NASDAQ$COGT

Cogent Biosciences Inc · Q1 2025 earnings

Q1 2025 earnings · · Before market open · Investor relations

Briefing

Cogent Biosciences reported its first quarter 2025 financial results, highlighting progress in clinical trials and a strong cash position.

Cogent Biosciences reported a net loss of $72.0 million for the first quarter of 2025, an increase from $58.3 million in the same period last year. The company ended the quarter with $245.7 million in cash, cash equivalents, and marketable securities, which is expected to fund operations into late 2026, including key clinical trial readouts.

  • Net loss for Q1 2025 was $72.0 million, compared to $58.3 million for Q1 2024.
  • Cash, cash equivalents, and marketable securities totaled $245.7 million as of March 31, 2025.
  • Research and development expenses increased to $63.0 million in Q1 2025 from $52.7 million in Q1 2024, driven by ongoing clinical trials.
  • General and administrative expenses rose to $11.9 million in Q1 2025 from $9.7 million in Q1 2024 due to organizational growth.

Headline financials

Total Revenue

$0.00

Previous: $0.00
EPS (adj)

$0.00

Previous: -$0.62+100.0%
Working capital

$204M

Previous: $241M-15.5%
Total liabilities

$64.8M

Previous: $71.6M-9.5%
Stockholders’ equity

$219M

Previous: $256M-14.6%
R&D expenses

$63M

Previous: $52.7M+19.6%
G&A expenses

$11.9M

Previous: $9.7M+22.7%
Interest income

$2.95M

Previous: $4.06M-27.2%
Net Income

-$72M

Previous: -$58.3M-23.4%
Operating Income

-$74.9M

Previous: -$62.4M-20.1%

Revenue & EPS history

Cogent Biosciences · Revenue · Quarterly

$0

Q1 2025

Forward guidance

Cogent Biosciences anticipates significant clinical trial readouts in 2025 and expects its current cash reserves to fund operations into late 2026, supporting a potential launch of bezuclastinib in 2026.

Tailwinds

  • SUMMIT top-line results in NonAdvanced SM expected in July 2025.
  • APEX top-line results in Advanced SM expected in the second half of 2025.
  • PEAK top-line results in GIST expected by end of 2025.
  • Sufficient cash to fund operations into late 2026, including through clinical readouts.
  • Potential commercial launch of bezuclastinib in 2026.

Headwinds

  • Forward-looking statements are subject to risks and uncertainties, and actual results may differ.
  • No guarantee that forecasts or milestones will be achieved.
  • New risks and uncertainties may emerge over time.
  • The company does not undertake to publicly update or revise forward-looking statements.
  • Reliance on forward-looking statements should be limited to the date they were made.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q1 2025

Historical avgQ1 2025

+0.9%

Avg return

Earnings day

+0.3%

Avg return

5 days after

+4.5%

Avg return

30 days after

65%

20 / 31 earnings

Positive

+17.8%

Q3 2018

Best reaction

-24.0%

Q1 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+0.8%-5.3%-10.6%
Q3 2025-4.4%-9.1%+140.2%
Q2 2025-5.8%-9.0%+7.4%
Q1 2025+2.7%+4.4%+48.4%
Q4 2024-6.3%+0.9%-11.4%
Q3 2024+0.0%-14.4%-19.8%
Q1 2024+0.4%-0.1%+11.1%
Q4 2023+0.7%-2.8%-12.4%
Q3 2023+3.9%+3.8%-2.7%
Q2 2023+7.3%+8.8%+9.4%
Q1 2023-1.5%-2.6%-2.9%
Q4 2022+0.7%-5.1%-13.7%
Q3 2022-5.7%-8.5%-2.6%
Q2 2022+9.6%+12.1%+32.7%
Q1 2022-24.0%-26.8%-10.6%
Q4 2021+4.5%+28.4%+64.6%
Q3 2021+13.7%+12.1%-9.9%
Q2 2021+5.4%+13.4%+3.3%
Q1 2021+1.7%+4.9%+4.0%
Q4 2020+5.9%+5.5%+9.0%
Q3 2020+13.2%+9.8%+14.9%
Q2 2020-11.4%-11.0%-8.3%
Q1 2020+0.5%+17.9%+37.1%
Q4 2019-3.1%-15.5%-18.6%
Q3 2019-10.2%-32.6%-52.1%
Q2 2019+4.4%+9.3%+9.0%
Q1 2019+0.2%-1.1%-26.2%
Q4 2018+8.1%+5.4%-12.3%
Q3 2018+17.8%+18.5%-25.0%
Q2 2018-5.9%-12.8%-27.3%
Q1 2018+4.0%+12.4%+13.6%
Q4 2017
Q3 2017
Q2 2017
Q1 2017
Q3 2016
Q3 2015

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