NASDAQ$CRNX

Crinetics Pharmaceuticals Inc · Q3 2025 earnings

Q3 2025 earnings · · After market close · Investor relations

Briefing

CRNX reported Q3 2025 revenue of $143.0M, a net loss of $130.1M, diluted EPS of $-1.38.

For Q3 2025, CRNX reported Revenue was $143.0M, net loss was $130.1M, diluted EPS was $-1.38. The filing discusses operating performance, liquidity, and outlook in MD&A.

  • Revenue $143.0M for Q3 2025.
  • Net loss $130.1M.
  • Diluted EPS $-1.38.

Headline financials

Total Revenue

$143K

Previous: $0.00
EPS (adj)

-$1.38

Previous: -$0.96-43.7%
Capital Expenditures

-$5.3M

Previous: -$2.82M-88.4%
Free Cash Flow

-$135M

Previous: -$79.6M-70.0%
Net Income

-$130M

Previous: -$76.8M-69.3%
Operating Income

-$143M

Previous: -$87.8M-62.4%

Revenue & EPS history

Crinetics · Revenue · Quarterly

$143K

Q3 2025
Beat estimate in 9 of 15 quarters(60%)
ActualEstimate

Revenue by segment

Crinetics · $1.1M total across 1 segment · Q4 2021

  • Collaboration and license
    $1.1M

Forward guidance

Outlook focuses on cash runway, pipeline milestones, and cost discipline as the company works toward profitability.

Tailwinds

  • Cash and equivalents support operations into upcoming milestones.
  • Strategic initiatives and partnerships noted in MD&A.

Headwinds

  • Ongoing operating losses and R&D or interest spend pressure earnings.
  • Financing, dilution, or macro factors may affect liquidity.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q3 2025

Historical avgQ3 2025

+1.1%

Avg return

Earnings day

+1.4%

Avg return

5 days after

-1.0%

Avg return

30 days after

45%

14 / 31 earnings

Positive

+14.8%

Q2 2020

Best reaction

-13.0%

Q4 2019

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+4.3%-11.5%-21.1%
Q4 2025-6.1%-9.7%-23.0%
Q3 2025-8.0%-1.5%+7.3%
Q1 2025-6.2%-4.3%+0.9%
Q4 2024+7.7%+2.2%+4.6%
Q3 2024-1.8%-8.8%-7.3%
Q2 2024-1.4%+4.2%+4.3%
Q1 2024-5.7%-3.0%-12.1%
Q4 2023+1.2%+7.5%+15.7%
Q3 2023-6.7%-11.7%+9.8%
Q2 2023-7.3%-8.3%-10.2%
Q1 2023+3.6%+9.4%+2.0%
Q4 2022+2.2%-0.3%-17.6%
Q3 2022-0.8%-3.0%-11.4%
Q2 2022+8.6%+4.3%+2.1%
Q1 2022+11.2%+26.2%+10.3%
Q4 2021+11.6%+25.3%+3.3%
Q3 2021+0.7%-0.8%-10.7%
Q2 2021+13.3%+31.9%+40.8%
Q1 2021-0.7%-3.2%-0.8%
Q4 2020-0.7%+4.0%+15.4%
Q3 2020-7.8%-1.2%-2.6%
Q2 2020+14.8%+3.4%-5.3%
Q1 2020+14.3%+14.8%-5.8%
Q4 2019-13.0%-33.2%-33.1%
Q3 2019-0.4%-3.6%+13.3%
Q2 2019-4.5%-0.6%-8.1%
Q1 2019-2.3%+0.8%-12.8%
Q4 2018+8.1%+8.1%-0.3%
Q3 2018+8.8%+8.5%+27.9%
Q2 2018-2.9%-2.5%-7.2%
Q1 2018
Q4 2017
Q3 2017
Q2 2017
Q1 2017

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