NASDAQ$DSGN
Design Therapeutics Inc · Q1 2024 earnings
Q1 2024 earnings · · Investor relations
Briefing
Design Therapeutics announced first quarter 2024 financial results, highlighting progress in advancing DT-216P2 for Friedreich Ataxia (FA) towards clinical trials, starting Phase 1 development for Fuchs Endothelial Corneal Dystrophy (FECD) in 2024, and progressing GeneTAC™ pipeline programs in Huntington’s Disease (HD) and Myotonic Dystrophy Type-1 (DM1) to development candidates.
Design Therapeutics reported a net loss of $11.1 million for the first quarter of 2024. The company's cash and securities totaled $270.7 million, expected to fund operations into 2029. Key programs in FA, FECD, HD, and DM1 are advancing, with potential for clinical proof-of-concept.
- Advancing DT-216P2, a new drug product for Friedreich Ataxia (FA), toward clinical trials.
- Starting Phase 1 development for Fuchs Endothelial Corneal Dystrophy (FECD) in 2024; observational study currently enrolling patients.
- Progressing GeneTAC™ pipeline programs in Huntington’s Disease (HD) and Myotonic Dystrophy Type-1 (DM1) to development candidates.
- Cash and securities of $270.7 million support a multi-year operating runway and advancement of up to four programs to clinical proof-of-concept.
Headline financials
Revenue & EPS history
Design Therapeutics · Revenue · Quarterly
$0
Forward guidance
Design Therapeutics is focused on advancing its portfolio of therapies for genetic disorders, with key milestones expected in FA and FECD programs. The company anticipates completing GLP studies for DT-216P2 by year-end 2024 and initiating Phase 1 development for DT-168 in 2024. Preclinical characterization is ongoing for HD and DM1 programs.
Tailwinds
- On track to complete GLP studies for DT-216P2 by year-end 2024 to start patient trials in 2025.
- Expects to initiate Phase 1 development for DT-168 in 2024.
- Advancing preclinical characterization of lead molecules for Huntington’s disease (HD) and myotonic dystrophy type-1 (DM1).
- Cash position expected to fund planned operating expenses into 2029.
- Demonstrates an improved pharmacokinetic profile with DT-216P2.
Headwinds
- The company reported a net loss of $11.1 million for the quarter ended March 31, 2024.
- Advancement of programs is subject to R&D results.
- Clinical trials and regulatory filings are subject to inherent risks and uncertainties.
- Success depends on demonstrating safety and efficacy in clinical trials.
- Market conditions and competition could impact the company's prospects.
Historical earnings impact
How earnings announcements have historically affected this stock's price.
Avg. return before/after earnings
Based on 19 quarterly earnings reports · overlaid with Q1 2024
-2.2%
Avg return
Earnings day
+1.7%
Avg return
5 days after
+3.2%
Avg return
30 days after
50%
10 / 20 earnings
Positive
+15.1%
Q4 2023
Best reaction
-71.7%
Q2 2023
Worst reaction
| Quarter | Report date | Reaction (Day 0) | +5 days | +30 days |
|---|---|---|---|---|
| Q1 2026 | +0.0% | +3.8% | -16.2% | |
| Q4 2025 | +3.2% | +0.7% | +26.1% | |
| Q3 2025 | +10.7% | +10.8% | +42.2% | |
| Q2 2025 | -8.9% | +14.5% | +48.3% | |
| Q1 2025 | +0.3% | +10.3% | +10.3% | |
| Q4 2024 | +0.4% | +2.5% | -27.2% | |
| Q3 2024 | -1.9% | +16.3% | +7.9% | |
| Q1 2024 | +1.7% | -3.0% | -17.9% | |
| Q4 2023 | +15.1% | +50.8% | +48.4% | |
| Q3 2023 | +13.9% | +10.4% | +27.4% | |
| Q2 2023 | -71.7% | -72.8% | -65.2% | |
| Q1 2023 | -12.2% | -12.6% | -26.4% | |
| Q4 2022 | -0.6% | -8.1% | -24.8% | |
| Q3 2022 | -0.3% | -0.8% | -9.7% | |
| Q2 2022 | +0.3% | +13.5% | +5.5% | |
| Q1 2022 | -1.5% | -2.4% | +30.9% | |
| Q4 2021 | -1.8% | -0.8% | -10.0% | |
| Q3 2021 | +4.8% | +10.7% | -3.8% | |
| Q2 2021 | +9.9% | +7.9% | +19.7% | |
| Q1 2021 | -6.0% | -18.0% | -1.8% | |
| Q4 2020 | — | — | — | |
| Q3 2020 | — | — | — | |
| Q2 2020 | — | — | — | |
| Q1 2020 | — | — | — |
Discussion
Share your read of this quarter. Sign-in carries your eToro identity.
Join the conversation
Sign in with eToro to post your read of this quarter and vote on others'.
Sign in with eToro