NASDAQ$BCYC

Bicycle Therapeutics plc · Q2 2022 earnings

Q2 2022 earnings · · Investor relations

Briefing

Reported second quarter 2022 financial results and provided corporate update.

Bicycle Therapeutics reported its second quarter financial results, highlighting clinical progress across its pipeline and the expansion of its collaboration with Genentech. The company's cash and cash equivalents totaled $372.8 million as of June 30, 2022, providing a financial runway into 2025.

  • Continued clinical progress across pipeline, including dosing of the first patient in expansion cohorts of Phase I/II study of BT5528.
  • Expansion of Genentech exclusive strategic collaboration, triggering a $10 million payment to Bicycle in Q3.
  • Cash and cash equivalents of $372.8 million as of June 30, 2022, excludes $9.8 million UK R&D tax credit received in July and Genentech payment.
  • Financial runway expected into 2025.

Headline financials

Total Revenue

$4.38M

Previous: $1.79M+145.3%
EPS (adj)

-$0.90

Previous: -$0.74-21.6%
Capital Expenditures

-$14.6M

Previous: -$794K-1733.1%
Free Cash Flow

-$41.4M

Previous: -$18.7M-121.2%
Net Income

-$26.8M

Previous: -$17.9M-49.8%
Operating Income

-$27.3M

Previous: -$17.3M-58.0%
Gross Profit

-$13.9M

Previous: -$9.55M-45.7%
Cash & Equivalents

$373M

Previous: $199M+87.6%
Total Assets

$445M

Previous: $226M+97.1%
Stock-Based Comp

$5.67M

Previous: $2.58M+120.3%

Revenue & EPS history

Bicycle · Revenue · Quarterly

$4.38M

Q2 2022+145.3%vs Q2 2021
Beat estimate in 6 of 14 quarters(43%)
ActualEstimate

Forward guidance

Bicycle Therapeutics anticipates continued advancement of its product candidates, including BT5528, BT8009 and BT7480, progression of its clinical trials, and expansion of its discovery efforts and early development pipeline.

Tailwinds

  • Advancement of product candidates.
  • Progression of clinical trials.
  • Expansion of discovery efforts.
  • Early development pipeline growth.
  • Strong balance sheet.

Headwinds

  • Risks to clinical trial site initiation.
  • Patient enrollment and follow-up challenges.
  • Uncertainties in clinical trials and development.
  • Potential adverse effects from product candidates.
  • Risk of inaccurate financial runway projections.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q2 2022

Historical avgQ2 2022

+1.2%

Avg return

Earnings day

-1.6%

Avg return

5 days after

+0.1%

Avg return

30 days after

52%

14 / 27 earnings

Positive

+19.3%

Q4 2019

Best reaction

-10.8%

Q1 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-0.2%+3.6%-0.8%
Q4 2025-4.2%-13.9%+1.8%
Q3 2025+6.7%-16.0%-8.6%
Q1 2025+6.1%-13.6%-4.0%
Q4 2024-1.3%-2.5%-18.3%
Q3 2024-5.5%-2.2%-15.1%
Q2 2024-0.7%+2.1%-10.0%
Q1 2024+1.6%-4.6%-8.3%
Q4 2023+3.1%+9.5%+14.9%
Q3 2023+1.2%-0.7%-2.3%
Q2 2023+1.3%-2.8%-4.1%
Q1 2023-0.4%+2.5%+15.7%
Q4 2022-1.9%-5.5%-6.2%
Q3 2022-3.2%+0.8%+29.6%
Q2 2022+14.8%+17.7%+12.8%
Q1 2022-10.8%-22.6%-33.6%
Q4 2021-1.2%-9.7%-7.6%
Q3 2021+0.7%+2.5%-6.8%
Q2 2021+1.8%+2.3%+36.0%
Q1 2021+1.9%-1.3%-5.5%
Q4 2020+1.9%+2.0%+3.8%
Q3 2020-1.5%+3.1%+5.2%
Q2 2020-0.2%+0.0%+5.8%
Q1 2020+0.7%+6.6%+23.2%
Q4 2019+19.3%+1.5%-2.3%
Q3 2019-4.2%-7.7%-4.8%
Q2 2019+5.9%+5.4%-6.6%
Q1 2019
Q4 2018
Q3 2018
Q2 2018
Q1 2018
Q4 2017

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