NASDAQ$CPRX
Catalyst Pharmaceuticals Inc · Q2 2025 earnings
Q2 2025 earnings · · After market close · Investor relations
Briefing
Catalyst Pharmaceuticals reported record financial results for the second quarter and first half of 2025, driven by strong product revenue growth across its portfolio.
Catalyst Pharmaceuticals achieved record total revenues in Q2 2025, reaching $146.6 million, a 19.4% increase year-over-year. This growth was primarily fueled by strong performances from FIRDAPSE and AGAMREE, with AGAMREE showing exceptional triple-digit growth. The company also maintained a strong cash position with $652.8 million and no funded debt.
- Record Q2 2025 total revenues of $146.6 million, up 19.4% year-over-year.
- AGAMREE net product revenue surged by 212.9% year-over-year to $27.4 million, driven by accelerating physician adoption.
- FIRDAPSE net product revenue increased by 9.7% year-over-year to $84.8 million, despite a one-time timing anomaly.
- Maintained a strong financial position with $652.8 million in cash and cash equivalents and no funded debt.
Headline financials
Revenue & EPS history
Catalyst Pharmaceuticals · Revenue · Quarterly
$147M
Revenue by segment
Catalyst Pharmaceuticals · $153M total across 3 segments · Q4 2025
- FIRDAPSE$97.6M+18.3%64.0%
- AGAMREE$35.3M+67.5%23.1%
- FYCOMPA$19.6M-48.7%12.9%
Forward guidance
Catalyst Pharmaceuticals reaffirmed its full-year 2025 total revenue guidance, expecting broad-based growth and sustained demand, despite anticipated impacts from generic competition for FYCOMPA.
Tailwinds
- Reaffirmed full-year 2025 total revenue guidance of $545 million to $565 million.
- Guidance reflects broad-based growth and sustained demand across the portfolio.
- Company is well-positioned to achieve 2025 guidance due to portfolio momentum and disciplined execution.
- Continued confidence in delivering value for patients, providers, and stakeholders.
- Strategic realignment of commercial teams for FIRDAPSE and AGAMREE expected to drive scalable growth.
Headwinds
- FYCOMPA net product revenue experienced a slight decrease year-over-year due to generic entry.
- Generic competition for FYCOMPA tablets is expected to impact net revenue going forward.
- Oral suspension exclusivity for FYCOMPA remains only until mid-December 2025.
- Royalty percentages and sales-based milestone obligations related to AGAMREE will increase as net sales grow.
- FYCOMPA royalties to the licensor will commence after the loss of patent protection, with tiered rates.
Historical earnings impact
How earnings announcements have historically affected this stock's price.
Avg. return before/after earnings
Based on 19 quarterly earnings reports · overlaid with Q2 2025
-0.7%
Avg return
Earnings day
+5.2%
Avg return
5 days after
+10.3%
Avg return
30 days after
38%
25 / 65 earnings
Positive
+29.1%
Q4 2016
Best reaction
-18.7%
Q1 2023
Worst reaction
| Quarter | Report date | Reaction (Day 0) | +5 days | +30 days |
|---|---|---|---|---|
| Q1 2026 | -0.0% | +0.1% | — | |
| Q4 2025 | +0.0% | -3.8% | -5.9% | |
| Q3 2025 | -1.9% | +8.0% | +10.1% | |
| Q2 2025 | -10.1% | -6.7% | -6.9% | |
| Q1 2025 | -3.0% | +0.8% | +10.3% | |
| Q4 2024 | +5.2% | +7.4% | +20.0% | |
| Q3 2024 | +5.9% | +6.8% | +0.3% | |
| Q2 2024 | +13.0% | +19.2% | +21.1% | |
| Q1 2024 | +3.4% | +7.1% | +3.2% | |
| Q4 2023 | +11.7% | +16.3% | +11.1% | |
| Q3 2023 | -4.1% | -1.7% | +10.1% | |
| Q2 2023 | +4.8% | +3.7% | -11.1% | |
| Q1 2023 | -18.7% | -24.5% | -33.2% | |
| Q4 2022 | +6.1% | +10.4% | +19.1% | |
| Q3 2022 | +0.7% | +2.7% | +6.8% | |
| Q2 2022 | +20.8% | +27.9% | +40.3% | |
| Q1 2022 | -0.5% | +5.7% | +1.7% | |
| Q4 2021 | -2.0% | +4.1% | +11.5% | |
| Q3 2021 | +2.7% | +18.0% | +4.3% | |
| Q2 2021 | +2.2% | +4.0% | -12.9% | |
| Q1 2021 | -1.9% | +14.1% | +17.2% | |
| Q4 2020 | +6.7% | +12.3% | +14.7% | |
| Q3 2020 | +7.9% | +7.9% | +12.4% | |
| Q2 2020 | -17.5% | -14.3% | -21.7% | |
| Q1 2020 | -5.7% | -6.4% | -6.6% | |
| Q4 2019 | -15.2% | -13.5% | +27.6% | |
| Q3 2019 | -9.6% | -11.6% | -13.9% | |
| Q2 2019 | +0.6% | -1.0% | +30.7% | |
| Q1 2019 | -0.3% | +20.7% | +16.9% | |
| Q4 2018 | +16.8% | +34.9% | +76.5% | |
| Q3 2018 | -4.9% | -14.5% | -26.2% | |
| Q2 2018 | +2.4% | +3.8% | +16.1% | |
| Q1 2018 | +0.7% | +21.2% | +23.4% | |
| Q4 2017 | -9.6% | -10.5% | -18.5% | |
| Q3 2017 | -4.2% | -6.1% | +28.2% | |
| Q2 2017 | -1.4% | +1.4% | -9.7% | |
| Q1 2017 | +2.2% | +12.2% | +32.8% | |
| Q4 2016 | +29.1% | +41.9% | +50.4% | |
| Q3 2016 | +4.0% | +12.9% | +16.8% | |
| Q2 2016 | -1.3% | -3.9% | +33.8% | |
| Q1 2016 | -6.3% | — | — | |
| Q4 2015 | -10.6% | — | — | |
| Q3 2015 | -5.3% | — | — | |
| Q2 2015 | -9.2% | — | — | |
| Q1 2015 | -1.5% | — | — | |
| Q4 2014 | +15.8% | — | — | |
| Q3 2014 | -6.3% | — | — | |
| Q2 2014 | -2.7% | — | — | |
| Q1 2014 | +2.8% | — | — | |
| Q4 2013 | +9.6% | — | — | |
| Q3 2013 | -2.1% | — | — | |
| Q2 2013 | -6.3% | — | — | |
| Q1 2013 | -7.3% | — | — | |
| Q4 2012 | -5.1% | — | — | |
| Q3 2012 | -10.7% | — | — | |
| Q2 2012 | -7.9% | — | — | |
| Q1 2012 | -5.6% | — | — | |
| Q4 2011 | -6.1% | — | — | |
| Q3 2011 | +2.0% | — | — | |
| Q2 2011 | -6.6% | — | — | |
| Q1 2011 | -0.7% | — | — | |
| Q4 2010 | -0.0% | — | — | |
| Q3 2010 | -0.5% | — | — | |
| Q2 2010 | +0.3% | — | — | |
| Q1 2010 | -9.8% | — | — |
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