NASDAQ$COGT
Cogent Biosciences Inc · Q1 2024 earnings
Q1 2024 earnings · · Investor relations
Briefing
Cogent Biosciences reported financial results for the first quarter of 2024 and provided a business update.
Cogent Biosciences reported first quarter results, highlighting progress in clinical trials for bezuclastinib and a strong cash position to fund operations into 2027. Enrollment in APEX and PEAK trials is expected to be completed by the end of the year, with SUMMIT enrollment in Q2 2025, and topline results from all three trials anticipated in 2025.
- SUMMIT trial showed positive Part 1b data with bezuclastinib in nonadvanced systemic mastocytosis patients, leading to the initiation of the registration-directed SUMMIT Part 2.
- Preclinical data for the company’s ErbB2 candidate (CGT4255) was presented, demonstrating exceptional stability, high oral bioavailability, and brain penetrance.
- An oversubscribed private placement was completed, resulting in $213.4 million net proceeds, extending the company’s cash runway into 2027.
- Enrollment remains on track for the SUMMIT, PEAK and APEX registration-directed clinical trials with topline results expected from all three studies in 2025.
Headline financials
Revenue & EPS history
Cogent Biosciences · Revenue · Quarterly
$0
Forward guidance
Cogent Biosciences anticipates several milestones including completion of enrollment for APEX and PEAK trials by the end of 2024, SUMMIT Part 2 in Q2 2025, presentation of PEAK trial data at ASCO, and expects its cash to fund operations into 2027.
Tailwinds
- Complete enrollment in APEX in patients with advanced systemic mastocytosis (AdvSM) by the end of 2024 and report top-line results mid-2025.
- Complete enrollment in SUMMIT Part 2 in the second quarter of 2025 and report top-line results by the end of 2025.
- Complete enrollment in PEAK in patients with Gastrointestinal Stromal Tumors (GIST) by the end of 2024 and report top-line results by the end of 2025.
- Share updated clinical data from the lead-in portion of PEAK at the American Society of Clinical Oncology (ASCO) annual meeting taking place May 31-June 4, 2024.
- Company expects its existing cash, cash equivalents and marketable securities will be sufficient to fund its operating expenses and capital expenditure requirements into 2027 and through clinical readouts from ongoing SUMMIT, PEAK, and APEX registration-directed trials.
Historical earnings impact
How earnings announcements have historically affected this stock's price.
Avg. return before/after earnings
Based on 20 quarterly earnings reports · overlaid with Q1 2024
+0.9%
Avg return
Earnings day
+0.3%
Avg return
5 days after
+4.5%
Avg return
30 days after
65%
20 / 31 earnings
Positive
+17.8%
Q3 2018
Best reaction
-24.0%
Q1 2022
Worst reaction
| Quarter | Report date | Reaction (Day 0) | +5 days | +30 days |
|---|---|---|---|---|
| Q1 2026 | +0.8% | -5.3% | -10.6% | |
| Q3 2025 | -4.4% | -9.1% | +140.2% | |
| Q2 2025 | -5.8% | -9.0% | +7.4% | |
| Q1 2025 | +2.7% | +4.4% | +48.4% | |
| Q4 2024 | -6.3% | +0.9% | -11.4% | |
| Q3 2024 | +0.0% | -14.4% | -19.8% | |
| Q1 2024 | +0.4% | -0.1% | +11.1% | |
| Q4 2023 | +0.7% | -2.8% | -12.4% | |
| Q3 2023 | +3.9% | +3.8% | -2.7% | |
| Q2 2023 | +7.3% | +8.8% | +9.4% | |
| Q1 2023 | -1.5% | -2.6% | -2.9% | |
| Q4 2022 | +0.7% | -5.1% | -13.7% | |
| Q3 2022 | -5.7% | -8.5% | -2.6% | |
| Q2 2022 | +9.6% | +12.1% | +32.7% | |
| Q1 2022 | -24.0% | -26.8% | -10.6% | |
| Q4 2021 | +4.5% | +28.4% | +64.6% | |
| Q3 2021 | +13.7% | +12.1% | -9.9% | |
| Q2 2021 | +5.4% | +13.4% | +3.3% | |
| Q1 2021 | +1.7% | +4.9% | +4.0% | |
| Q4 2020 | +5.9% | +5.5% | +9.0% | |
| Q3 2020 | +13.2% | +9.8% | +14.9% | |
| Q2 2020 | -11.4% | -11.0% | -8.3% | |
| Q1 2020 | +0.5% | +17.9% | +37.1% | |
| Q4 2019 | -3.1% | -15.5% | -18.6% | |
| Q3 2019 | -10.2% | -32.6% | -52.1% | |
| Q2 2019 | +4.4% | +9.3% | +9.0% | |
| Q1 2019 | +0.2% | -1.1% | -26.2% | |
| Q4 2018 | +8.1% | +5.4% | -12.3% | |
| Q3 2018 | +17.8% | +18.5% | -25.0% | |
| Q2 2018 | -5.9% | -12.8% | -27.3% | |
| Q1 2018 | +4.0% | +12.4% | +13.6% | |
| Q4 2017 | — | — | — | |
| Q3 2017 | — | — | — | |
| Q2 2017 | — | — | — | |
| Q1 2017 | — | — | — | |
| Q3 2016 | — | — | — | |
| Q3 2015 | — | — | — |
Discussion
Share your read of this quarter. Sign-in carries your eToro identity.
Join the conversation
Sign in with eToro to post your read of this quarter and vote on others'.
Sign in with eToro