NASDAQ$CCCC

C4 Therapeutics Inc · Q1 2022 earnings

Q1 2022 earnings · · Investor relations

Briefing

Reported financial results and business highlights for the first quarter of 2022.

C4 Therapeutics reported first quarter 2022 financial results, highlighting clinical data from the CFT7455 Phase 1/2 trial presented at AACR and the initiation of a Phase 1/2 clinical trial for CFT8634. The company's cash, cash equivalents, and marketable securities totaled $421.7 million as of March 31, 2022, expected to provide runway to the end of 2024.

  • Presented clinical data from Cohort A of the CFT7455 Phase 1/2 clinical trial at AACR, demonstrating deep and durable degradation of IKZF1/3.
  • Initiated a Phase 1/2 clinical trial for CFT8634 for patients with synovial sarcoma and SMARCB1-null solid tumors.
  • Showcased the potential of the TORPEDO® platform at AACR with pre-clinical presentations on CFT7455, CFT8634, and CFT1946.
  • Cash, cash equivalents, and marketable securities totaled $421.7 million as of March 31, 2022, expected to provide runway to the end of 2024.

Headline financials

Total Revenue

$7.65M

Previous: $7.43M+3.1%
EPS (adj)

-$0.65

Previous: -$0.49-32.7%
Research and development expense

$26.2M

No prior period
General and administrative expense

$12.8M

No prior period
Capital Expenditures

$172K

Previous: $421K-59.1%
Free Cash Flow

-$26.8M

Previous: -$25.4M-5.6%
Net Income

-$31.6M

Previous: -$21M-50.7%
Operating Income

-$31.4M

Previous: -$20.5M-53.0%
Gross Profit

$6.17M

No prior period
Cash & Equivalents

$422M

Previous: $94.9M+344.3%
Total Assets

$515M

Previous: $374M+37.8%
Stock-Based Comp

$8.94M

Previous: $3.85M+132.5%

Revenue & EPS history

C4 Therapeutics · Revenue · Quarterly

$7.65M

Q1 2022+3.1%vs Q1 2021
Beat estimate in 3 of 10 quarters(30%)
ActualEstimate

Revenue by segment

C4 Therapeutics · $11.1M total across 1 segment · Q3 2023

  • Collaboration agreements
    $11.1M+63.9%

Forward guidance

C4T anticipates several milestones including continued enrollment in the CFT7455 and CFT8634 Phase 1/2 trials, submission of an IND application and initiation of a Phase 1 trial for CFT1946, and completion of IND-enabling activities for CFT8919.

Tailwinds

  • Continued enrollment of the Phase 1/2 trial throughout 2022 for CFT7455 to inform the identification of a recommended Phase 2 dose(s) and schedule(s) for MM and NHL.
  • Dose the first patient in CFT8634 Phase 1/2 clinical trial in 1H 2022 and continue to enroll the trial throughout 2022, informing the identification of a recommended Phase 2 dose for synovial sarcoma and SMARCB1-null solid tumors.
  • Submit an IND application and initiate a Phase 1 trial of CFT1946 in BRAF V600X-driven cancers including melanoma, colorectal and non-small cell lung cancer in 2H 2022.
  • Complete IND-enabling activities for CFT8919 by year-end 2022.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 19 quarterly earnings reports · overlaid with Q1 2022

Historical avgQ1 2022

+1.0%

Avg return

Earnings day

+4.1%

Avg return

5 days after

-2.2%

Avg return

30 days after

38%

9 / 24 earnings

Positive

+24.0%

Q4 2023

Best reaction

-10.0%

Q4 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+0.0%+13.0%
Q4 2025+0.4%+17.4%+13.9%
Q3 2025-2.0%-10.0%+8.0%
Q1 2025-0.7%-1.4%+21.7%
Q4 2024-1.9%-10.2%-34.0%
Q3 2024+1.4%+10.1%-17.7%
Q1 2024+0.1%-9.1%-31.4%
Q4 2023+24.0%+34.5%+13.4%
Q3 2023-6.0%+21.5%+7.4%
Q2 2023-1.7%-3.1%-33.8%
Q1 2023+4.8%+5.6%+8.0%
Q4 2022-10.0%-11.0%-40.2%
Q3 2022-8.1%-6.4%-11.8%
Q2 2022+16.7%+6.9%-8.7%
Q1 2022-8.1%-19.3%-24.4%
Q4 2021+13.9%+13.9%+24.3%
Q3 2021-4.6%-7.3%-23.6%
Q2 2021+8.0%+5.6%+33.6%
Q1 2020-0.6%+7.4%+20.4%
Q1 2021-0.6%+7.4%+20.4%
Q2 2020+9.6%+7.2%-19.8%
Q3 2019-3.7%+8.3%+8.3%
Q4 2019-3.7%+8.3%+8.3%
Q3 2020-3.7%+8.3%+8.3%
Q1 2019
Q4 2018

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