NASDAQ$CRNX

Crinetics Pharmaceuticals Inc · Q2 2024 earnings

Q2 2024 earnings · · Investor relations

Briefing

Reported financial results for the second quarter ended June 30, 2024, and provided a business update.

Crinetics Pharmaceuticals reported a net loss of $74.1 million for Q2 2024, compared to a net loss of $51.0 million for the same period in 2023. Revenues were $0.4 million, down from $1.0 million in the prior year. The company's cash, cash equivalents, and investments totaled $863.0 million as of June 30, 2024.

  • Paltusotine NDA submission in Acromegaly is on track for 2024.
  • Topline results from Phase 2 studies of Atumelnant in Congenital Adrenal Hyperplasia and additional data for Phase 2 for ACTH-Dependent Cushing’s Syndrome are expected by the end of 2024.
  • Presented positive initial results from atumelnant studies at the Endocrine Society’s Annual Meeting (ENDO 2024).
  • Crinetics expects that its cash, cash equivalents and short-term investments will be sufficient to fund its current operating plan into 2028.

Headline financials

Total Revenue

$399K

Previous: $988K-59.6%
EPS

-$0.94

Previous: -$0.94+0.0%
Research and development

$58.3M

Previous: $40.6M+43.6%
Selling, general and administrative

$24.8M

Previous: $13.3M+86.5%
Cash, cash equivalents and investments

$863M

No prior period
Capital Expenditures

-$2.29M

Previous: -$253K-804.0%
Free Cash Flow

-$76.3M

Previous: -$51.2M-49.0%
Net Income

-$74.1M

Previous: -$51M-45.3%
Operating Income

-$82.8M

Previous: -$53M-56.2%
R&D Expense

$57.6M

No prior period
Stock-Based Comp

$18.9M

Previous: $10.2M+86.1%

Revenue & EPS history

Crinetics · Revenue · Quarterly

$399K

Q2 2024-59.6%vs Q2 2023
Beat estimate in 9 of 15 quarters(60%)
ActualEstimate

Revenue by segment

Crinetics · $1.1M total across 1 segment · Q4 2021

  • Collaboration and license
    $1.1M

Forward guidance

Crinetics anticipates several key milestones, including topline data from atumelnant studies, NDA submission for paltusotine, and initiation of a Phase 3 program for paltusotine in carcinoid syndrome.

Tailwinds

  • Topline data and additional data from the ongoing Phase 2 studies of atumelnant in CAH and ACTH dependent Cushing’s syndrome, respectively, are anticipated by the end of 2024.
  • Submission of a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) seeking regulatory approval of paltusotine for the treatment of acromegaly is on track for the second half of 2024.
  • Initiation of a Phase 3 program of paltusotine for carcinoid syndrome is expected by the end of 2024, following consultation with the FDA.
  • Additional research pipeline updates are expected by the end of 2024.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q2 2024

Historical avgQ2 2024

+1.1%

Avg return

Earnings day

+1.4%

Avg return

5 days after

-1.0%

Avg return

30 days after

45%

14 / 31 earnings

Positive

+14.8%

Q2 2020

Best reaction

-13.0%

Q4 2019

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+4.3%-11.5%-21.1%
Q4 2025-6.1%-9.7%-23.0%
Q3 2025-8.0%-1.5%+7.3%
Q1 2025-6.2%-4.3%+0.9%
Q4 2024+7.7%+2.2%+4.6%
Q3 2024-1.8%-8.8%-7.3%
Q2 2024-1.4%+4.2%+4.3%
Q1 2024-5.7%-3.0%-12.1%
Q4 2023+1.2%+7.5%+15.7%
Q3 2023-6.7%-11.7%+9.8%
Q2 2023-7.3%-8.3%-10.2%
Q1 2023+3.6%+9.4%+2.0%
Q4 2022+2.2%-0.3%-17.6%
Q3 2022-0.8%-3.0%-11.4%
Q2 2022+8.6%+4.3%+2.1%
Q1 2022+11.2%+26.2%+10.3%
Q4 2021+11.6%+25.3%+3.3%
Q3 2021+0.7%-0.8%-10.7%
Q2 2021+13.3%+31.9%+40.8%
Q1 2021-0.7%-3.2%-0.8%
Q4 2020-0.7%+4.0%+15.4%
Q3 2020-7.8%-1.2%-2.6%
Q2 2020+14.8%+3.4%-5.3%
Q1 2020+14.3%+14.8%-5.8%
Q4 2019-13.0%-33.2%-33.1%
Q3 2019-0.4%-3.6%+13.3%
Q2 2019-4.5%-0.6%-8.1%
Q1 2019-2.3%+0.8%-12.8%
Q4 2018+8.1%+8.1%-0.3%
Q3 2018+8.8%+8.5%+27.9%
Q2 2018-2.9%-2.5%-7.2%
Q1 2018
Q4 2017
Q3 2017
Q2 2017
Q1 2017

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