NASDAQ$CNTA

Centessa Pharmaceuticals plc · Q3 2025 earnings

Q3 2025 earnings · · Before market open · Investor relations

Briefing

Centessa Pharmaceuticals reported Q3 2025, revenue of $15M, a net loss of $54.9M.

For Q3 2025, Centessa Pharmaceuticals reported revenue of $15M, a net loss of $54.9M. Management discussed operating trends, liquidity, and priorities as disclosed in the quarterly filing.

  • Revenue $15M.
  • Net loss $54.9M.
  • Centessa Pharmaceuticals updated strategic and capital priorities in the filing.

Headline financials

Total Revenue

$0.00

Previous: $263K-100.0%
EPS (adj)

$0.41

Previous: -$0.37+210.8%
Capital Expenditures

-$360K

Previous: -$34K-958.8%
Free Cash Flow

-$55.3M

Previous: -$42.6M-29.7%
Net Income

-$54.9M

Previous: -$42.6M-29.0%
Operating Income

-$53.8M

Previous: -$46.4M-15.9%
Gross Profit

$0.00

Previous: $263K-100.0%

Revenue & EPS history

Centessa · Revenue · Quarterly

$0

Q3 2025-100%vs Q3 2024
Beat estimate in 0 of 1 quarters(0%)
ActualEstimate

Forward guidance

The filing discusses Centessa Pharmaceuticals's outlook, capital deployment, and key risks without relying solely on numeric EPS guidance.

Tailwinds

  • Centessa Pharmaceuticals cited execution on strategic priorities in the filing.
  • Balance sheet and liquidity support continued operations.
  • Pipeline milestones remain the primary value driver.

Headwinds

  • GAAP profitability remained under pressure in the quarter.
  • Macro, competitive, and cost pressures may affect margins.
  • Segment mix and one-time items can affect comparability.
  • Clinical-stage spend continues ahead of commercial revenue.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q3 2025

Historical avgQ3 2025

+1.0%

Avg return

Earnings day

+0.0%

Avg return

5 days after

+4.0%

Avg return

30 days after

55%

11 / 20 earnings

Positive

+19.4%

Q2 2024

Best reaction

-14.6%

Q2 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-0.1%-0.3%+0.3%
Q4 2025-4.2%+6.1%+45.9%
Q3 2025-5.2%-5.9%+26.0%
Q1 2025-1.2%-1.6%-0.6%
Q4 2024-4.9%-12.3%-18.2%
Q3 2024+8.1%-4.4%+0.8%
Q2 2024+19.4%+18.5%+43.1%
Q1 2024+0.8%-1.1%+8.1%
Q4 2023-0.2%+2.1%-19.6%
Q3 2023+6.8%+13.4%+7.1%
Q2 2023+3.6%-4.2%+1.0%
Q1 2023+0.2%+0.9%-0.4%
Q4 2022-1.3%-3.1%+21.0%
Q3 2022+5.3%+4.7%+15.1%
Q2 2022-14.6%-22.4%-19.4%
Q1 2022+2.0%-15.7%-21.1%
Q4 2021-0.2%+9.6%-3.0%
Q3 2021+2.5%+9.3%-9.9%
Q1 2021+1.7%+3.4%+2.1%
Q2 2021+1.7%+3.4%+2.1%
Q4 2020

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