NASDAQ$CNTA

Centessa Pharmaceuticals plc · Q1 2026 earnings

Q1 2026 earnings · · Investor relations

Briefing

Centessa Pharmaceuticals reported Q1 2026 net loss of $79.2M and a Lilly acquisition agreement at $38 per share plus CVRs.

Centessa reported a Q1 2026 net loss of $79.2 million, or $(0.52) per share. Subsequent to quarter end, the company entered a transaction agreement for Lilly to acquire all shares for $38.00 cash plus contingent value rights up to $9.00 per share on milestones.

  • Net loss $(79.2)M; loss per share $(0.52).
  • Lilly acquisition announced March 31, 2026 at $38 + CVRs.
  • Pipeline of asset-centric biotech programs.
  • R&D spend drives quarterly loss.
  • Transaction closing subject to court and regulatory approvals.

Headline financials

Total Revenue

$0.00

Previous: $15M-100.0%
EPS (adj)

-$0.52

Previous: -$0.20-160.0%
Net Income

-$79.2M

Previous: -$26.1M-203.2%
Operating Income

-$79.8M

Previous: -$30.8M-159.2%

Revenue & EPS history

Centessa · Revenue · Quarterly

$0

Q1 2026-100%vs Q1 2025
Beat estimate in 0 of 1 quarters(0%)
ActualEstimate

Forward guidance

Forward outlook dominated by pending Lilly acquisition rather than standalone guidance.

Tailwinds

  • Strategic acquisition premium for shareholders.
  • Diversified pipeline assets.

Headwinds

  • Large quarterly loss pre-deal.
  • CVR milestones may not pay out.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q1 2026

Historical avgQ1 2026

+1.0%

Avg return

Earnings day

+0.0%

Avg return

5 days after

+4.0%

Avg return

30 days after

55%

11 / 20 earnings

Positive

+19.4%

Q2 2024

Best reaction

-14.6%

Q2 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-0.1%-0.3%+0.3%
Q4 2025-4.2%+6.1%+45.9%
Q3 2025-5.2%-5.9%+26.0%
Q1 2025-1.2%-1.6%-0.6%
Q4 2024-4.9%-12.3%-18.2%
Q3 2024+8.1%-4.4%+0.8%
Q2 2024+19.4%+18.5%+43.1%
Q1 2024+0.8%-1.1%+8.1%
Q4 2023-0.2%+2.1%-19.6%
Q3 2023+6.8%+13.4%+7.1%
Q2 2023+3.6%-4.2%+1.0%
Q1 2023+0.2%+0.9%-0.4%
Q4 2022-1.3%-3.1%+21.0%
Q3 2022+5.3%+4.7%+15.1%
Q2 2022-14.6%-22.4%-19.4%
Q1 2022+2.0%-15.7%-21.1%
Q4 2021-0.2%+9.6%-3.0%
Q3 2021+2.5%+9.3%-9.9%
Q1 2021+1.7%+3.4%+2.1%
Q2 2021+1.7%+3.4%+2.1%
Q4 2020

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