NASDAQ$ARWR
Arrowhead Pharmaceuticals Inc · Q3 2024 earnings
Q3 2024 earnings · · Investor relations
Briefing
Arrowhead Pharmaceuticals reported third quarter results, highlighted by clinical progress and strategic financial moves.
Arrowhead Pharmaceuticals reported its fiscal year 2024 third quarter results, featuring significant clinical progress with presentations and publications. The company also strengthened its balance sheet through a strategic financing agreement and a milestone payment, focusing on advancing plozasiran towards potential commercialization in 2025.
- Plozasiran achieved statistically significant median reductions in triglycerides up to 80% and mean reductions in APOC3 up to 94% at month 10 in the PALISADE study.
- Arrowhead initiated pivotal Phase 3 SHASTA-3 and SHASTA-4 studies of plozaisran in patients with severe hypertriglyceridemia.
- The company closed a strategic financing agreement with Sixth Street for a $500 million senior secured credit facility.
- Arrowhead received a $50 million milestone payment from Royalty Pharma following the completion of enrollment of the Phase 3 OCEAN(a) - Outcomes Trial of olpasiran.
Headline financials
Revenue & EPS history
Arrowhead Pharmaceuticals · Revenue · Quarterly
$0
Forward guidance
Arrowhead Pharmaceuticals is focusing on advancing plozasiran towards potential commercialization in 2025, provided it receives regulatory approval. The company is also expanding innovation across its pipeline of RNAi therapeutics and plans to initiate a Phase 3 cardiovascular outcomes trial called CAPITAN for plozasiran.
Tailwinds
- Potential commercial launch of plozasiran in 2025.
- Advancing plozasiran into a Phase 3 cardiovascular outcomes trial called CAPITAN.
- Plozasiran demonstrated a favorable safety profile in the PALISADE study.
- ARO-RAGE has shown a favorable safety profile to date.
- The company is expanding innovation across its pipeline of RNAi therapeutics.
Headwinds
- Commercialization of plozasiran is contingent upon regulatory approval.
- The company reported an operating loss of $176.141 million for the quarter.
- The company reported a net loss attributable to Arrowhead Pharmaceuticals, Inc. of $170.793 million.
- The company's cash, cash equivalents and restricted cash decreased from $110.891 million to $69.399 million.
- There have been treatment emergent adverse events reported in studies.
Historical earnings impact
How earnings announcements have historically affected this stock's price.
Avg. return before/after earnings
Based on 20 quarterly earnings reports · overlaid with Q3 2024
+0.0%
Avg return
Earnings day
+4.2%
Avg return
5 days after
+10.8%
Avg return
30 days after
38%
24 / 64 earnings
Positive
+39.2%
Q4 2024
Best reaction
-26.7%
Q4 2023
Worst reaction
| Quarter | Report date | Reaction (Day 0) | +5 days | +30 days |
|---|---|---|---|---|
| Q2 2026 | +1.6% | +0.1% | -6.1% | |
| Q1 2026 | -0.2% | -4.8% | -7.5% | |
| Q4 2025 | +23.2% | +20.2% | +49.9% | |
| Q2 2025 | +9.4% | +12.5% | +16.1% | |
| Q1 2025 | -5.2% | +0.2% | -24.3% | |
| Q4 2024 | +39.2% | +38.5% | +3.9% | |
| Q3 2024 | -6.4% | -8.6% | -11.1% | |
| Q2 2024 | -12.5% | -9.2% | -5.2% | |
| Q1 2024 | -1.2% | +1.7% | +3.7% | |
| Q4 2023 | -26.7% | -13.8% | +5.8% | |
| Q3 2023 | -13.1% | -8.8% | -7.7% | |
| Q2 2023 | +12.5% | +15.8% | -2.9% | |
| Q1 2023 | -8.5% | -9.9% | -19.3% | |
| Q4 2022 | +1.7% | +15.0% | +27.3% | |
| Q3 2022 | +3.6% | +2.5% | -11.1% | |
| Q2 2022 | -11.5% | -3.3% | -0.7% | |
| Q1 2022 | -11.1% | -5.4% | -22.1% | |
| Q4 2021 | -0.3% | +1.3% | -1.8% | |
| Q3 2021 | -2.0% | -7.4% | +2.2% | |
| Q2 2021 | -5.4% | -5.5% | +3.2% | |
| Q1 2021 | +12.6% | +11.8% | -14.1% | |
| Q4 2020 | -12.2% | -8.4% | +24.1% | |
| Q3 2020 | -7.0% | -8.5% | -18.3% | |
| Q2 2020 | -0.3% | +5.0% | -0.5% | |
| Q1 2020 | -6.4% | -2.4% | -23.9% | |
| Q4 2019 | +37.6% | +48.4% | +31.2% | |
| Q3 2019 | -2.1% | -0.2% | +17.6% | |
| Q2 2019 | +8.0% | +0.1% | +50.2% | |
| Q1 2019 | +13.2% | +25.4% | +33.0% | |
| Q4 2018 | +11.2% | +4.8% | +9.8% | |
| Q3 2018 | +13.2% | +18.6% | +36.2% | |
| Q2 2018 | +15.8% | +27.2% | +33.5% | |
| Q1 2018 | -6.2% | -3.4% | +30.9% | |
| Q4 2017 | -3.1% | -10.5% | +43.6% | |
| Q3 2017 | +8.9% | +13.6% | +69.2% | |
| Q2 2017 | +13.5% | +6.4% | +3.8% | |
| Q1 2017 | +3.2% | +3.7% | +12.1% | |
| Q4 2016 | +0.0% | -1.6% | +62.2% | |
| Q3 2016 | -1.2% | +1.0% | +29.7% | |
| Q2 2016 | -3.1% | — | — | |
| Q1 2016 | -0.9% | — | — | |
| Q4 2015 | -1.1% | — | — | |
| Q3 2015 | +12.1% | — | — | |
| Q2 2015 | -10.9% | — | — | |
| Q1 2015 | -1.1% | — | — | |
| Q4 2014 | -6.2% | — | — | |
| Q3 2014 | +1.2% | — | — | |
| Q2 2014 | -10.7% | — | — | |
| Q1 2014 | -2.6% | — | — | |
| Q4 2013 | +7.3% | — | — | |
| Q3 2013 | +2.5% | — | — | |
| Q2 2013 | +10.2% | — | — | |
| Q1 2013 | -1.8% | — | — | |
| Q4 2012 | -7.2% | — | — | |
| Q3 2012 | -16.8% | — | — | |
| Q2 2012 | -4.5% | — | — | |
| Q1 2012 | -1.4% | — | — | |
| Q4 2011 | +0.5% | — | — | |
| Q2 2011 | +0.5% | — | — | |
| Q3 2011 | -12.4% | — | — | |
| Q3 2010 | -12.4% | — | — | |
| Q4 2010 | -12.4% | — | — | |
| Q1 2011 | -5.6% | — | — | |
| Q2 2010 | -8.1% | — | — |
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