NASDAQ$CTMX

CytomX Therapeutics Inc · Q2 2025 earnings

Q2 2025 earnings · · After market close

Briefing

CytomX Therapeutics Inc reported its financial results for the second quarter ended June 30, 2025.

The company recorded collaboration revenues of $18.7 million in Q2 2025, down from $25.1 million in the prior year quarter, primarily due to the completion of performance obligations under certain collaboration agreements. The company reported a net loss of $0.2 million and ended the quarter with $49.0 million in cash and cash equivalents and total assets of $175.1 million. Research and development expenses decreased significantly year-over-year following a restructuring completed earlier in the year.

  • Q2 2025 collaboration revenues totaled $18.7 million, driven primarily by the Bristol Myers Squibb and Astellas agreements.
  • Net loss narrowed to $0.2 million compared to a $6.5 million loss in Q2 2024, aided by lower operating expenses post-restructuring.
  • Cash and cash equivalents stood at $49.0 million at quarter end, supported by a May 2025 equity offering that raised $93.4 million.
  • The company continues to advance its clinical pipeline with CX-2051 and CX-801 in Phase 1 trials while maintaining multiple research collaborations.

Headline financials

Total Revenue

$18.7M

Previous: $25.1M-25.7%
EPS (adj)

$0.00

Previous: -$0.08+100.0%
Capital Expenditures

-$146K

Previous: -$211K+30.8%
Net Income

-$154K

Previous: -$6.53M+97.6%
Operating Income

-$1.29M

Previous: -$8.45M+84.8%
Cash & Equivalents

$49M

No prior period
Total Assets

$175M

No prior period

Revenue & EPS history

CytomX Therapeutics Inc · Revenue · Quarterly

$18.7M

Q2 2025-25.7%vs Q2 2024
Beat estimate in 3 of 3 quarters(100%)
ActualEstimate

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 19 quarterly earnings reports

Historical avg

+3.6%

Avg return

Earnings day

+1.6%

Avg return

5 days after

+2.5%

Avg return

30 days after

53%

16 / 30 earnings

Positive

+129.5%

Q1 2025

Best reaction

-19.3%

Q4 2025

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q2 2025
Q1 2026-3.4%-6.3%-27.8%
Q4 2025-19.3%-34.1%-27.6%
Q3 2025-0.5%-2.6%-6.2%
Q1 2025+129.5%+118.8%+203.9%
Q3 2024+0.0%+4.0%+18.0%
Q2 2024+1.7%+0.0%+3.4%
Q1 2024+2.9%-53.6%-59.7%
Q3 2023+0.8%-7.9%+15.0%
Q2 2023-0.6%-1.2%-18.8%
Q1 2023+2.4%+6.0%+3.6%
Q3 2022-1.6%+3.2%+29.6%
Q2 2022+3.8%+1.9%-7.0%
Q1 2022-5.8%+4.1%+4.1%
Q3 2021-2.0%+14.8%+8.4%
Q2 2021+3.8%-12.0%-7.9%
Q1 2021-4.5%-4.5%-20.6%
Q3 2020+0.0%+5.7%+4.7%
Q2 2020+1.3%-6.2%-11.9%
Q1 2020+1.7%+21.5%-33.1%
Q3 2019+0.8%-9.8%+3.1%
Q2 2019+2.6%-7.3%-19.9%
Q1 2019-0.1%+7.2%+3.4%
Q3 2018-8.8%+7.3%-1.1%
Q2 2018+1.6%-4.2%-19.4%
Q1 2018+0.9%-3.6%+2.2%
Q3 2017-1.7%-1.4%+0.4%
Q2 2017+0.2%+2.6%+23.1%
Q1 2017+2.3%-0.2%-2.3%
Q3 2016-2.8%-5.7%-2.3%
Q2 2016+3.2%+10.8%+19.0%

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