NASDAQ$CYPH

Cypherpunk Technologies Inc · Q4 2022 earnings

Q4 2022 earnings · · Investor relations

Briefing

Reported financial results for the fourth quarter and year ended December 31, 2022.

Leap Therapeutics reported its Q4 2022 financial results, highlighting the advancement of DKN-01 into a randomized controlled clinical trial for gastric cancer and the acquisition of Flame Biosciences, which included FL-301 and approximately $50 million in cash.

  • Advanced DKN-01 into a randomized controlled clinical trial in gastric cancer.
  • Entered into the new indication of colorectal cancer for DKN-01.
  • Acquired Flame Biosciences, enhancing Leap’s pipeline and financial strength.
  • Focused on executing the development plan for DKN-01 in 2023.

Headline financials

EPS (adj)

-$1.10

Previous: -$1.00-10.0%
Net Income

-$12.1M

Previous: -$40.6M+70.2%
Operating Income

-$13.9M

Previous: -$40.6M+65.7%
Cash & Equivalents

$65.5M

Previous: $115M-43.0%
Total Assets

$70.4M

Previous: $118M-40.3%
Stock-Based Comp

$1.46M

Previous: $938K+55.3%

Revenue & EPS history

Leap Therapeutics · Revenue · Quarterly

$0

Q3 2025
Beat estimate in 2 of 3 quarters(67%)
ActualEstimate

Forward guidance

In 2023, the company is focused on completing enrollment in studies for DKN-01, presenting new data, and identifying a new strategic partner. The plan for Claudin18.2 and GDF15 programs is to generate additional preclinical data to differentiate these antibodies and to prepare for future clinical trials.

Tailwinds

  • Completing enrollment in Part C of the DisTinGuish study.
  • Completing enrollment in Part A of the DeFianCe study.
  • Presenting new data over the course of the year.
  • Identifying a new strategic partner as data is generated.
  • Generating additional preclinical data to differentiate Claudin18.2 and GDF15 antibodies.

Headwinds

  • Clinical trials may be delayed, adversely affected, or impacted by COVID-19, global conflict, or supply chain related issues
  • Exposure to inflation, currency rate and interest rate fluctuations, as well as fluctuations in the market price of Leap’s traded securities
  • Leap’s ability to successfully execute its clinical trials and the timing of enrollment in and cost of such clinical trials
  • Leap’s ability to successfully enter into new strategic partnerships for DKN-01 or any of its other programs
  • Whether Leap’s cash resources will be sufficient to fund Leap’s continuing operations and the newly acquired Flame operations, including the liabilities of Flame incurred in connection with the completion of the merger

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q4 2022

Historical avgQ4 2022

+11.8%

Avg return

Earnings day

+13.6%

Avg return

5 days after

+11.4%

Avg return

30 days after

50%

17 / 34 earnings

Positive

+389.9%

Q3 2025

Best reaction

-44.0%

Q3 2019

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q3 2025+389.9%+454.8%+228.8%
Q2 2025-28.3%-15.6%-11.8%
Q1 2025-2.5%-12.4%-0.5%
Q4 2024+16.9%-21.4%+3.1%
Q3 2024-11.1%-14.5%-9.2%
Q1 2024-1.1%-5.4%-22.1%
Q4 2023-0.5%+14.0%+35.7%
Q3 2023+13.0%+32.6%+128.3%
Q2 2023+7.6%-8.9%-28.4%
Q1 2023+17.1%+44.4%+44.4%
Q4 2022-12.1%-0.9%+11.5%
Q3 2022+12.0%-3.2%-17.7%
Q2 2022+10.0%-0.8%+30.0%
Q1 2022+34.6%+25.4%+10.0%
Q4 2021-8.6%+2.3%+0.0%
Q3 2021+0.4%+0.8%+2.9%
Q2 2021+0.6%+3.6%-12.0%
Q1 2021+9.5%+8.8%+21.6%
Q4 2020+7.9%+6.1%-21.1%
Q3 2020+0.6%-3.1%+21.4%
Q2 2020-3.1%+0.3%-5.6%
Q1 2020+0.0%+0.4%+3.1%
Q4 2019-4.1%-14.2%+20.3%
Q3 2019-44.0%-33.7%-29.7%
Q2 2019-8.9%-10.2%+2.5%
Q1 2019-1.6%-6.5%-0.6%
Q4 2018+10.7%+4.3%-9.1%
Q3 2018-8.8%-17.1%-26.8%
Q2 2018+2.1%+6.1%+8.7%
Q4 2017-1.4%+1.2%+30.8%
Q3 2017-2.1%+16.9%+9.2%
Q2 2017-5.6%+2.0%-6.2%
Q1 2017+8.6%+10.4%-8.9%
Q4 2016+4.0%-4.7%-16.2%
Q3 2016
Q2 2016
Q1 2016
Q4 2015
Q3 2015
Q2 2015
Q1 2015
Q4 2014
Q3 2014
Q2 2014
Q1 2014
Q4 2013
Q3 2013
Q2 2013
Q1 2013

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