.8%+42.2%
Q2 2025-8.9%+14.5%+48.3%
Q1 2025+0.3%+10.3%+10.3%
Q4 2024+0.4%+2.5%-27.2%
Q3 2024-1.9%+16.3%+7.9%
Q1 2024+1.7%-3.0%-17.9%
Q4 2023+15.1%+50.8%+48.4%
Q3 2023+13.9%+10.4%+27.4%
Q2 2023-71.7%-72.8%-65.2%
Q1 2023-12.2%-12.6%-26.4%
Q4 2022-0.6%-8.1%-24.8%
Q3 2022-0.3%-0.8%-9.7%
Q2 2022+0.3%+13.5%+5.5%
Q1 2022-1.5%-2.4%+30.9%
Q4 2021-1.8%-0.8%-10.0%
Q3 2021+4.8%+10.7%-3.8%
Q2 2021+9.9%+7.9%+19.7%
Q1 2021-6.0%-18.0%-1.8%
Q4 2020
Q3 2020
Q2 2020
Q1 2020

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