NASDAQ$CTMX

CytomX Therapeutics Inc · Q1 2026 earnings

Q1 2026 earnings ·

Briefing

CytomX reported Q1 2026 revenue of $10.3M (-80% YoY) with a net loss of $18.2M, or $0.10 per share.

For the quarter ended March 31, 2026, CytomX reported revenues of $10.3 million versus $50.9 million a year ago as collaboration revenue declined. Net loss attributable to common stockholders was $18.2 million, or $0.10 per share, compared with net income of $23.5 million, or $0.27 per share, in Q1 2025.

  • Revenue $10.3M on lower collaboration milestones.
  • Net loss $(18.2)M vs prior-year profit.
  • R&D expense $19.2M.
  • Cash runway focus for pipeline.

Headline financials

Total Revenue

$10.3M

Previous: $50.9M-79.9%
EPS (adj)

-$0.10

Previous: $0.27-137.0%
Capital Expenditures

$0.00

Previous: -$119K+100.0%
Net Income

-$18.2M

Previous: $23.5M-177.6%

Revenue & EPS history

CytomX Therapeutics Inc · Revenue · Quarterly

$10.3M

Q1 2026-79.9%vs Q1 2025
Beat estimate in 2 of 2 quarters(100%)
ActualEstimate

Forward guidance

Clinical-stage biotech discusses partnerships and trial timelines; no product revenue guidance.

Tailwinds

  • Lower burn vs prior profitable quarter anomaly.
  • Partnership pipeline.

Headwinds

  • Revenue collapse vs milestone-heavy prior year.
  • Operating loss from R&D.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q1 2026

Historical avgQ1 2026

+3.6%

Avg return

Earnings day

+1.6%

Avg return

5 days after

+2.5%

Avg return

30 days after

53%

16 / 30 earnings

Positive

+129.5%

Q1 2025

Best reaction

-19.3%

Q4 2025

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-3.4%-6.3%-27.8%
Q4 2025-19.3%-34.1%-27.6%
Q3 2025-0.5%-2.6%-6.2%
Q1 2025+129.5%+118.8%+203.9%
Q3 2024+0.0%+4.0%+18.0%
Q2 2024+1.7%+0.0%+3.4%
Q1 2024+2.9%-53.6%-59.7%
Q3 2023+0.8%-7.9%+15.0%
Q2 2023-0.6%-1.2%-18.8%
Q1 2023+2.4%+6.0%+3.6%
Q3 2022-1.6%+3.2%+29.6%
Q2 2022+3.8%+1.9%-7.0%
Q1 2022-5.8%+4.1%+4.1%
Q3 2021-2.0%+14.8%+8.4%
Q2 2021+3.8%-12.0%-7.9%
Q1 2021-4.5%-4.5%-20.6%
Q3 2020+0.0%+5.7%+4.7%
Q2 2020+1.3%-6.2%-11.9%
Q1 2020+1.7%+21.5%-33.1%
Q3 2019+0.8%-9.8%+3.1%
Q2 2019+2.6%-7.3%-19.9%
Q1 2019-0.1%+7.2%+3.4%
Q3 2018-8.8%+7.3%-1.1%
Q2 2018+1.6%-4.2%-19.4%
Q1 2018+0.9%-3.6%+2.2%
Q3 2017-1.7%-1.4%+0.4%
Q2 2017+0.2%+2.6%+23.1%
Q1 2017+2.3%-0.2%-2.3%
Q3 2016-2.8%-5.7%-2.3%
Q2 2016+3.2%+10.8%+19.0%

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