NASDAQ$BEAM

Beam Therapeutics Inc. · Q4 2021 earnings

Q4 2021 earnings · · Investor relations

Briefing

Pipeline and business highlights were reported, 2022 milestones were planned, and fourth quarter and full year 2021 financial results were announced.

Beam Therapeutics reported a strong cash position of $1.2 billion, including a $300 million upfront payment from Pfizer, to support milestones across ex vivo and in vivo base editing programs. The company is advancing its sickle cell disease strategy with planned clinical trials for BEAM-101 and BEAM-102.

  • Executed a multi-target research collaboration with Pfizer, receiving a $300 million upfront payment.
  • Advanced ex vivo base editing programs for sickle cell disease.
  • Presented preclinical data on multiplex edited CAR T-cells for CD5-positive tumors.
  • Plans to enroll the first subject in the Phase 1/2 clinical trial of BEAM-101 for the treatment of SCD in the second half of 2022.

Headline financials

Total Revenue

$51.1M

Previous: $6K+851050.0%
EPS (adj)

-$0.95

Previous: -$1.69+43.8%
R&D expenses

$96.8M

No prior period
G&A expenses

$17.8M

No prior period
Capital Expenditures

$13.4M

Previous: $8.13M+64.5%
Free Cash Flow

-$11.5M

Previous: -$32.4M+64.4%
Net Income

-$64.7M

Previous: -$95.5M+32.2%
Operating Income

-$63.5M

Previous: -$40.8M-55.6%
Gross Profit

$46.1M

Previous: -$38M+221.1%
Cash & Equivalents

$966M

Previous: $162M+495.4%
Total Assets

$1.47B

Previous: $452M+226.4%
Stock-Based Comp

$15.5M

Previous: $6.81M+127.7%

Revenue & EPS history

Beam Therapeutics · Revenue · Quarterly

$51.1M

Q4 2021+851,050%vs Q4 2020
Beat estimate in 9 of 12 quarters(75%)
ActualEstimate

Revenue by segment

Beam Therapeutics · $6K total across 1 segment · Q2 2021

  • License & collaboration revenue
    $6K

Forward guidance

Beam Therapeutics anticipates several milestones in 2022, including IND submissions and clinical trial initiations for its ex vivo HSC and T cell programs, as well as advancing its in vivo LNP liver-targeting programs.

Tailwinds

  • Enroll the first subject in the Phase 1/2 clinical trial of BEAM-101 for the treatment of SCD in the second half of 2022
  • Submit an investigational new drug (IND) application for BEAM-102 for the treatment of SCD in the second half of 2022
  • Submit an IND application for BEAM-201 for the treatment of relapsed/refractory T cell acute lymphoblastic leukemia/T cell lymphoblastic lymphoma (T-ALL/TLL) in the second half of 2022
  • Nominate a second CAR-T development candidate in 2022
  • Initiate IND-enabling studies for BEAM-301

Headwinds

  • Ability to develop, obtain regulatory approval for, and commercialize our product candidates, which may take longer or cost more than planned
  • Ability to raise additional funding, which may not be available
  • Ability to obtain, maintain and enforce patent and other intellectual property protection for our product candidates
  • Preclinical testing of our product candidates and preliminary or interim data from preclinical studies and clinical trials may not be predictive of the results or success of ongoing or later clinical trials
  • Product candidates may experience manufacturing or supply interruptions or failures

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q4 2021

Historical avgQ4 2021

+1.1%

Avg return

Earnings day

-0.1%

Avg return

5 days after

+3.6%

Avg return

30 days after

56%

14 / 25 earnings

Positive

+21.8%

Q4 2023

Best reaction

-11.1%

Q3 2023

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-2.8%-2.4%-9.3%
Q4 2025+14.1%+0.5%-16.6%
Q3 2025-6.4%-8.4%+19.2%
Q1 2025+3.9%-0.2%-1.1%
Q4 2024-3.1%-14.5%-27.9%
Q3 2024+9.3%+11.1%+3.9%
Q2 2024-4.5%-4.5%-5.6%
Q1 2024-2.4%-6.7%+5.7%
Q4 2023+21.8%+11.3%-7.7%
Q3 2023-11.1%-12.2%+5.6%
Q2 2023+2.2%+0.0%-1.5%
Q1 2023+1.9%+4.3%-6.7%
Q4 2022-1.3%+0.3%-22.7%
Q3 2022-10.3%+19.0%+3.0%
Q2 2022+3.2%+8.5%-10.4%
Q1 2022+0.3%-0.6%+12.6%
Q4 2021-1.7%-14.3%-20.5%
Q3 2021+9.1%+2.9%-11.4%
Q2 2021+1.0%-5.6%+1.0%
Q1 2021+4.3%+12.2%+37.1%
Q4 2020-4.4%-5.6%-22.3%
Q3 2020+2.5%-1.4%+109.9%
Q2 2020-5.1%-3.5%+8.6%
Q1 2020+3.3%+3.4%+23.1%
Q4 2019+3.3%+3.4%+23.1%
Q3 2019
Q2 2019
Q1 2019
Q4 2018
Q3 2018
Q2 2018
Q1 2018

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