NASDAQ$CCCC

C4 Therapeutics Inc · Q2 2025 earnings

Q2 2025 earnings · · Before market open · Investor relations

Briefing

C4 Therapeutics reported its financial results for the second quarter ended June 30, 2025, with collaboration revenue and continued net losses.

C4 Therapeutics generated $6.5 million in revenue from its collaboration agreements during Q2 2025. The company reported a net loss of $26.0 million and an operating loss of $28.5 million while advancing its targeted protein degradation programs. Cash and cash equivalents stood at $78.2 million with additional marketable securities supporting operations.

  • Q2 2025 collaboration revenue totaled $6.5 million, led by contributions from the MKDG and Roche agreements.
  • Net loss for the quarter was $26.0 million, with R&D expenses at $26.2 million reflecting ongoing clinical development.
  • Cash position remained solid at $78.2 million alongside $136.4 million in current marketable securities.
  • Weighted average shares outstanding were approximately 71.0 million, resulting in a basic and diluted EPS of $(0.37).

Headline financials

Total Revenue

$6.46M

Previous: $12M-46.2%
EPS (adj)

-$0.37

Previous: -$0.26-42.3%
Research and Development Expense

$26.2M

Previous: $23.8M+10.3%
General and Administrative Expense

$8.77M

Previous: $9.7M-9.6%
Weighted Average Shares Outstanding

71.0M

Previous: 68.8M+3.2%
Interest and Other Income Net

$2.48M

Previous: $3.73M-33.4%
Capital Expenditures

-$185K

Previous: -$197K+6.1%
Net Income

-$26M

Previous: -$17.7M-46.9%
Operating Income

-$28.5M

Previous: -$21.4M-32.9%
Cash & Equivalents

$78.2M

No prior period
Total Assets

$297M

No prior period

Revenue & EPS history

C4 Therapeutics · Revenue · Quarterly

$6.46M

Q2 2025-46.2%vs Q2 2024
Beat estimate in 8 of 15 quarters(53%)
ActualEstimate

Revenue by segment

C4 Therapeutics · $6.46M total across 4 segments · Q2 2025

  • MKDG Agreement
    $3.43M
  • Roche Agreement
    $1.93M
  • Merck Agreement
    $1.05M
  • Betta Agreement
    $54K

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 17 quarterly earnings reports

Historical avg

+2.2%

Avg return

Earnings day

+4.1%

Avg return

5 days after

-1.1%

Avg return

30 days after

40%

10 / 25 earnings

Positive

+30.9%

Q2 2025

Best reaction

-10.0%

Q4 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q2 2024
Q2 2025+30.9%
Q1 2026+0.0%+13.0%+22.2%
Q4 2025+0.4%+17.4%+13.9%
Q3 2025-2.0%-10.0%+8.0%
Q1 2025-0.7%-1.4%+21.7%
Q4 2024-1.9%-10.2%-34.0%
Q3 2024+1.4%+10.1%-17.7%
Q1 2024+0.1%-9.1%-31.4%
Q4 2023+24.0%+34.5%+13.4%
Q3 2023-6.0%+21.5%+7.4%
Q2 2023-1.7%-3.1%-33.8%
Q1 2023+4.8%+5.6%+8.0%
Q4 2022-10.0%-11.0%-40.2%
Q3 2022-8.1%-6.4%-11.8%
Q2 2022+16.7%+6.9%-8.7%
Q1 2022-8.1%-19.3%-24.4%
Q4 2021+13.9%+13.9%+24.3%
Q3 2021-4.6%-7.3%-23.6%
Q2 2021+8.0%+5.6%+33.6%
Q1 2020-0.6%+7.4%+20.4%
Q1 2021-0.6%+7.4%+20.4%
Q2 2020+9.6%+7.2%-19.8%
Q3 2019-3.7%+8.3%+8.3%
Q3 2020-3.7%+8.3%+8.3%
Q4 2019-3.7%+8.3%+8.3%
Q1 2019
Q4 2018

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